Báo cáo y học: "An Increased Risk of Osteoporosis during Acquired

Báo cáo y học: "An Increased Risk of Osteoporosis during Acquired Immunodeficiency Syndrome"

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Báo cáo y học: "No increased risk of infant hypospadias after maternal use of loratadine in early pregnancy"

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Báo cáo y học: "An unusual case of gout in the wrist: the importance of monitoring medication dosage and interaction. A case report"

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Báo cáo y học: "Two-year Outcome of Turkish Patients Treated with Zotarolimus Versus Paclitaxel Eluting Stents in an Unselected Population with Coronary Artery Disease in the Real World: A Prospective Non-randomized Registry in Southern Turk

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Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf

... replacement of Gly262 byAla resulted in an inactive enzyme. Substitution of Gly261by Ala resulted to an enzyme with lower stability and increased energy of activation. The double mutant G261A/ Y2 69A ... Bouriotis1,21Department of Biology, Division of Applied Biology and Biotechnology, University of Crete, Greece;2Institute of Molecular Biologyand Biotechnology (IMBB), Enzyme Technology Division, and ... study [16], we explored the possibility of modifying the psychrophilic properties of an enzyme byintroducing, via mutagenesis, predictable ﬂexibility changesto key active site residues of the...

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Báo cáo Y học: An active site homology model of phenylalanine ammonia-lyase from Petroselinum crispum docx

... Organic Chemistry, University of Karlsruhe, Germany;2Institute for Organic Chemistry, Budapest University of Technology and Economics, HungaryThe plant enzyme phenylalanine ammonia-lyase (PAL,EC ... counterpart of residue Y2 80 at the active site of HAL is Y3 51 in the amino-acid sequence of PAL. PAL mutant Y3 51F showed a byfactor 235 reduced activity compared to that of the wild-type enzyme. ... catalytically essential moiety rather than the dehydro-alanine (Fig. 1) [7]. It has been proposed that this MIOgroup is generated by autocatalytic cyclization of the A142-S143-G144 moiety of...

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Báo cáo Y học: Expression and characterization of recombinant vitamin K-dependent c-glutamyl carboxylase from an invertebrate, Conus textile doc

... onConuscarboxylase activityOur work [43] and that of Bandyopadhyay et al.[42]demonstrated the importance of the propeptide in directingc-carboxylation of Conus precursor substrates by the Conuscarboxylase. ... carboxylase activity. Further, usinginsect cells, this expression system provides a source of Conus carboxylase free of endogenous carboxylase andcarboxylase substrates.Molecular mass analysis of ... cDNAobtained by library screening.Fig. 4. Eﬀect of propeptides on carboxylase activity. The eﬀect of proFIX18, proPT18 and pro-e-TxIX/12 on FLEEL carboxylation bythe recombinant bovine carboxylase...

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Báo cáo Y học: The solution structure of gomesin, an antimicrobial cysteine-rich peptide from the spider pptx

... of PG-1 isparticularly hydrophobic as it contains only a polar residuesLeu5, Cys6, Tyr7, Cys8, Phe12, Cys13, Val14, Cys15 andVal16 alternatively distributed on each side of the b sheet[9,10]. ... structure clearlydisplays (a) an hydrophobic face formed by a largeaggregate of hydrophobic residues (Leu5, Tyr7, Val12,and T yr14) w hich are located on the concave surface of t hepeptide; ... Strong daN(i,i +1)NOEsinseg-ments (Cys2–Cys6 and Cys11–Cys15) a re indicative of twoextended strands of b sheet. This hypothesis is c onﬁrmed bythe presence of long-distance Ha(i)-Ha(j) co nnectivitiesdetected...

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Báo cáo y học: "Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections"

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Báo cáo y học: "The evolving story of medical emergency teams in quality improvement"

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