Báo cáo y học: "Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary"
Báo cáo y học: "Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary"
... Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary Corresponding address: Andrew E. Czeizel Foundation for the Community Control of Hereditary Diseases, 1148 Budapest, ... characteristics of the study population, etc. In Hungary the total prevalence of congenital abnormalities was 66.83 per 1000 informative offspring in the 1980s and within this, the total rate of major ... corrected by drugs immediately after birth. In Hungary 25.2% of congenital abnormalities were prevented by these methods. Previously the selective abortion, i.e. termination of pregnancy after the prenatal...
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Báo cáo y học: " Rationale for one stage exchange of infected hip replacement using uncemented implants and antibiotic impregnated bone graft"
... biofilms, culturing the sonication fluid is likely to raise sensitivity of cultures significantly. Especially in patients having received antimicrobial therapy within 14 days before culture the ... criteria, among them Vancomycin seems to be the most widely evaluated one. Vancomycin is one of the antibiotics with intracellular bactericidal activity and therefore should cover SCVs of staphylococci ... are often missed by conventional culture. The problem of diagnosis markedly increases taking into account the issue of bacterial phenotypes inside biofilms. Sonication of explanted devices may...
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Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"
... several examples of theory being misled by mistaken data. Indeed, early reports of SMGT were compared with the (then contemporary) claims of “cold fusion” in physics [36]. By contrast, the second possible ... microscope, the needle is guided through the cytoplasm towards one of the zygote’s pronuclei. A nanolitre quantity of DNA solution is injected, bringing typically two hundred DNA molecules into the pronucleus. ... probably be usable with human zygotes, the major inherent problems of the method render it less than ideal for human germline gene therapy. A major problem is the relatively low rate of transgene...
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Tài liệu Báo cáo khoa học: "Methods for the Qualitative Evaluation of Lexical Association Measures" doc
... identification: (i) the syntactic homogeneity of the base data, i.e.,whether the set of candidate data consists only of adjective-noun, noun-verb, etc. pairs or whetherdifferent types of word combinations ... to the recall curves (Figures 3 and4), we find: (i) Examination of 50% of the datain the SLs leads to identification of between 75%(AdjN) and 80% (PNV) of the TPs. (ii) For the first 40% of the ... performance of AMs withindifferent frequency strata. For instance, there isa widely held belief thatand are inferiorto other measures because they overestimate the collocativity of low-frequency candidates...
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Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... these enzymescatalyse an hydrolytic reaction with production of urea. The question arises therefore as to whether a similar or identicalmechanism is involved in catalysis by these enzymes, whichapparently ... weconclude that the lower activity of the mutant may beascribed to the loss of an acceptor hydrogen bond to ametal-bound hydroxide, as a consequence of replacement of a carboxylate oxygen with an ... asignificantly altered affinity for the activating metal ion, arenot the explanations for the greatly decreased catalyticactivity of the D153N variant.To evaluate possible structural changes that may...
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Tài liệu Báo cáo Y học: Studies on the nonmevalonate pathway of terpene biosynthesis The role of 2C-methyl-D -erythritol 2,4-cyclodiphosphate in plants docx
... 2C-methyl-D-erythritol4-phosphate can be converted into a cyclic diphosphate by the consecutive action of 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, 4-diphosphocytidyl-2C-methyl-D-erythritolkinase ... the enzyme in D2O [54]; a rapidexchange was detected for the C-4 hydrogens and one of C-2hydrogens of IPP as well as for the (E)-methyl group of DMAPP, followed by a slower exchange (2% of ... exchange (2% of the isomerization rate) of the methyl group of IPP and the (Z)-methyl group of DMAPP, and an even slower exchange(0.5% of the isomerization rate) of the olefinic hydrogen of DMAPP corresponding...
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Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot
... particle density of the polydisperse sol-utes. For the functional dependence between the densityand molar mass of the fractionated emulsion particles,we assumed a spherical monolayer of Myr2Gro-PChosurrounding ... high-affinity ligand for anumber of cell surface receptors, thereby mediating the uptake of cholesterol and other complex lipids into the cell[12,13]. The three common isoforms of apoE, designatedapoE2 ... interacts with the emulsion surface [28]. It isnot known whether the apoE3 isoform displays a similarphenomenon on the surface of lipid particles.In the present study we develop methods for the characterization...
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Báo cáo khoa học: Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen pptx
... oxygen sensor inhuman cells; however, the underlying kinetic basis of the oxygen-sensingfunction of prolyl hydroxylase domain 2 is unclear. We report analyses of the reaction of prolyl hydroxylase ... Department of Chemistry and Oxford Centre for Integrative Systems Biology, Oxford, UK2 Department of Chemistry and Department of Biochemistry and Molecular Biology, The Pennsylvania State University, ... University Park,PA, USA3 Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, EgyptKeywords2-oxoglutarate; hypoxia-inducible factor;oxygen; oxygenase; prolyl hydroxylase;spectroscopyCorrespondenceC....
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Báo cáo khoa học: Principles behind the multifarious control of signal transduction ERK phosphorylation and kinase/phosphatase control potx
... drug, or the occurrence of mutations affecting the control by one enzyme, will therefore almost alwaysinterfere with the regulation of the signal transductionpathway by all regulatory mechanisms, ... envi-ronment of the system is constant i.e. any externalchange such as the addition of EGF should haveoccurred at or slightly before t ¼ 0. The equationthen defines the dynamics of the system in ... understoodcompletely, to what extent amplitude and duration of signaling are controlled by the kinases or phosphatasesin the system, and whether they are controlled differ-entially by some or all of them....
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Báo cáo y học: "Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections"
... values .The development of sepsis from a localized infection isa dynamic continuum and in the majority a sequelae ofCAP [54]. The severity of a disease determines the con-sumption of costly and ... levels may mirrorboth, the inflammatory cytokine response correlatedwith the severity of infection, as well as the presence ofdisease-relevant comorbidities, namely heart failure andrenal dysfunction ... ampli-fied cryptate emission (TRACE) technology assay (PCTKryptor®, B.R.A.H.M.S. AG, Hennigsdorf, Germany). Theassay has a detection limit of 0.02 μg/L and functionalassay sensitivity of 0.06 μg/L.Statistical...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnbáo cáo khoa học y họcbáo cáo y tế học đườngbáo cáo tuần sinh hoạt tập thể đầu năm họcmẫu báo cáo y tế học đườngNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Thơ nôm tứ tuyệt trào phúng hồ xuân hươngSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ