... promotes the folding and assembly of protein byrecognizing unfolded polypeptides and inhibiting intra- and intermolecular aggregation [17]. To investigate therole of BiP in the TSHR folding process, ... Nagayama, Y. , Namba, M., Yokoyama, N., Yamashita, S. &Niwa, M. (1998) Role of asparagine-linked oligosaccharides in protein folding, membrane targeting, and thyrotropin and auto-antibody binding ... maturation of the glycopro-teins synthesized in the endoplasmic reticulum involvesinteractions with molecular chaperones, which promotethe folding and assembly of the glycoproteins. In thisstudy,...