... MINIREVIEWNa+/K+-ATPase as a signal transducerZijian Xie and Amir AskariDepartment of Pharmacology, Medical College of Ohio, Toledo, USANa+/K+-ATPase as an energy transducing ion pump hasbeen ... myocytes as a model, our studies of the past fewyears [22–26] have clearly indicated that the same nontoxicconcentrations of ouabain that cause partial inhibition of Na+/K+-ATPase and an ... newer aspect of the biology of Na+/K+-ATPase; i.e. the mechanisms and the pathwaysby which the enzyme acts as a signal transducer to relaymessages, through protein–protein interactions, from...