... reactions, phlebitis induced by intravenous infusion of antineoplastic agents re-duces the completion of chemotherapy. The causative factors of phlebitis include the pH and osmotic pres-sure of ... and phlebitis caused by intravenous infusion of hypertonic solutions in animals [16]. As mentioned above, there has only been one report that DEX can reduce phl...
... per-formed by adopting the gating strategy defined by the International Society of Haematotherapy and Graft Engineering (ISHAGE) guidelines [27]. The method of the selection of stem/progenitor ... dietary restriction in combination with the following: 1. Daily sublingual treatments by vitamin B12 (1,000 g per day). 2. Oral supplements consisting of the following nutrients: 25...
... caffeine user group in response to the product containing caffeine and p-synephrine. The results of this study in- dicate that ingestion of a product containing bitter orange extract, caffeine ... contro-versy has existed regarding the safety of bitter orange extract and p-synephrine [8-11]. The safety of p-synephrine is clouded by its structural similarity to nor-epinephrine in...
... presented in Figure 1. A course consisted of continuous infusion of 5-FU at 400 or 500-550 mg/m2/day for days 1-5 and 8-12, infusion of CDDP at 40 mg/m2/day on days 1 and 8, and radia-tion at 2 Gy/day ... disap-pearance of circadian rhythm in the 5-FU plasma concentration of the higher dose can be explained by the inhibition of DPD. In conclusion, the dose-escalation...
... erythrocytes of 3 replicates was counted. Efficacy of invasion was calculated as the percentage of ring infected erythrocytes of treated cultures over the percentage of ring infected erythrocytes ... was maintained in culture as described by Trager and Jensen [8]. Cultures were synchronised by two rounds of sedimentation using gelatine. Briefly, cultures of approximately 5...
... purity of the protein was analyzed by SDS ⁄ PAGE
on a 15% polyacrylamide gel [42], followed by staining
with Coomassie Brilliant Blue. The protein concentration
was determined from UV absorption ... represents
6-carboxyfluorescein. All oligonucleotides were synthesized
by Hokkaido System Science. Hydrolysis of the substrate at
30 °C for 15 min and separation of the products on...
... states, indica-
ting changes in the internal dynamics and domain orienta-
tion of myosin. In the AdoPP[CH
2
]P state, approximately
half of the myosin heads reflected the motional state of
ADP–myosin, ... binding to actin.
Accordingly, our experiments support the view that the
rotational motion of myosin reflects functionally relevant
conformational changes during ATP hydrolysis by...
... determine how thyroid hormones interact with
xCTBP/xALDH1, resulting in the decrease in the formation
of retinoic acid from retinal, kinetics of the inhibition of
xCTBP/xALDH1 by T
3
was examined by ... later confirmed by examining both
the 3,3¢,5-triiodo-
L
-thyronine (T
3
) binding and the ALDH
activities of the recombinant xALDH1 [10]. The concen-
trations of the 59-kDa...
... hexa-coordinated,
possibly being bonded to His105 and Tyr148 as suggested
by docking simulations [7]. Upon drug binding, neither a
change in the haem-iron atom coordination number, nor in
the spin state ... Fasano
3
1
Department of Chemistry ‘IFM’, University of Torino, Italy;
2
Department of Biology, University ‘Roma Tre’, Rome, Italy;
3
Department of
Structural and Functional...
... effect of 1,25 vit-D or vehicle on chronic sep-sis induced by single IP injection of LPS is shown in
Int. J. Med. Sci. 2007, 4 192table 2. The LPS injection induced a septic condition in the ... and cer-tain interleukins play a key-role in initiating systemic inflammatory response syndrome (SIRS) and it is known that vitamin D may modulate the cytokine ex-pression from the...