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Tài liệu Báo cáo khoa học: A second novel dye-linked L-proline dehydrogenase complex is present in the hyperthermophilic archaeon Pyrococcus horikoshii OT-3 pptx

Tài liệu Báo cáo khoa học: A second novel dye-linked L-proline dehydrogenase complex is present in the hyperthermophilic archaeon Pyrococcus horikoshii OT-3 pptx

... No flavin compounds were bound to the a1subunit of PDH1, though it did contain one ADP-binding motif. This suggests the ADP-binding motif in the a1 subunit mediates the observed ATP binding,and ... analysis.This means that ATG, which was situated 7 bp down-stream from the 5¢-terminus of the predicted ORF, is the proper initial codon for the a1 gene. The N-terminalamino-acid sequence of the ... that the ADP-binding motif in the b1 subunit mediates FAD binding. On the otherhand, FMN was not detected bound to either subunit(Fig. 5B,C). We also extracted the flavin compoundsfrom the native...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "THERE STILL IS GOLD IN THE DATABASE MINE" potx

... resulted in this panel, which is supposed to debate the necessity of continuing work in this area rather than to debate technical issues in the area. And yet if this problem has been solved, where ... for all the Michigan doctors and Pennsylvania dentists, produced a list of all the people who were either doctors or dentists and who lived in either Michigan or Pennsylvania. This is the state ... display, update, and interaction in which the system acts like a helpful, intelligent, knowledgeable assistant. In this situation, the user carries on a dialogue (perhaps using speech) using...
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Processing Fluency and Aesthetic Pleasure: Is Beauty in the Perceiver''''s Processing Experience? pptx

Processing Fluency and Aesthetic Pleasure: Is Beauty in the Perceiver''''s Processing Experience? pptx

... instead from the processing experi-ences of the perceiver. Is beauty therefore in the eye of the beholder? In a sense it is, if folk wisdom thinks of the eye as the perceptual processes of the beholder.However, ... in higher percep-tual fiuency, and training in arts gives meaning to com-plex structures in paintings, poems, or music, whichresults in an additional increase in processing ease. Ac-cordingly, ... perceiversinterpret the positive affect elicited by processing flu-ency as their response to the target, resulting in morepositive evaluations. This assumption is consistentwith the feelings-as-information...
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Báo cáo khoa học: Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca2+ Lorenz Schild1 and Georg Reiser2 doc

Báo cáo khoa học: Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca2+ Lorenz Schild1 and Georg Reiser2 doc

... sug-gests that the mitochondrial injury is caused by open-ing of the mPTP. There is evidence that ADP inhibitsopening of the mPTP by occupying binding siteslocated in the inner and outer ... relevance in brain, because in this tissue glucose is metabolized providing the NADH-yielding substrate pyruvate. Under these con-ditions, some succinate is formed by the citric acidcycle, oxidizing ... be involved in the patho-genesis of neurodegenerative processes such as tissueinfarction resulting from transient ischemia in stroke[1,2]. Investigations of in vivo ischemia showed thatbrains...
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Báo cáo khoa học: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid b-protein doc

Báo cáo khoa học: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid b-protein doc

... polyglu-tamine-expanded huntingtin [18], the tumor suppressorgene p53 [19] and Parkin-associated endothelin recep-tor-like receptor [20]. In this study, we addressed whether Synoviolin is involved in the degradation ... SupportingInformation). We also determined the levels of c-secre-tase-unrelated ER protein (calnexin) and cytoskeletonprotein (tubulin) in these cells as the internal controlproteins. The calnexin ... Interestingly, amyloid b-protein generation was increased by the overexpression of Synoviolin, although the nicastrin level was decreased.Thus, Synoviolin-mediated ubiquitination is involved in the...
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Báo cáo khoa học: Protein kinase Ch activity is involved in the 2,3,7,8tetrachlorodibenzo-p-dioxin-induced signal transduction pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell line potx

Báo cáo khoa học: Protein kinase Ch activity is involved in the 2,3,7,8tetrachlorodibenzo-p-dioxin-induced signal transduction pathway leading to apoptosis in L-MAT, a human lymphoblastic T-cell line potx

... lymphoblastic T-cell line. In this report, we provide the following evidence that the protein kinase C (PKC)h activity is func-tionally involved in the AhR-independent signal transduction mechanismthat ... apoptosis in mouse spleen cells [12], can be explained by the singleAhR pathway. The molecular mechanism involved in the AhR-independent pathway(s) leading to TCDD-induced immunotoxicity is not ... PKCh) is involved in the TCDD-induced apoptosis of L-MATcells. The incubation of L-MAT cells with 20 nm TCDDresulted in morphological changes characteristic ofapoptosis upon staining with the...
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Báo cáo khoa học: A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-jB pathway in skeletal muscle pdf

Báo cáo khoa học: A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-jB pathway in skeletal muscle pdf

... binding totitin by improving the accessibility of the titin-bindingdomain. Interestingly, the importance of CARP inter-action for its function was recently demonstrated in aFig. 3. Calpain ... confirm thishypothesis. The results obtained in the present study stronglysuggest that, once cleaved, CARP interaction with the region N2A is reinforced. CARP interacts with titin-N2A using a ... analysisof CARP expression in the subcellular compartmentsobtained from the muscle of the mice injected withpYFP-CARP-CFP-HIS confirms the presence of the protein in the nucleus and on the cytoskeletal...
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Hướng dẫn khắc phục lỗi “username is not in the sudoers file...” trong Ubuntu doc

Hướng dẫn khắc phục lỗi “username is not in the sudoers file...” trong Ubuntu doc

... MUST be edited with the 'visudo' command as root. # # Please consider adding local content in /etc/sudoers.d/ instead of # directly modifying this file. # # See the man page for ... việc gì nữa, và thay vào đó hệ thống sẽ hiển thị thông báo lỗi như sau: damien is not in the sudoers file. This incident will be reported trong đó damien là tên tài khoản đang sử dụng. Trong ... phục lỗi “username is not in the sudoers file ” trong Ubuntu Ở chế độ mặc định của Ubuntu, tại khoản người dùng đầu tiên được khởi tạo trong quá trình cài đặt cũng là Administrator của hệ thống....
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Báo cáo khoa học: Myocyte enhancer factor 2B is involved in the inducible expression of NOX1⁄ NADPH oxidase, a vascular superoxide-producing enzyme ppt

Báo cáo khoa học: Myocyte enhancer factor 2B is involved in the inducible expression of NOX1⁄ NADPH oxidase, a vascular superoxide-producing enzyme ppt

... 3B). These findings clearly indicate that the MEF2-binding site between )139 and )130 is essentialfor PGF2a-induced activation of the NOX1 promoter.Binding of MEF2 to the consensus sequence in the ... II-induced chronic hypertension usingNOX1-deficient mice [19]. The basal level of the NOX1 transcript is much lower than the levels ofother NOX isoforms expressed in vascular tissue,whereas inducible ... affect the mobilityof the specific bands (lane 4, Fig. 4B). These resultssuggest that PGF2aincreases the binding of MEF2to the consensus-binding site located between )139and )130 of the NOX1...
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Báo cáo khoa học: The GxxxG motif of the transmembrane domain of subunit e is involved in the dimerization/oligomerization of the yeast ATP synthase complex in the mitochondrial membrane doc

Báo cáo khoa học: The GxxxG motif of the transmembrane domain of subunit e is involved in the dimerization/oligomerization of the yeast ATP synthase complex in the mitochondrial membrane doc

... cerevisiae (P81449, Swiss-Prot)are in bold. The numbering of the yeast sub-unit e begins at the initiating methionine. The star indicates the position of the unique cys-teine residue of the ... alanine residue was inserted after Phe18 in order todisrupt a helix–helix packing interface involving the amino-acid residues on both sides of the insertion [40]. In the othertwo mutants, the ... connecting stalks. The sector F1containing the headpiece is a water-soluble unit retaining the ability tohydrolyse ATP when in a soluble form. F0 is embedded in the membrane and is mainly composed...
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