... & Juliano, M .A. (2001) S1subsite specificity of a recombinant cysteine proteinase,CPB, of Leishmania mexicana compared with cruzain, humancathepsin L and papain using substrates containing ... Discrimination of cruzipain, themajor cysteine proteinase of Trypanosoma cruzi, and mammaliancathepsins B and L, by a pH-ind ucible fluorogenic sub strate of trypanosomal cysteine pr oteinases. ... peptidase upon transfer into the endoplasmic reticu-lum ,a1 06aminoacidpro-region ,a2 18aminoacidmaturedomain that includes the active site, and a C-terminaldomain of either 16 or 100 amino acids [7]....