... the protein surface that may lead to protein aggregation[16]. In addition, introduction of a single tyrosine intothe N-terminal region has been reported to improve thethermostability and thermophilicity ... reflected in the increased frequency of totalnumber of atoms, charged amino acids and hydrogenbonds. Another feature appears to be the increase in thenumber of residues in the b-strands. This indicates ... Nussinov, R. (2000) Factors enhancingprotein thermostability. Protein Eng. 13, 179–191.39. Turunen, O., Vuorio, M., Fenel, F. & Leisola, M. (2002)Engineering of multiple arginines into...