... sense of humour: the informationdemandsingenomicsarestaggering. The genomecontainstwokinds of digitalinformation,onethatencodes the proteinandRNA‘molecularmachines of life’,and the otherbeing the regulatorynetworksthatspecify how thesegenesareexpressedintime,spaceandamplitude.DNAinformationislayeredandarrangedinahierarchy,startingwith the gene,then the RNA, then the protein, then the protein interactions, then the proteincomplexes,then the networks of proteincomplexes ina cell,then the tissues andorgans,then the individualorganism,followedbypopulationsand the ecosystemsinwhichtheylive.Inthiskind of discovery science, masteringsuchvastquantities of informationtoanswerimportantquestionsisaskillandanart.And the hardware? The firstautomatedsequencingmachinetookaday,in1986,tosequence250 of the threebillionbasepairs.Ittook the humangenomeprojecttenyearstosequence the humangenome,twoyearsshorterthanpredicted;and the privatecompanyCelerawithitsso-calledshotgunapproachtooklessthan the publicconsortium’s ... waspreservedinArabicmanuscripts’(Lewontin1995:148).Thereisnoquestionthat the libraries of Alexandriawerecentralto the cityand the broadregionincludingwhattodayis the Middle-East,NorthAfricaandmuch of CentralandWesternEurope;thattheywerenot the onlyonestoexistbutwerepart of alargerset of institutionstoemergefrom the concatenations of cultural,scholarlyandotherareas of learningandapplication of whatwerethen the advancedsocieties of thispart of the world. The agency of theirruinisnotsocertain,neitherisitclearwhatitwasinvolumeandsubstance ... Or,perhaps,itrelatedtotradingwithneighbours,or,moreonadeeplyexistentiallevel,observing the astronomical,with,asGeorgesIfrahputsitsobeautifullyin the Universalhistory of numbers,afascinationwith the regularity of the phases of the moon, the eternalreturn of dayandnight, the cycle of the seasons’or,wemightadd,given the context, the ellipticalphases of the tides of greatandmarvellousoceans(Ifrah2000:xvi).In the history of counting, the SanandKhoiperhapsjoinedotherhumanbeingsand,inobservingthatbirdshavetwowings,animalsfourlegs,andtheytenfingerstotheirhandsandtentoestotheirfeet,developedanumberingsystemusingtheirfingersortoesas the baseten, the mostcommontype of countingfoundamongearlierpeoples.Orperhapstheyjoined the Mayans,Aztecs,CeltsandBasqueswholookeddownattheirfeetandrealisedthattheirtoescouldbecountedlikefingersandchose the muchmoreunusualarithmeticbase of 20.SCI...