... appetite regulation centers are located, and discusses the physiological actions of this peptide, particularly in relation to feeding and energy metabolism We also consider the therapeutic value of the ... occurs via the activation of orexin- and ⁄ or NPY-expressing neurons, and that long-term body weight loss is a result of the promotion of energy expenditure GALP in feeding and energy metabolism ... regions of the rat brain Injection of GALP into the third ventricle induces c-Fos expression, a marker of cell activation, in the horizontal limb of the diagonal band of Broca, POA, ARC and median...