... inflammatory response seen in the airways of COPD patients, hypothetically regulating the infiltration and the survival of inflammatory cells in the submucosa of COPD patients [48] Interestingly, leptin s ... TNF-a and leptin on Day of admission [109] sTNFR55 significantly explains 66% of the variation in energy balance in Day of the exacerbation, while leptin is excluded, suggesting that the influence ... counteractions with other cytokines and adipokines However, decoding its pulmonary impact is not an easy task, since the role of leptin cannot always be separated from obesity and the biology of adipose...