... model AFI of 2¢,5¢ d(G4C4), possesses composite features of both A and BDNA In view of these, it is perhaps appropriate to regard the structure of iso d(G4C4) as a hybrid structure of A and B forms ... winding of the 2¢,5¢ single-stranded DNA helix, compared with 3¢,5¢ DNA, probably offers restrictions to the folding abilities of even single-stranded 2¢,5¢ DNA Hence, it may be argued that topological ... modified to handle 2¢,5¢ linkages to obtain optimum geometry at the 2¢,5¢ phosphodiester linkage Ideal A- and B-type duplex models for iso DNA (possessing helical parameters identical to those of the...