Amino acids and peptides barrett, elmore, donald trevor
barrett - amino acids and peptides (cambridge, 2004)
... 1.8 ‘Non-protein amino acids , alias ‘non-proteinogenic amino acids or ‘non-coded amino acids 1.9 Coded amino acids, non-natural amino acids and peptides in nutrition and food science and in ... and then processed there Standard terminology has emerged for the extended polypeptides, pre-, pro- and prepro -peptides for the inactive N-terminal-extended, C-terminal-extended and N- and C-terminal ... present that involve the sidechain amino group of an ␣-di -amino acid (e.g lysine) or of a poly -amino acid and/ or the side-chain carboxy-group of an ␣ -amino- di- or -poly-acid (e.g aspartic acid or glutamic...
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Báo cáo khoa học: Assimilation of excess ammonium into amino acids and nitrogen translocation in Arabidopsis thaliana – roles of glutamate synthases and carbamoylphosphate synthetase in leaves ppt
... (CIT) and arginine (ARG) contents in leaves of Arabidopsis plants cultured with mM nitrate in air (F) Ornithine, citrulline and arginine contents in leaves of Arabidopsis plants cultured with mM ammonium ... play overlapping or distinct roles in nitrogen assimilation into amino acids for transport in planta using mutants decient in GLU1, GLU2, or GLT Despite the in silico data of the Arabidopsis databases, ... nitrogen into glutamine and glutamate (Fig 8) These amino acids are trafcked under the ne control of amino acid transporters [32,33] Active uptake into yeast cells suggests that the basic amino acids...
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Báo cáo y học: " Effects of carbohydrate, branched-chain amino acids, and arginine in recovery period on the subsequent performance in wrestlers" potx
... muscle and further increase glycogen recovery [13] BCAA and arginine may also facilitate the insulin-dependent phase by inducing insulin secretion [14, 15] The consumption of leucine and arginine ... Effects of carbohydrate, branched-chain amino acids, and arginine in recovery period on the subsequent performance in wrestlers Tsong-Rong Jang1, Ching-Lin Wu2, Chai-Ming Chang3, ... that consumption of carbohydrate or carbohydrate plus BCAA and arginine 15 during the recovery period had no effect on the performance in the subsequent intermittent high-intensity exercise in well-trained...
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Characterization of new peptides and physiological amino acids present in cerebrospinal fluid of chronic pain patients
... pain patients Vs Citrulline negative labor pain patients 78 3.3 Correlation between Pain intensity (PI) and the concentration of Pain related amino acids in cerebrospinal fluid of the labor pain ... nitric oxide in acute labor pain Applying our new method for amino acid analysis in CSF to analysis of physiological amino acids and other pain related molecules in the cerebrospinal fluid of pregnant ... Pain intensity and the concentration of pain related amino acids 79 3.3 CSF concentration of other amino acids not related to pain 81 Chapter 4.1 Comparison of concentration of pain- related amino...
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Báo cáo khoa học: The ATPase activities of sulfonylurea receptor 2A and sulfonylurea receptor 2B are influenced by the C-terminal 42 amino acids doc
... lacked the last 42 amino acids Figure 2A and Table show that the ATPase activity of NBD2-DC was greater than that of SUR2B but similar to that of NBD2A, favoring the idea that the last 42 amino acids ... than those for the NBDs of SUR2A [22] SUR2A and SUR2B differ only in their last 42 amino acids, which not form part of the catalytic site Thus, these amino acids may interact with the NBDs to modulate ... (site and site 2) that comprise the Walker A and Walker B motifs of one NBD and the linker domain of the other In the absence of Mg2+, there is little difference in ATP block of Kir6.2 ⁄ SUR2A and...
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Báo cáo khoa học: Amino acids Thr56 and Thr58 are not essential for elongation factor 2 function in yeast potx
... compilation ª 20 07 FEBS 529 5 Role of Thr56 and Thr58 for eEF2 function in yeast 14 15 16 17 18 19 20 21 22 23 24 25 26 G Bartish et al protein that is resistant to diphtheria toxin J Biol Chem 26 8, 8665–8668 ... Journal 27 4 (20 07) 528 5– 529 7 ª 20 07 The Authors Journal compilation ª 20 07 FEBS G Bartish et al Role of Thr56 and Thr58 for eEF2 function in yeast Fig Comparison of the amino acid context surrounding ... wild-type as well as mutant forms of eEF2 FEBS Journal 27 4 (20 07) 528 5– 529 7 ª 20 07 The Authors Journal compilation ª 20 07 FEBS 529 1 Role of Thr56 and Thr58 for eEF2 function in yeast G Bartish et al...
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Báo cáo khoa học: Amino acids at the N- and C-termini of human glutamate carboxypeptidase II are required for enzymatic activity and proper folding pptx
... the contribution of the N- and C-terminal regions of GCPII to its enzymatic properties and structure /folding The results clearly show that the amino acids at the extreme C-terminus of GCPII are ... ATTCTCGAGTCATTAGGCTACTTCACTCAAAG AAACTCGAGAGATCTAAATCCTCCAATGAAGC ATTCTCGAGTCATTATGCAACATAAATCTGTCTCTT AAACTCGAGAGATCTAAATCCTCCAATGAAGC AAACTCGAGTTATTATTCAATATCAAACAGAG AAAAGATCTAAAGCATTTTTGGATGAATTG ATTCTCGAGTCATTAGGCTACTTCACTCAAAG ... the length of an epitope attached The sequence at the N-terminus of the protein was also shown to be required for the activity and/ or secretion of the GCPII carboxypeptidase As for the N-terminally...
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Báo cáo khoa học: Transport of taurocholate by mutants of negatively charged amino acids, cysteines, and threonines of the rat liver sodium-dependent taurocholate cotransporting polypeptide Ntcp docx
... is involved in taurocholate transport of the human isoform [21] We therefore looked for the role of each of the eight cysteines of the rat Ntcp for taurocholate transport Finally, threonines, within ... conserved negatively charged amino acids and cysteines Tagging of Ntcp mutants by the FLAGÒ motif To determine whether the wild-type and the mutant proteins are expressed and located on the surface of ... ¨ Point and deletion mutants of the rat liver Ntcp cDNA clone prLNaBA [1] were generated by site-directed mutagenesis by the use of the QuikChangeTM kit from Stratagene, La Jolla, USA The primers...
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Báo cáo Y học: Amino acids 3–13 and amino acids in and flanking the 23FxxLF27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor pdf
... subdomain AR3)13 in N/C interaction and the role of individual amino acid residues in and flanking the 23 FQNLF2 7motif in AR16)36 in N/C interaction Yeast protein interaction assays indicated that AR3)13 ... E., Brinkmann, A.O & Trapman, J (1997) Functional in vivo interaction between the amino- terminal, transactivation domain and the ligand binding domain of the androgen receptor Biochemistry 36, ... ligand-dependent interaction between AR NTD and AR LBD, N/C interaction, was studied in yeast and mammalian in vivo protein interaction systems, and in Ó FEBS 2002 Interaction between androgen receptor subdomains...
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Báo cáo khoa học: Arg143 and Lys192 of the human mast cell chymase mediate the preference for acidic amino acids in position P2¢ of substrates pdf
... strong preference for acidic amino acids at position P2¢ of the substrates Table P2¢ specificity and amino acids found in positions 40, 143 and 192 of nine different chymases Chymase P2¢ specificity ... alone or in cooperation with Lys192 mediates the preference for acidic amino acids at position P2¢ In the present study, we tested the roles of Arg143 and Lys192 as P2¢ specificity-determining residues ... 6% of the sequences Thus, Arg143 and Lys192 contribute almost equally to the P2¢ specificity of HC Mutating either of the two basic amino acids in these positions partially disrupts the acidic P2¢...
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Báo cáo khoa học: Chromophore attachment in phycocyanin Functional amino acids of phycocyanobilin – a-phycocyanin lyase and evidence for chromophore binding doc
... P5 and P2 for cpcE(4 2–2 76), P1 and P6 for cpcE( 1–2 72), P1 and P7 for cpcE( 1–2 74), P1 and P8 for cpcE( 1–2 37), P9 and P4 for cpcF(2 1–2 13), P10 and P4 for cpcF(1 0–2 13), P3 and P11 for cpcF( 1–1 60), ... (1988) In vitro attachment of bilins to apophycocyanin Specific covalent adduct formation at cysteinyl residues involved in phycocyanobilin binding in C -phycocyanin J Biol Chem 263, 1834 3–1 8349 ... rigid conformation in the a-CPC binding site There are 19 arginines, 13 lysines, three histidines and two tryptophans in CpcE, and 13 lysines, 10 arginines, one tryptophan and no histidine in CpcF...
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Báo cáo y học: " Albumin dialysis improves hepatic encephalopathy and decreases circulating phenolic aromatic amino acids in patients with alcoholic hepatitis and severe liver failure" doc
... of albumin dialysis in significantly modifying the amino acid profile in primary biliary cirrhosis patients with bilirubin, prothrombin index and albumin levels within normal ranges may sustain ... Fischer index, severity alcoholic hepatitis and bilirubin decrease after albumin dialysis Fischer index, severity ofof alcoholic hepatitis and bilirubin decrease after albumin dialysis Fischer index ... hepatic encephalopathy improved in all cases • Total amino acid and phenolic aromatic amino acids diminished and the Fischer ratio increased in patients with alcoholic hepatitis treated with MARS...
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Iron(III) and copper(II) complexes bearing 8 quinolinol with amino acids mixed ligands synthesis, characterization and antibacterial investigation
... Res 39, 721–7 28 Iron(III) and copper(II) complexes bearing 8- quinolinol with amino- acids mixed ligands Eddie, L.C., Christa, S., Knight, D.A., 2010 Cobalt complexes as antiviral and antibacterial ... Synthesis of the metal complexes (4a–d) Iron(III) and copper(II) complexes bearing 8- quinolinol with amino- acids mixed ligands 745 0.5 χmT / cm3Kmol -1 0.4 0.3 0.2 0.1 0.0 20 40 60 80 100 T/K Figure ... Iron(III) and copper(II) complexes bearing 8- quinolinol with amino- acids mixed ligands 743 aeruginosa (ATCC2 785 3) of 43 mm at 10 lg/ml signalling its...
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Bioinformatic analysis of bacterial and eukaryotic amino terminal signal peptides
... Post-translocation function and degradation of cleaved SPs In spite of the improved understanding of the secretory machineries and mechanisms, our understanding of the fate of SPs upon its coup de ... (Brusic, 2007) 1.2 Aims of Thesis The goal of this thesis is to contribute to the understanding of the factors that govern the substrate specificity of SPs by means of bioinformatic and molecular modeling ... known as signal peptides or “targeting signals” and the superb coordination of the translocation apparatuses (Dalbey and von Heijne, 2002) There are different classes of targeting signals that...
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