... histological, biochemical, genetic and demographic markers that may further predict the outcome of HCV infections Figure Natural History of HCV Infection Extrahepatic Manifestations Chronic HCV infection ... patients not clear the virus by months, and chronic hepatitis develops The rate of chronic HCV infection is affected by many factors, including the age at time of infection, gender, ethnicity, and ... N.H, et al Association of hepatitis C virus- specific CD8+ T cells with viral clearance in acute hepatitis C J Infect Dis, 2000 181(5): 1528-36 29 Lechner F, et al Analysis of successful immune...