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Exhaled nitric oxide measurement in asthma

Báo cáo y học:

Báo cáo y học: " Diagnosing asthma in general practice with portable exhaled nitric oxide measurement – results of a prospective diagnostic study" ppsx

... history, physical examination, bodyplethysmography and bronchial provocation results Data Analysis Baseline data is presented descriptively Two-by-two contingency tables of FENO values vs asthma ... diagnosing severe asthma has already been demonstrated [3] In mild asthma in particular, an airway obstruction is often not present, thus leading to diagnostic uncertainty Serial peak-flow measurement ... sensitivity analyses showed that the cut-off point of FENO remained the same when actually non-smoking patients initially labelled as COPD or overlap were classified as asthma patients with fixed airway...
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Báo cáo y học:

Báo cáo y học: " ''''Diagnosing Asthma in General Practice with Portable Exhaled Nitric Oxide Measurement – Results of a " pps

... say "FENO £16 ppb", "8 1% (95% CI 6 4–9 1 )" should say "8 2% (95% CI 7 2– 90 )" and "3 4" should say "6 8" In line 3, "FENO £12 ppb" should say "FENO £16 ppb" and "five" should say "three" In line "1 2 ... £1 6" In the second paragraph, in line 1, "five" should say "three" In line 5, "1 6 patients had FENO £12 ppb" should say "3 7 patients had FENO £ 16 ppb" Also in line 5, "three" should say "two" and ... 6 3–8 9 )" In line 6, "1 6 (15.8% )" should say "3 7 (36.6% )", "FENO £12 ppb" should say "FENO £16 In the Discussion section, in line 4, "8 1 %" should say "8 2 %" and in line 5, "FENO £1 2" should say "FENO...
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Báo cáo y học:

Báo cáo y học: " Exhaled nitric oxide and clinical phenotypes of childhood asthma" docx

... proximal and distal airway nitric oxide categories Respir Res 2010, 11:47 doi:10.1186/1465-9921-12-65 Cite this article as: Mahut et al.: Exhaled nitric oxide and clinical phenotypes of childhood ... asthma, showing that exhaled NO does help to describe a clinically useful phenotype despite its ability to describe underlying pathophysiology (inflammation and modified airway smooth muscle function) ... clinical and physiological correlates of exhaled NO, and the degree of FENO variance explained by the correlates The second approach used a more complex statistical tool, namely cluster analysis,...
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Báo cáo y học:

Báo cáo y học: " Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics" docx

... exhaled nitric oxide and exhaled 8-isoprostanes by body mass index in adults with asthma [See additional file: figure keys] Association of exhaled nitric oxide and exhaled 8-isoprostanes by body ... exhaled 8-isoprostanes by body mass index in healthy non-asthmatic adults Figure Association of exhaled nitric oxide and exhaled 8-isoprostanes by body mass index in healthy non-asthmatic adults [See ... leptin and adiponectin with levels of exhaled NO and exhaled 8-isoprostanes in subjects with stable asthma and healthy controls In subjects with asthma, BMI and the systemic leptin/adiponectin...
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Báo cáo y học:

Báo cáo y học: " Exhaled nitric oxide and urinary EPX levels in infants: a pilot study" potx

... Simpson, LA Lowe, A Woodcock, A Custovic, National Asthma Campaign Manchester Asthma and Allergy Study G, Urinary eosinophilic protein X, atopy, and symptoms suggestive of allergic disease at years ... dampness, measured as windowpane condensation Measuring FeNO by the present method may be an interesting non-invasive way of evaluating early inflammation in the airways Page of 8 Acknowledgements ... the sanitary towel In our own analysis of five healthy volunteers, we found a marked decrease in urinary EPX/ c levels after incubation of urine in the sanitary towel However, this systematic...
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Báo cáo khoa học: Transport of L-arginine and nitric oxide formation in human platelets pdf

Báo cáo khoa học: Transport of L-arginine and nitric oxide formation in human platelets pdf

... that platelet L-arginine transport mainly Fig L-Arginine uptake in the presence or absence of Na+ in the external medium L-Arginine uptake was measured in washed platelets (2.0 · 108 platelets) ... Characterization of the L-arginine/ nitric oxide pathway in human platelets Br J Pharmacol 101, 325–328 Radomski, M.W., Palmer, R.M & Moncada, S (1990) An L-arginine/ nitric oxide pathway present in human platelets ... · 108 platelets per for the system y+ Ó FEBS 2003 Arginine transport and NO formation in platelets (Eur J Biochem 270) 2009 Fig L-Arginine efflux in human platelets Platelets (1.0 · 109 platelets) ,...
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Báo cáo khoa học:

Báo cáo khoa học: "Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis" pdf

... the Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomelitis 13 appropriate biotinylated second antibody and the avidinbiotin peroxidase ... der Valk, P Immunocytochemical characterization of the expression of inducible and constitutive isoforms of nitric oxide synthase in demyelinating multiple sclerosis J Neuropathol Exp Neurol ... The increased expression of NT during the peak stage of EAE suggests that peroxynitrite or NO is generated in the autoimmune spinal cord lesions Fig Immunostaining of three isoforms of NOS in...
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Báo cáo khoa học:

Báo cáo khoa học: "Immunohistochemical study of constitutive neuronal and inducible nitric oxide synthase in the central nervous system of goat with natural listeriosis" potx

... counterstained with hematoxylin Magnification A and B, ×66 C and D, ×132 Immunohistochmical study of nitric oxide synthase in the central nervous system of goat Enhanced expression of nNOS and iNOS in ... is the first study of NOS expression in the goat brain with listeriosis The involvement of iNOS in bovine and caprine listeriosis has been reported previously, and the increased expression of iNOS ... microabscesses, and some astrocytes (identical in Fig Histology and immunostaining of caprine brains with natural listeriosis A: Brain of a goat with listeriosis showing meningoencephalitis H-E staining,...
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Báo cáo khoa học:

Báo cáo khoa học: " A novel b-glucan produced by Paenibacillus polymyxa JB115 induces nitric oxide production in RAW264.7 macrophages" docx

... conducted to examine the potential use of the novel β-glucan purified from P polymyxa JB115 as an immunostimulant or as an adjuvant of some animal vaccines β-glucan-induced nitric oxide production ... by β-glucan (Fig 4) Finally, the mRNA expression of various cytokines was investigated in RAW264.7 macrophages which were exposed to β-glucan or LPS P polymyxa JB115 β-glucan induced mRNA expressions ... Polysaccharides isolated from Phellinus baumii stimulate murine splenocyte proliferation and inhibit the lipopolysaccharide-induced nitric oxide production in RAW264.7 murine macrophages World...
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Báo cáo y học:

Báo cáo y học: "Effect of allergen-specific immunotherapy with purified Alt a1 on AMP responsiveness, exhaled nitric oxide and exhaled breath condensate pH: a randomized double blind study" ppsx

... weal was ≥3 mm larger in diameter than that of the glycerinated saline Data analysis An intention-to-treat approach was followed in the analysis of efficacy data All patients with a baseline and ... profile of SIT with Alt a1 is superior to that detected with a conventional standardized extract of Alternaria Conclusions Although SIT with Alt a1 is well tolerated and induces an allergen-specific ... placebo-controlled study of Alternaria alternata immunotherapy: Clinical efficacy and safety Pediatr Allergy Immunol 2008, 19:67-75 Asturias JA, Ibarrola I, Ferrer A, Andreu C, Lopez-Pascual...
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Báo cáo y học:

Báo cáo y học: "Ex vivo effects of flavonoids extracted from Artemisia herba alba on cytokines and nitric oxide production in Algerian patients with Adamantiades-Behcet''''s disease" pptx

... medicinal plant Artemisia herba alba on Th1 and Th2 cytokines and nitric oxide production Methods: The modulatory effects of flavonoùds extracted from Artemisia herba alba on cytokines and nitric ... Ex vivo effects of flavonoùds extracted from Artemisia herba alba on cytokines and nitric oxide production in Algerian patients with Adamantiades-Behỗets disease ... disturbed cytokines production in ABD Such dysregulation in cytokine release contributes to the regulation of several enzymes such as the inducible nitric oxide (NO) synthase (iNOS) The function of...
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Báo cáo y học:

Báo cáo y học: "Gender-based reciprocal expression of transforming growth factor-β1 and the inducible nitric oxide synthase in a rat model of cyclophosphamide-induced cystitis" ppsx

... TGF-β1 in the urine of male rats after CYP were also significantly higher than the levels of active and total TGF-β1 in the urine of female rats, both at baseline and after CYP (ANOVA, Tukey post ... control rats collected at the same time point of the day The levels of NO2-/NO3- in the urine of CYP-treated female rats remained higher as compared to both CYP-treated and control male rats (ANOVA, ... (panel A) was maintained across all groups The substantial levels of latent TGF-β1 in female rats at baseline and after CYP was accompanied by only minor levels of active TGF-β1 in bladder tissue...
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Báo cáo y học:

Báo cáo y học: " The anti-inflammatory effects of the tellurium redox modulating compound, AS101, are associated with regulation of NFB signaling pathway and nitric oxide induction in macrophages" doc

... as: Brodsky et al.: The anti-inflammatory effects of the tellurium redox modulating compound, AS101, are associated with regulation of NFB signaling pathway and nitric oxide induction in macrophages ... kinetics I At h, AS101 probably enters the nucleus and may interfere with the DNA-binding ability of the NFB complex resulting in the inhibition of iNOS expression Because tellurium readily ... modifying specific cysteine residues in IKKa and in the p50-subunit resulting in the inhibition of nuclear translocation and DNA-binding to the iNOS promoter Nevertheless these effects are exerted...
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