... Madrid, L.V., Mayo, M.W., Reuther, J.Y & Baldwin, A. S Jr (2001) Akt stimulates the transactivation potential of the RelA/ p65 subunit of NF-kappa B through utilization of the Ikappa B kinase and ... PKA activation does not affect IjB degradation nor DNA-binding activity of NF-jB PKA impairs transactivation potential of p65 In the unstimulated cells, NF-jB is sequestrated in the cytoplasm as ... that the cAMP/ PKA signaling pathway inhibits transcriptional activity of NF-jB Although a previous report by others [22] suggested that PKA inhibited NF-jB activation by stabilizing IjB, PKA activating...