... the symptomatology of patients and the nature of the reparative tissue Asymptomatic patients developed predominantly hyaline tissue in a highly significant percentage of cases, while symptomatic ... tissue that, in time, differentiates and becomes organized into hyaline tissue with cells in columns Figure obtained from asymptomatic patients only Histological and immunohistochemical analysis data ... characteristics biopsy with hyaline characteristics taken 14 months after Hyalograft® C Autograft implantation (a) H & E and eosin staining (b) Glycosaminoglycan (safranin-O) staining (c) Collagen type I (immunohistochemistry)...