... Ser146 in the numbering of the intact CA) The CACW40A protein is monomeric, and its structure is similar to that of the subunits in the dimeric, non-mutated CAC, but, in the monomeric form, the segment ... responsible, from a thermodynamic point of view, for the binding of the monomeric species of CAC? We have previously discussed the variation in the free energy of binding as a function of the changes ... dimerization domain of the HIV-1 capsid protein Science 278, 849–853 23 Worthylake DK, Wang H, Yoo S, Sundquist WI & Hill CP (1999) Structures of the HIV-1 capsid protein ˚ dimerization domain at...