... DRS -DA4, DRS -B2, DDK, and DRS-L1 Hexagonal and round backgrounds refer to basic and acid amino acids respectively, pentagonal backgrounds to hydrophilic residues, and squares to hydrophobic residues ... peptides as antibiotics and immunomodulatory molecules [3,42,43] Modification of DRSDA4 to enhance its direct bactericidal effect and to extend its antibacterial activity to Gram-positive strains, ... herein the isolation and characterization of a new dermaseptin- related peptide, GMWSKIKNA GKAAKAAAKAAGKAALGAVSEAM, named dermaseptin DA4 (DRS-DA4), according to the new dermaseptin nomenclature...