... study design, acquisition of data, analysis and interpretation of data, and statistical analysis M-JB and FA contributed to acquisition of data and to analysis and interpretation of data DC and ... Zhang Y, Niu J, Goggins J, Amin S, LaValley MP, Guermazi A, Genant H, Gale D, Felson DT: Increase in bone marrow lesions associated with cartilage loss: a longitudinal magnetic resonance imaging ... played by the meniscal structure and positioning in protecting the integrity of cartilage in both healthy and OA individuals Our data, however, clearly point to the fact that by far the greatest...