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Nanoparticles of biodegradable polymers for delivery of diagnostic therapeutic agents their potential application in brain cancer therapy

Nanoparticles of biodegradable polymers for delivery of diagnostic therapeutic agents their potential application in brain cancer therapy

Nanoparticles of biodegradable polymers for delivery of diagnostic therapeutic agents their potential application in brain cancer therapy

... NANOPARTICLES OF BIODEGRADABLE POLYMERS FOR DELIVERY OF DIAGNOSTIC/ THERAPEUTIC AGENTS: THEIR POTENTIAL APPLICATION IN BRAIN CANCER THERAPY YU QIANRU (B.Eng, Southeast ... Limitations in Modern Chemotherapy 2.2 Brain Cancers and Blood Brain Barrier (BBB) 2.2.1 Brain cancers and cancer treatment 2.2.2 Introduction to the blood brain barrier 2.2.2.1 History of blood brain ... the delivery of therapeutic agents into the brain Paclitaxel, one of the most widely used anti -cancer drugs, has limited application in treating brain tumor because of the existence of BBB Of...
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Nanoparticles of biodegradable polymers for delivery of therapeutic agents and diagnostic sensitizers to cross the blood brain barrier (BBB) for chemotherapy and MRI of the brain

Nanoparticles of biodegradable polymers for delivery of therapeutic agents and diagnostic sensitizers to cross the blood brain barrier (BBB) for chemotherapy and MRI of the brain

... Functions of the Blood Brain Barrier The main function of the blood brain barrier is to protect the brain The BBB serves as an impermeable wall to prevent the entry of agents from outside of the brain ... Anatomy of the Blood Brain Barrier 1.1.2 Functions of the Blood Brain Barrier 1.1.3 Clinical Significance of the Blood Brain Barrier 1.2 METHODS TO OVERCOME THE BLOOD BRAIN BARRIER 1.3 NANOPARTICLES ... polymers to deliver drugs across the blood brain barrier and the surface coating plays key roles in determining the extent of the particles to cross the BBB To further investigate the potential for the...
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Nanoparticles of biodegradable polymers for controlled and targeted delivery of protein drugs and small molecule drugs

Nanoparticles of biodegradable polymers for controlled and targeted delivery of protein drugs and small molecule drugs

... NANOPARTICLES OF BIODEGRADABLE POLYMERS FOR CONTROLLED AND TARGETED DELIVERY OF PROTEIN DRUGS SMALL AND MOLECULE DRUGS BY LEE SIE HUEY (B.Sc (Hons.), NUS) A THESIS SUBMITTED FOR THE DEGREE OF ... backbone of PLA and PLGA to form PLA-TPGS and PLGA-TPGS block copolymers These block copolymers are an example of amphiphiles Their uses as different carriers for delivery of protein and anticancer ... Peptide /protein drug delivery 15 2.2.1 Structural aspect of protein 15 2.2.2 Challenges in peptide /protein drug delivery 17 2.2.3 Approaches for delivery of peptide /protein drugs...
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Nanomedicine  multifunctional nanoparticles of biodegradable polymers for cancer treatment

Nanomedicine multifunctional nanoparticles of biodegradable polymers for cancer treatment

... NANOMEDICINE: MULTIFUNCTIONAL NANOPARTICLES OF BIODEGRADABLE POLYMERS FOR CANCER TREATMENT LIU YUTAO (B.Sc., Fudan University) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... development of cutting-edge nanoparticles of biodegradable polymers with overall fascinating performance demonstrates the progress in the field of nanomedicine for cancer treatment viii NOMENCLATURE ... 173 LIST OF PUBLICATIONS 193 vi SUMMARY Multifunctional nanocarriers have been regarded as potent candidates for efficient cancer nanomedicine Nanoparticles of biodegradable polymers...
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Multifunctional nanoparticles of biodegradable polymers for diagnosis and treatment of cancer

Multifunctional nanoparticles of biodegradable polymers for diagnosis and treatment of cancer

... MULTIFUNCTIONAL NANOPARTICLES OF BIODEGRADABLE POLYMERS FOR DIAGNOSIS AND TREATMENT OF CANCER PAN JIE (M ENG., TIANJIN UNIVERSITY) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... nanoparticles of biodegradable polymers for QDs formulation for targeted and sustained imaging for cancer diagnosis at its early stage Two polymers of poly(lactide)-vitamin E TPGS (PLA-TPGS) and vitamin ... loading QDs for targeted and sustained imaging for cancer diagnosis at its early stage 4) to prepare biodegradable polymeric multifunctional nanoparticles for targeted chemotherapy and imaging...
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Trastuzumab decorated nanoparticles of biodegradable polymers for targeted small molecule chemotherapy

Trastuzumab decorated nanoparticles of biodegradable polymers for targeted small molecule chemotherapy

... (PLGA/MMT) nanoparticles decorated by trastuzumab for targeted chemotherapy of breast cancer Biomaterials 2008; 29(4): 475-486 Sun B, Feng SS Trastuzumab decorated nanoparticles for targeted chemotherapy ... conjugation of trastuzumab on NP surface for targeted drug delivery Experiments were carried out to investigate the feasibility of the obtained NPs for targeted delivery of small molecule drugs The trastuzumab ... objective of this research is to study the effectiveness of two systems of trastuzumabfunctionalized nanoparticles for targeted drug delivery In the first part, a novel system of trastuzumab- decorated...
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Paclitaxel loaded nanoparticles of biodegradable polymers for cancer chemotherapy

Paclitaxel loaded nanoparticles of biodegradable polymers for cancer chemotherapy

... PACLITAXEL LOADED NANOPARTICLES OF BIODEGRADABLE POLYMERS FOR CANCER CHEMOTHERAPY KHIN YIN WIN (M Sc., NUS) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF CHEMICAL ... potential analysis of various formulations of paclitaxel- loaded PLGA nanoparticles 81 Figure 13 XRD analyses of paclitaxel, TPGS, blank PLGA nanoparticles and paclitaxel- loaded PLGA nanoparticles ... of paclitaxel- loaded PLGA nanoparticles, fluorescent PLGA nanoparticles and standard PS nanoparticles 133 Table Surface chemistry of the formulation materials and the paclitaxel- loaded PLGA nanoparticles...
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Nanoparticles of biodegradable polymers for gene therapy of hepatitis b

Nanoparticles of biodegradable polymers for gene therapy of hepatitis b

... DNA: NANOPARTICLES < /b> OF < /b> BIODEGRADABLE < /b> POLYMERS < /b> FOR < /b> GENE < /b> THERAPY < /b> OF < /b> HEPATITIS < /b> B JUNPING WANG (B Eng., ZJU, China) A THESIS SUBMITTED FOR < /b> THE DEGREE OF < /b> MASTER OF < /b> SCIENCE GRADUATE PROGRAM IN BIOENGINEERING ... gastrointestinal (GI) barrier and blood brain barrier, thus can benefit oral gene < /b> delivery and brain gene < /b> delivery vii LIST OF < /b> FIGURES AND TABLES Fig.2.1 Basic components of < /b> cationic lipids (DC-Chol) ... most of < /b> the current polymers < /b> for < /b> gene < /b> delivery Finally, the author discussed the application of < /b> biodegradable < /b> nanoparticles < /b> for < /b> gene < /b> delivery which is viewed as the most promising field for < /b> current...
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Báo cáo vật lý:

Báo cáo vật lý: "Synthesis and Characterization of Bismuth Tantalate Binary Materials for Potential Application in Multilayer Ceramic Capacitors (MLCC)" doc

... Pellets of single phase sample were prepared using a stainless steel die measuring mm in diameter Sufficient amount of powder was added, cold pressed uniaxially, and sintered at 1100oC in order to increase ... its volatile, reactive characteristic and relatively low firing temperature in forming binary or ternary materials with other elements, e.g bismuth vanadates, bismuth niobates or even structurally ... satisfies the trend of miniaturization and high functionality of modern electronic devices as green ceramic tapes of different materials serving different passive functions are laminated and co-fired...
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Báo cáo y học:

Báo cáo y học: "Down-regulation of kallikrein-related peptidase 5 (KLK5) expression in breast cancer patients: a biomarker for the differential diagnosis of breast lesions" doc

... forward 5 -CCGGTGACAAAGCAGGTAGAG-3’ and reverse 5 -GTGAACTTGCAGAGGTTCGTGTA-3’ pair of primers, whereas the use of the HPRT1 forward 5 TGGAAAGGGTGTTTATTCCTCAT-3’ and reverse 5 -ATGTAATCCAGCAGGTCAGCAA-3’ ... study, the analysis and the interpretation of the data, the statistical analysis and supervised the study All authors read and approved the final manuscript Page 10 of 11 Avgeris et al Clinical ... acquisition, the analysis and the interpretation of the data AP participated in the conception and design of the study and the acquisition of the data AS participated in the conception and design of the...
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Báo cáo khoa học: Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heart potx

Báo cáo khoa học: Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heart potx

... saturation of the two isoenzymes of OGDH with 2-oxoglutarate Discussion Identification of novel OGDH isoform and its implication in brain metabolism Distinguishing proteins with highly similar ... analysis predicting it to be a novel OGDH isoenzyme [16], the protein has not been reported in mammalian mitochondrial proteomes [17–19] We show that the presence in brain of the novel isoenzyme of ... differences in the supramolecular organization of OGDHC isolated from heart and brain Saturation of brain OGDHC with 2-oxoglutarate Kinetic analysis of the dependence of the overall activity of brain...
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Báo cáo hóa học:

Báo cáo hóa học: " Multiplexed methylation profiles of tumor suppressor genes and clinical outcome in lung cancer" potx

... participated in acquiring clinical samples and follow-up clinical information MSC participated in study design and coordination, data analysis and interpretation and final writing of the manuscript ... suppressor genes could be methylated in lung cell lines and tumors Next, we determined whether the methylation status of such genes could contribute for lung tumor stratification and clinical outcome ... panel of candidate genes selected could be appropriate to detect aberrant methylation profiles in human lung tumors MS-MLPA profiles for clinico-histopathologic stratification of lung tumors In...
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Báo cáo sinh học:

Báo cáo sinh học: " Research Article Estimation of Time-Varying Coherence and Its Application in Understanding Brain Functional Connectivity" potx

... perspective into the characteristics of time-varying spectrum via studying the properties of the corresponding kernel However, to maintain physical meaningness in time-varying spectrum and coherence, ... normalization of the time-varying cross spectrum The time-varying coherence certainly inherits the characteristics of the time-varying spectra Therefore, the multiscale characteristic of the ST-spectrogram ... ST-spectrogram in studying the time-varying characteristic of time series, we estimate the time-varying spectra and coherence of a pair of synthetic nonstationary time series using both the GTand the...
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Báo cáo nghiên cứu khoa học:

Báo cáo nghiên cứu khoa học: "STUDY ON THE ANTIBACTERIAN CHARACTERISTICS OF TEA TREE OIL AND ITS APPLICATION IN COSMETICS" ppt

... composition points out that beside terpinen-4-ol, other components in the tea tree oil have also the added effect of antibacterium 3.3.Investigation of tea tree oil application in cosmetics Since tea ... also other components in the tea tree oil have the antibacterial effect - The accepted dose of all fractions of the tea tree oil in practical use is 0.25% - By adding 1% of the emulsifying reagent ... effect of essential oil evaporation by contacting the agar medium with the essential oil vapor is shown in Table It has pointed out that only the diffusion of the oil determines the antibacterial characteristics...
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Báo cáo khoa học:

Báo cáo khoa học: "Evaluation of clinical, laboratory and morphologic prognostic factors in colon cancer" ppsx

... (11.9%), in ascending colon of 14 patients (15.2%), in transverse colon of subjects (8.7%), in hepatic flexure of patients (8.7%), in splenic flexure of patients (7.6%), in descending colon of 10 ... resection and type of operation are important prognostic factors In a recent Table 2: Results of multivariate analysis of clinical and laboratory data of patients with colon cancer Source Main effects ... Results of univariate analyses of clinical, laboratory and pathomorphologic data considering pT staging as independent parameter Source Sum of squares Df Mean Square R-ratio P-value pT staging vs...
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Từ khóa: biodegradable polymers for the engineering and regeneration of different tissuesenzyme immobilization in biodegradable polymers for biomedical applicationsbiodegradable polymers for guided nerve regenerationimplications for™the design of novel therapeutic agents for™psychiatric disordersevaluation of treatment related toxicity and clinical outcome in lung cancer treated by image guided radiotherapy and chemotherapycellular targets of e6 and their potential role in hmec immortalizationinvestigation of acquired resistance to egfr targeted therapies in lung cancer using cdna microarraysthe discovery of zinc fingers and their practical applications in gene regulation a personal accounta tool for creating pseudo 3d spaces with hyperphoto an application in ethnographic studiesdesign and development of polymers for gene deliverydesign and development of polymers for gene delivery pdfpoly alkyl cyanoacrylate nanoparticles for delivery of anti cancer drugsmanual of diagnostic tests for aquatic animals 2009manual of diagnostic tests for aquatic animals 2013manual of diagnostic tests for aquatic animalsBáo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Báo cáo quy trình mua hàng CT CP Công Nghệ NPVMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ