... information on family history of asthma and allergy, as well as maternal smoking habits At ages 1, 2, 4, 10 and 18 years, the original questionnaire-based information was updated, a study investigator ... IgE screen at age 10, and with skin prick test positivity at ages 4, 10 and 18 years Univariable analysis Univariable analysis showed no significant association between birth order and IgE (serum ... in the interaction terms were IL13 polymorphisms and birth order Outcome variables include skin prick tests at ages 4, 10, and 18, total IgE at birth (cord serum) and at age 10, and inhalant IgE...