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Multimodal tumor imaging by iron oxides and quantum dots formulated in poly (lactic acid) d alpha tocopheryl polyethylene glycol 1000 succinate nanoparticles

Tài liệu Activity Data on Fundraising, Investments and Divestments by Private Equity and Venture Capital Firms in Europe 2012 ppt

Tài liệu Activity Data on Fundraising, Investments and Divestments by Private Equity and Venture Capital Firms in Europe 2012 ppt

... raising/managing the fund (“industry statistics”) • The funds included in the statistics are: private equity funds making direct private equity investments, mezzanine private equity funds, co-investment ... has collected data directly from associations’ members and participants in the other countries in Europe Version Presentation as of 9/5 /2012 Disclaimer The information contained in this report ... (manufacturing companies) or deliver non-financial services • Later-stage fund: A venture capital fund focused on investing in later-stage companies in need of expansion capital • • Balanced fund: A venture...
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Báo cáo khoa học: Inhibition of an iron-responsive element/iron regulatory protein-1 complex by ATP binding and hydrolysis docx

Báo cáo khoa học: Inhibition of an iron-responsive element/iron regulatory protein-1 complex by ATP binding and hydrolysis docx

... b-mercaptoethanol We demonstrate a requirement for ATP hydrolysis in order to inhibit recombinant IRP-1 binding activity, and both ATP and ADP suppress binding (Fig 3) The mechanism of activation of IRP-1 ... 8-azido-[32P ]ATP[ aP], together with evidence of binding of [32P ]ATP[ aP] but not [32P ]ATP[ cP] in the filter assay (data not shown), is a strong indication of an ATPase activity of IRP-1 Competition by ATP and ... Software, San Diego, CA) Acknowledgements This work was supported by grants from the Heart and Stroke Foundation of Canada (grant T4134) and the Canadian Institutes of Health Research (grant MT11270)...
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Báo cáo khoa học: Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells ppt

Báo cáo khoa học: Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells ppt

... from oxidation enhances, rather than inhibits, their induction of lipid accumulation in macrophages The enhancement of lipid accumulation in macrophages by CRLPs containing probucol and lycopene ... Effect of pCRLPs on lipid synthesis in THP-1 macrophages The effects of CRLPs and pCRLPs on lipid synthesis in THP-1 macrophages were investigated by measuring the incorporation of [3H]oleate into ... induction of lipid accumulation in the cells by the particles is enhanced when they are protected from oxidation, we investigated the mechanism of this effect by comparing the in uence of CRLPs and...
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Báo cáo khóa học: Large aggregating and small leucine-rich proteoglycans are degraded by different pathways and at different rates in tendon pot

Báo cáo khóa học: Large aggregating and small leucine-rich proteoglycans are degraded by different pathways and at different rates in tendon pot

... and 2) is indicated in the elution profiles in the total volume of the column The percentage of 35S-labelled large and small proteoglycans remaining in the matrix at various times after incubation ... Sulfate-free medium was used in order to increase the incorporation of [35S]sulfate into proteoglycans as it has previously been reported that the rate of incorporation of [35S]sulfate into proteoglycans ... processing of decorin core protein was shown by the presence of additional distinct bands at 25 kDa and below (lanes ii and iii) These observations indicate that degradation of core proteins of...
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Ele ctricity Use d by Office Equipment and Netw ork Equipment in the U.S.: Detailed Report and A ppendices ppt

Ele ctricity Use d by Office Equipment and Netw ork Equipment in the U.S.: Detailed Report and A ppendices ppt

... of paper used and then allocate this total based on professional judgment and anecdotal data on typical imaging and paper use rates We use this approach, relying on a mixture of data cited from ... origin of the data We did not separately estimate uncertainty in commercial input data and industrial input data Tables A- 27 and A- 28 show our estimates of the range of uncertainty in commercial/industrial ... external discs and tape drives are not included in CPUs mainframes at 10 kW We also assumed that CPUs of minicomputers and mainframes are always on but their associated peripherals are off at night...
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báo cáo hóa học:

báo cáo hóa học: " Relationship between oxygen supply and cerebral blood flow assessed by transcranial Doppler and near – infrared spectroscopy in healthy subjects during breath – holding" doc

... provide oxygen during both resting condition and focal cortical activity The strict coupling existing between "activation", local oxygen consumption, and increased regional cerebral blood flow constitutes ... is maintained and then quickly recovers baseline conditions after breath release NIRS recordings Changes in the concentrations of O2Hb and CO2Hb were measured by means of a near infrared spectroscopy ... improvement in motor control and reaching tasks, and increased his AAT (Aachener Aphasie Test) score from 52/60 to 56/60 Measurement protocol We applied TCD and NIRS during baseline conditions and during...
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Báo cáo hóa học:

Báo cáo hóa học: " Excitonic Transitions and Off-resonant Optical Limiting in CdS Quantum Dots Stabilized in a Synthetic Glue Matrix" pptx

... other hand, off resonant nonlinearity has ultrafast response Semiconductor nanocrystals with large nonlinearity are also known to be attractive candidate materials for optical limiting Optical limiters ... induced damage We have synthesized a nanocomposite material incorporating strongly confined CdS nanocrystals of average size 3.4 nm stabilized in a synthetic glue matrix The samples are free standing ... polymer-embedded nanomaterials appear to be better candidate materials for the study of nonlinear optical response Nonlinear refraction has been studied in CdS nanocrystals incorporated in polydiacetylene...
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Báo cáo y học:

Báo cáo y học: " Interferon-γ inhibits interleukin-1β-induced matrix metalloproteinase production by synovial fibroblasts and protects articular cartilage in early arthritis" doc

... al., Interferon-? inhibits interleukin-1?-induced matrix metalloproteinase production by synovial fibroblasts and protects articular cartilage in early arthritis Arthritis Research & Therapy 2010, ... points (Day and Day 3) We observed moderate IL-1β expression in joints affected by AIA on Day Abundant staining was detected in the synovial lining layer, joint exudate and focal areas of synovial ... green staining despite the discernible inflammatory synovial environment (Figure 4EH) IFN-γ protects the joint against early articular cartilage damage in AIA By Day all parameters of early arthritis...
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Structure property relationship of crystalline poly(lactic acid)s DFT DFPT studies and applications

Structure property relationship of crystalline poly(lactic acid)s DFT DFPT studies and applications

... STRUCTURE- PROPERTY RELATIONSHIP OF CRYSTALLINE POLY(LACTIC ACID)S: DFT/ DFPT STUDIES AND APPLICATIONS LIN TINGTING (M Sc., National University of Singapore) (B Sc and M Sc., Xiamen ... chain primary structures, conformations and packings; crystal structures and the degree of crystallinity etc Hence, an understanding on the relationship of structure/ morphology and property is ... chain primary structures, conformations and packings (the crystal structures and the degree of crystallinity) Therefore a study on the relationship of structure, morphology, and property is fundamentally...
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Doxorubicin conjugated to d alpha tocopheryl polyethylene glycol 1000 succinate (TPGS) in vitro cytotoxicity, in vivo pharmacokinetics and biodistribution

Doxorubicin conjugated to d alpha tocopheryl polyethylene glycol 1000 succinate (TPGS) in vitro cytotoxicity, in vivo pharmacokinetics and biodistribution

... Cyclosporine A DCC N,N'-dicyclohexylcarbodiimide DCM Dichloromethane DMAP Dimethylaminopyridine DMEM Dulbecco’s modified eagle medium DMSO Dimethyl sulfoxide DOX Doxorubicin FBS Fetal bovine serum ... various drug concentrations At last, in chapter 5, pharmacokinetics and biodistribution via intravenous administration of the TPGS-DOX and free DOX are included, followed by final conclusions and some ... synthesized by random ring-opening co-polymerization of glycolic acid and lactic acid, producing different forms depending on the ratio of two monomers PLGA can be degraded by hydrolysis in water Besides,...
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Formulation of superparamagnetic iron oxides by nanoparticles of biodegradable polymer for magnetic resonance imaging (MRI)

Formulation of superparamagnetic iron oxides by nanoparticles of biodegradable polymer for magnetic resonance imaging (MRI)

... some suggestions for future directions of this research are given Chapter Literature Review 2.1 Nanoparticles of Biodegradable Polymers 2.1.1 Basic information of Biodegradable Polymers Recently, ... of iron loading (% w/w) was calculated as the ratio of the mass of iron (mg) that can be detected using ICP analysis to the sum of the mass of iron (mg) and the mass of polymer (mg) 3.3.7 Magnetic ... are termed superparamagnetic iron oxides (SPIOs) where nanoparticles have a size greater than 50 nm (coating included) and the second type termed ultrasmall superparamagnetic iron oxides (USPIOs)...
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Multimodal tumor imaging by iron oxides and quantum dots formulated in poly (lactic acid) d alpha tocopheryl polyethylene glycol 1000 succinate nanoparticles

Multimodal tumor imaging by iron oxides and quantum dots formulated in poly (lactic acid) d alpha tocopheryl polyethylene glycol 1000 succinate nanoparticles

... MULTIMODAL TUMOR IMAGING BY IRON OXIDES AND QUANTUM DOTS FORMULATED IN POLY (LACTIC ACID)- DALPHA -TOCOPHERYL POLYETHYLENE GLYCOL 1000 SUCCINATE NANOPARTICLES TAN YANG FEI ... buffered saline Poly Dispersity Index Polyethylene glycol Positron emission tomography Poly (lactic acid) Poly (lactic acid)- D- alpha- tocopheryl polyethylene glycol 1000 succinate Poly (lactic acid) -poly ... 27 In addition to proteins, biodegradable polymers such as poly (lactic acid) (PLA) and poly( lactic-co-glycolic acid) (PLGA) and various biodegradable copolymers such as poly( lactic acid)- poly...
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Targeted delivery of doxorubicin conjugated to folic acid and vitamin e d a tocopheryl polyethylene glycol succinate (TPGS

Targeted delivery of doxorubicin conjugated to folic acid and vitamin e d a tocopheryl polyethylene glycol succinate (TPGS

... care and understanding all time during my candidature I am grateful to my senior, Cao Na, for her extended help and advice and who has imparted her knowledge and expertise in the experimental ... and Low 2002) Folate targeted drug delivery has emerged as an alternative therapy for the treatment and imaging of many cancers and inflammatory diseases It was said that the administration of ... well as cancers of the lung, breast, and ovary Because these drugs damage DNA, they can cause long-term damage to the bone marrow In a few rare cases, this can eventually lead to acute leukemia...
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