... previous findings showing mRNA of PAR1 is expressed in primary breast cancer tissue; mediates the invasive potential of certain breast cancer cell lines [13,15], and that it is involved in the tumour ... contribTable 2: Distribution of demographic, clinical, and pathological variables of breast cancer patients as a function of PAR1 expression Variable PAR1* (+) PAR1* (-) Age (years) Age at menarche ... infiltrating ductal carcinoma, whereas very low amounts are found in normal and premalignant atypical intraductal hyperplasia [13-16] Despite these advances, the role of PAR1 in breast cancer cell invasion...