Investigations on the antimalarial activity of alkoxylated and hydroxylated chalcones 1
Investigations on the antimalarial activity of alkoxylated and hydroxylated chalcones 1
... 2,4-dichloro H Compound No c 19 22 23 31a 32a 38 11 1 11 2a 11 3 11 4 11 5 11 6 11 7 13 5 25 26 33a 34a 39 12 1 12 2 12 3 12 4 12 5 12 6 12 7 13 6 2 01 202a 203 204 205a 206 207a 208a 209a 210 a 211 2 31 232 233a 234 235 ... No c 11 12 13 27a 28a 35 36 40 12 8 12 9 13 0 13 1 13 2 13 3 13 4 29a 30a 10 1 10 2 10 3 10 4 10 5 10 6 10 7 10 8 10 9 11 0a 212 a 213 a 214 a 215 a 216 a 217 218 219 220 2 21 222 223 224 225 226 227 228 229 230 R’ 2’,3’,4’-trimethoxy ... Effects on falcipain-2 and associated changes in the food vacuole on incubation 10 3 6.3.3 Binding to heme 10 5 6.4 Discussion 11 0 6.5 Conclusion 11 1 SECTION SEVEN: CONCLUSION 11 3 -11 5 APPENDICES A1-A16...
- 73
- 162
- 0
Investigations on the antimalarial activity of alkoxylated and hydroxylated chalcones 3
... DISUBSTITUTION d 11 12 13 27 28 35 36 40 128 129 130 131 132 133 134 3. 3776 3. 3466 3. 9 830 3. 10 73 3. 430 1 3. 84 93 3. 030 0 3. 0749 3. 0168 3. 47 13 3.2579 3. 8691 4.0709 3. 4016 4.1201 3. 9210 3. 17 13 3.4658 3. 85 ... 8.54 0 .37 8 0 .38 1 0 .38 4 0 .38 5 0 .38 0 0 .37 6 0 .38 2 0 .38 1 0 .36 9 0 .38 9 0 .38 3 0 .38 5 0 .38 5 0 .37 8 0 .38 1 0 .38 7 0 .38 6 0 .39 0 0 .39 5 0 .38 8 0 .37 5 0 .38 3 0 .38 7 0 .38 3 0 .38 2 0 .38 7 0 .38 2 0 .38 0 0 .37 7 0 .37 6 2.4 532 2.4176 ... 3. 2 532 3. 2618 3. 6945 4 .36 89 2.4142 3. 8824 3. 7707 3. 833 1 4.75 4.60 4.06 3. 46 3. 18 4.20 3. 06 3. 06 3. 67 3. 09 3. 34 3. 32 3. 89 4.04 4. 03 4.48 2.92 4 .35 2.49 3. 44 3. 07 3. 04 3. 04 3. 30 4.58 4.04 3. 16 3. 65...
- 45
- 234
- 0
Investigations on the antimalarial activity of alkoxylated and hydroxylated chalcones 2
... 55.50 28 .10 33.00 24 .85 100.00 Toxicity to macrophages (µM) c 30 30 30 10 10 30 30 10 10 ND 30 30 ND 10 30 30 10e Compound number 21 7 22 0 22 1 22 2 22 4 22 5 22 6 22 7 22 8 22 9 23 0 23 1 23 2 23 3d 23 4 23 5 23 6 ... 39 121 122 123 124 125 126 127 136 41f 20 1 20 2d 20 3 20 4 20 5d 20 6 20 7d 20 8d 20 9d 21 0d 21 1 24 5 21 2d 21 3d 21 4d 21 5d 21 6d Ring B 4’-ethoxy 4’-butoxy 2 ,4’dihydroxy 4’-hydroxy Ring A 4-fluoro 2, 4-dichloro ... of the compound at pH 7.0 5 .2. 2 .2 Determination of the chemical shift of the carbonyl carbon The method is described in Section 3.3.3 5 .2. 2.3 Determination of physicochemical parameters of chalcones...
- 42
- 196
- 0
Investigations on the antiplasmodial activity of ferrocenyl chalcones
... activity of ferrocenyl chalcones The other physicochemical properties of the ferrocenyl chalcones should be considered together with their oxidant potential In conclusion, the study has shown that ferrocenyl ... Chemical Considerations 3.3.1 Synthesis of ferrocenyl chalcones The syntheses of the two series of ferrocenyl chalcones proceeded by basecatalyzed Claisen-Schmidt condensation, with some modifications.62 ... because of the larger dihedral angle between the protons The coupling constants of the vicinal protons indicated that the ferrocenyl chalcones were obtained in the E configuration When the double bond...
- 179
- 241
- 0
Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx
... IMAGEQUANT software, and depurination was calculated by relating the amounts of the small aniline-fragment and 5.8S rRNA and expressing values as a percentage Reassociation and quantification of ... carried out for each individual atom Data collection and refinement statistics are given in Table Assay of the N-glycosidase activity of ricin A chain variants The activity of each of the RTA ... To assess the effect of substitutions made at each of the arginyl residues on catalytic activity of RTA, the ability of each of the purified RTA variants to depurinate yeast ribosomes was compared...
- 10
- 616
- 0
báo cáo hóa học: " The effect of hip abduction on the EMG activity of vastus medialis obliquus, vastus lateralis longus and vastus lateralis obliquus in healthy subjects" pot
... extension at 90° of flexion, MVIC hip abduction at 0° of abduction, MVIC hip abduction at 30° of abduction) were obtained dividing the highest EMG value of the MVIC trials by the EMG value of a ... Lateral insertion in vastus lateralis muscle (vastus of the obliq(P) and its view of the the thigh -lateral border of the patella Figure Lateral view of the right thigh showing the origin of the obliquus ... 90° of flexion in a seated position; 2) MVIC hip abduction at 0° of abduction, with patients in side-lying position with the knee in full extension; 3) MVIC hip abduction at 30° of abduction, ...
- 8
- 427
- 0
An experimental study on the thermal valorization of municipal and animal wastes
... expresses the effect of ambient gas composition and f describes the change of surface reactivity as a function of the fractional burn off: As the function g(Po2) represented the partial pressure of ... can be found in a previous study [11] Results and discussion 4.1 Characterization of the fuels A comparison of the proximate and ultimate analysis results, as well as of the calorific value of ... fuels, to produce heat and power Rather than being a problem of waste, poultry litter and RDF can and should be a source of energy The results can aid the proper design of boilers and furnaces using...
- 8
- 627
- 0
Tài liệu Báo cáo khoa học: Comparative studies on the functional roles of N- and C-terminal regions of molluskan and vertebrate troponin-I pdf
... 6A,B) In the present study, we compared the functional roles of the N- and C-terminal regions of 4482 H Tanaka et al molluskan and vertebrate TnI and revealed for the first time that (a) the alternative ... of the troponin complex In molluskan muscles, the C-terminal region does not function and troponin regulates contraction only through the activation exerted by the N-terminal region of TnI Experimental ... amount of nonspecific precipitation of the TnI-fragment was also monitored by simultaneous centrifugation of the sample containing no actin-tropomyosin under the same conditions Reconstitution of...
- 12
- 514
- 0
Tài liệu Báo cáo khoa học: Coordination chemistry of iron(III)±porphyrin±antibody complexes In¯uence on the peroxidase activity of the axial coordination of an imidazole on the iron atom ppt
... a monoclonal anti-porphyrin Ig, with an iron( III)-DoCPP cofactor and imidazole as an axial ligand of the iron which, respectively, mimick the heme cofactor and the axial histidine ligand of the ... Binding of imidazoles to the iron( III) of Fe(ToCPP) and Fe(ToCPP))13G10 The second part of our results concerns the binding of imidazole derivatives on the iron of Fe(ToCPP) either alone in solution ... binding of ligands on the iron of Fe(porphyrin))13G10 complexes: (A) binding of H2O2 on the iron of 13G10-(Fe(ToCPP), (B) binding of two CN± ligands on the iron of 13G10-(Fe(ToCPP), (C) binding of...
- 11
- 470
- 0
Research " Essays on the Equilibrium Valuation of IPOs and Bonds " pdf
... Berkeley May 2000 Essays on the Equilibrium Valuation of IPOs and Bonds Copyright May 2000 by Kehong Wen Abstract Essays on the Equilibrium Valuation of IPOs and Bonds by Kehong Wen Doctor of Philosophy ... by the coe¢cients a and b: The magnitude of ´ measures the degree of erosion of old knowledge Remark This assumption and the assumption about the IPO payo¤ (aM + N) recognize the crucial role of ... under the environment of changing participation restrictions can be analyzed I obtain closed-form solution for the dynamic rational-expectations equilibrium The equilibrium concept used is the...
- 152
- 365
- 0
Báo cáo khoa học: Investigations on the evolutionary conservation of PCSK9 reveal a functionally important protrusion pot
... vertebrates In conclusion, there is a single, large, evolutionarily conserved protrusion on the surface of the catalytic domain of PCSK9 The lack of other residue conservation on the PCSK9 surface ... of the mutants S15 3A -PCSK9, Q19 0A -PCSK9, R19 4A -PCSK9, D20 4A -PCSK9, K22 2A -PCSK9, R23 7A -PCSK9, D23 8A -PCSK9, D37 4A -PCSK9, C37 5A -PCSK9, S37 6A -PCSK9, T37 7A -PCSK9, C37 8A -PCSK9 and F37 9A -PCSK9 was determined ... using an antibody against the prodomain of PCSK9 The prodomains of R19 4A -PCSK9 and D20 4A -PCSK9 migrated normally (Fig 6) Thus, the two mutants were autocatalytically cleaved in a normal fashion...
- 13
- 378
- 0
Báo cáo khoa học: "Daily enteral feeding practice on the ICU: attainment of goals and interfering factors" ppsx
... influences of a skewed duration of feeding Success of enteral nutrition During the build-up phase of feeding, the number of successful feeding days increased from 39% (124 of 316) on day to 51% (112 of ... adverse effect on the success of feeding (Table 4) Discussion With the use of a meticulous, daily record of the ICU feeding practice we evaluated the feasibility of prescribed enteral feeding for ... respiration and tracheostomy, only mechanical ventilation was included in the analysis A comparison of the results of the univariate analysis between the complete data set and a subset of the first...
- 8
- 253
- 0
An investigation on the root system of mangroves and its influence on current flow
... AN INVESTIGATION ON THE ROOT SYSTEM OF MANGROVES AND ITS INFLUENCE ON CURRENT FLOW ZHANG XIAOFENG (B.Eng, Hohai University, China) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... one foot on land and one in the water These botanical amphibians occupy a zone in the intertidal areas of rivers, estuaries, deltas and lagoons in tropical regions, yet the forests mangroves ... mangrove trees to reduce the strength of tsunamis Their mangrove model consisted of three parts: root, trunk and leaf system The root and leaf systems were made of permeable porous sheet and the...
- 256
- 636
- 0
The Materials Science of Coatings and Substrates Part 1 ppt
... Plating Recominendations of ASTM (a) Tensile Strength MPa 1m -11 00 11 01- 1200 12 01- 1300 13 01- 1400 14 01- 1500 15 01- 1 600 16 01- 1700 17 01- 1800 Temp psi 14 5,OOO -16 0,ooO 16 0,00 017 4,000 17 4,OOO-l89,oOO 89,OOO-203,OOO ... Vol XV, No 8, 18 (Aug 19 90) P H Abelson, "Support for Materials Science and Engineering", Science, 247, 12 73 (16 March 19 90) A L Bement, Jr., "The Greening of Materials Science and Engineering", ... 203,OOO- 218 ,ooO 218 ,000-232,000 232,000-247,000 247,000-2 61 ,OOO a From reference 14 O C 19 0-220 19 0-220 19 0-220 19 0-220 19 0-220 19 0-220 19 0-220 19 0-220 Time Hours Minimum Minimum 10 Minimum 12 Minimum...
- 25
- 461
- 0
Từ khóa: 4 effects of pressure and temperature on the antioxidant activity of lycopeneon the computational complexity of clustering and related problemsthe effect of attention and news on the buying behavior of individual and institutional investorsradicals on the kinetic characteristics of quercetin and dihydroquercetin in the methyl oleate oxidationanalysis on the technical progress of steelmaking and refininghuntley et al on the morphological history of proterozoic and cambrian acritarchshistorical perspective on the physiological role of ls and the causes of rdson the prenatal development of function and structure in the somesthetic cortex of the sheepout on the water lessons of place and timenew concepts on the critical functions of cancer and metastasis initiating cells in treatment resistance and disease relapse molecular mechanisms signaling transduction elements and novel targeting therapieseffect of pk on the proteolytic susceptibility of soluble and insoluble prpstate on the natural means of selection and on the comparison of domestic races and true species2013 quot a comparative study on the antioxidant activity of methanolic extracts from different parts of morus alba l moraceae quot bmc res notes 6 24 pp 1 9new results on the political economy of redistribution and inequalityranking of all pad designs based on the initial rate of hybridization and maximum raw intensity attained rank 1 denotes the best performanceBáo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Nghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Thơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘITÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ