Cultivated conjunctival epithelial transplantation for the treatment of ocular surface disease

... crucial for enhancing grafttake and regeneration of the conjunctival surface following clinical transplantation I report the successful use of these cultivated conjunctival epithelial equivalents for ... subpopulation of epithelial cells of the ocular surface The limbus is a 1.5 to 2mm wide area that straddles the cornea and bulbar conjunctiva Corneal epithelial stem cells reside in the basal region of the ... complicated by the multitude of epithelial and mesenchymal factors that contribute to the complex ocular environment Therefore cell culture is one of the best means for examination of the role of individual...

Báo cáo khoa học: The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer’s disease pptx

... Modulation of metal availability for treating AD P J Crouch et al research attention as potential therapeutic targets Plaques and NFTs, however, cannot be regarded as ‘upstream’ causative factors ... hyperphosphorylation occurs because of an imbalance in the activity of tau kinases and phosphatases [3] One particular tau kinase pertinent to metal dyshomeostasis in AD is glycogen synthase kinase-3 ... Oxidative damage to mitochondrial DNA is increased in Alzheimer’s disease Ann Neurol 36, 747–751 Modulation of metal availability for treating AD 81 Maynard CJ, Cappai R, Volitakis I, Cherny RA,...

Transplantation of mesenchymal stem cells for the treatment of parkinsons disease in a mouse model

... TRANSPLANTATION OF MESENCHYMAL STEM CELLS FOR THE TREATMENT OF PARKINSON’S DISEASE IN A MOUSE MODEL CHAO YIN XIA MD A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF ANATOMY ... MPTP, an acute insult initiates an inflammatory reaction that becomes self sustaining after the initiating agent has disappeared The MPTP model of PD has been invaluable in the studying of the ... cell transplantation attenuates blood brain barrier damage and neuroinflammation and protects dopaminergic neurons against MPTP toxicity in the substantia nigra in a model of Parkinson’s disease...

Báo cáo y học: "Endoscopic Facet Debridement for the treatment of facet arthritic pain – a novel new technique

... low back pain Pain Physician 1999;2:59-64 Manchikanti L, Pampati V, Fellows B, et al The diagnostic validity and therapeutic value of lumbar facet joint nerve blocks with or without adjuvant agents ... men; mean age 64, range 22-89) were included Length of follow-up was at least years with a maximum of years Location of facet pain was cervical in 45, thoracic in 15, and lumbar in 114 patients ... endoscopic facet debridement comparable to the more commonly used RFA, with results durable for at least years Larger scale trials with a control group are warranted to further evaluate the relative...

Báo cáo y học: "Endoscopic thoracic laminoforaminoplasty for the treatment of thoracic radiculopathy: report of 12 case"

... endoscopic laminoforaminoplasty, should decrease the risk of major adverse events, allow for same day hospital discharge, and decrease the need for postoperative analgesia and immobility [5] [6] In the ... study, no adverse events occurred and all patients were discharged the day of surgery Additionally, there was no need for thoracotomy, unlike other surgical approaches At the same time, reports ... Conclusions Thoracic radiculopathy is rare, as evidenced by the paucity of literature regarding the appropriate management of these patients In our experience, patients with thoracic central and foraminal...

Behavior of Nitrite Oxidizers in the Nitrification/Denitrification Process for the Treatment of Simulated Coke-Oven Wastewater

... -80oC The extraction of DNA was performed with Fast DNA SPIN Kit for Soil (Qbuiogene, USA) according to the instruction by the manufacturer In the preliminary step to nawwor down the species of ... affected the activities of nitrite oxidizing bacteria - 31 - Journal of Water and Environment Technology, Vol.5, No.1, 2007 Figure Behavior of nitrate and nitrite at the end of the aerobic tank Behavior ... quantitative In order to more accurately determine the behavior of nitrifiers, a quantitqative PCR method (Quanching Primer-PCR) for the determination of Nitrobacter species was developed by using the...

Contact-Adsorption-Regeneration-Stabilization Process for the Treatment of Municipal Wastewater

... results of the CARS process for the municipal wastewater treatment The technical feasibility of this process was demonstrated, and the process optimization was performed In addition, the adsorption ... an inflow of 10 L/h Domestic wastewater was collected with a central sewerage network for the preparation of the influent wastewater The composition of the influent was given in Table The average ... in the PO43 P removal These results revealed that the selection of the operational parameters of the CARS process had a great influence on the overall system performance Adsorptive capability of...

Tài liệu Bevacizumab and cetuximab for the treatment of metastatic colorectal cancer docx

... considered evidence on the nature of the condition and the value placed on the benefits of bevacizumab and cetuximab by people with metastatic colorectal cancer, those who represent them, and clinical ... from data in the RCT The survival of patients receiving ASC/BSC was calculated from the survival of the patients in the cetuximab monotherapy arm of the RCT The data from the monotherapy arm NICE ... 4.3 Consideration of the evidence 4.3.1 The Committee reviewed the data available on the clinical and cost effectiveness of bevacizumab and cetuximab for metastatic colorectal cancer, having considered...

Báo cáo khoa học: A guide to taming a toxin – recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer ppt

... B, Nakamura M, Hwang J, Kreitman RJ et al (2006) Characterization of the B cell epitopes associated with a truncated form of Pseudomonas exotoxin (PE38) used to make immunotoxins for the treatment ... Functional analysis of domains II, Ib, and III of Pseudomonas exotoxin J Biol Chem 264, 1425 6– 14261 Kihara A & Pastan I (1994) Analysis of sequences required for the cytotoxic action of a chimeric toxin ... Bruland OS & Pastan I (2001) Cytotoxicity of antiosteosarcoma recombinant immunotoxins composed of TP-3 Fv fragments and a truncated Pseudomonas exotoxin A J Immunother 24, 14 4–1 50 Onda M, Bruland...

Pelvic floor muscle training and adjunctive therapies for the treatment of stress urinary incontinence in women: a systematic review doc

... in the last decade (1995–2005) Background and rationale The International Continence Society defines urinary incontinence (UI) as the complaint of any involuntary leakage of urine [1] It is a ... duration of the training programs and compliance) [10] The effect of specifically activating or de-activating the abdominal wall during PFMT was investigated While reducing abdominal muscle activity ... as pelvic floor muscle training with, and without, adjunctive physical therapies such as biofeedback, electrical stimulation or vaginal weights for the treatment of SUI in women The review addressed...

Best Practice Policy Statement on Cryosurgery for the Treatment of Localized Prostate Cancer pptx

... Practice Statement on Cryosurgery for the Treatment of Localized Prostate Cancer The supporting systematic literature review and the drafting of this document were conducted by the Cryosurgery for Treatment ... a Best Practice Statement (BPS) addressing the use of cryosurgery for the treatment of localized prostate cancer A BPS uses published data in concert with expert opinion, but does not employ formal ... and the role of cryosurgery in this setting is currently undetermined Patient Selection Cryosurgery of the prostate is a locally ablative treatment option for the management of prostate cancer...

SYNTHESIZE AND INVESTIGATE THE CATALYTIC ACTIVITY OF THREE-WAY CATALYSTS BASED ON MIXED METAL OXIDES FOR THE TREATMENT OF EXHAUST GASES FROM INTERNAL COMBUSTION ENGINE

... The Tien Synthesize and investigate the catalytic activity of three-way catalysts based on mixed metal oxides for the treatment of exhaust gases from internal combustion engine CONTENT OF THESIS ... Nguyen The Tien 18 Synthesize and investigate the catalytic activity of three-way catalysts based on mixed metal oxides for the treatment of exhaust gases from internal combustion engine of three-way ... Nguyen The Tien Synthesize and investigate the catalytic activity of three-way catalysts based on mixed metal oxides for the treatment of exhaust gases from internal combustion engine LIST OF TABLES...

báo cáo hóa học:" Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer" pdf

... murine model of ovarian cancer We next tested the impact of anti-CD52 antibody therapy on ovarian tumor growth in vivo using the ID8-VEGF murine ovarian flank tumor model As above, animals with ... treated animals (Figure 6D) These results confirm the anti-tumor activity of anti-VLC therapy, as observed by others, and further support the use of anti-CD52 therapy in humans Discussion Our study ... supporting the use of Alemtuzumab as a therapeutic agent for ovarian cancer patients Materials and methods Tissues Stage III epithelial ovarian cancer (n = 10), and ductal breast cancer specimens...

báo cáo hóa học:" Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors" docx

... individual brain tumor cells [70-72] Novel strategy to improve the effectiveness of systemic chemotherapy The novel strategy that I propose here to improve the effectiveness of systemic chemotherapy ... across the BBTB [44-46], and the temporary opening of the junctions between endothelial cells of the BBTB to enhance the permeation of drugs across the BBTB[34,47,48] The overall ineffectiveness of ... employed in the effort to improve the effectiveness of small molecule systemic chemotherapy in treating malignant brain tumors, although neither strategy has been particularly effective The first...

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