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Using computational approach in understanding gene regulatory networks for antimicrobial peptide coding genes

Using computational approach in understanding gene regulatory networks for antimicrobial peptide coding genes

Using computational approach in understanding gene regulatory networks for antimicrobial peptide coding genes

... promoter data for (Chapter 7) a) detection of new co-regulated genes, and b) deciphering parts of gene networks of which AMP genes are members 1.4 Contribution of this thesis AMP -coding genes and ... region analysis to find new AMP genes and co-regulated genes is a first of its kind approach in the field of antimicrobial peptides The results of this analysis can guide the way for experimental ... these groups of genes, gene discovery efforts have been undertaken by many groups For example, efforts were directed to the computational discovery of beta defensin producing genes (Scheetz et...
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Dissecting gene regulatory networks in vertebrate development using genomic and proteomic approaches

Dissecting gene regulatory networks in vertebrate development using genomic and proteomic approaches

... also involves studying gene interactions at the transcriptional regulatory level and at protein interaction level GRNs for certain lineage specification have been mapped in detail in invertebrate ... urchin and in certain in vitro model systems for vertebrates Studying GRNs in vertebrate development poses various challenges, arising from the complexity of the genome and the body plans of vertebrates ... the development of novel approaches to study GRNs in development Developments in transgenic methods, genomic and proteomic technologies have opened new vistas for exploring gene regulatory networks...
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Báo cáo y học:

Báo cáo y học: "Construction of Gene Regulatory Networks using biclustering and Bayesian networks" docx

... Construction of Gene Regulatory Networks using biclustering and Bayesian networks Fadhl M Alakwaa1*§, Nahed H Solouma and Yasser M Kadah3* University of Science and Technology, Sana'a, Yemen Department of ... supported by a grant from the University of Science & Technology, Yemen The authors would like to thank Prof Dana Pe'er, Columbia University; Dr Kevien Yip, Yale University and Prof G Stolovitzky, IBM ... Figure ROC and PR curves of different biclustering networks that have learned using Bayesian networks [29] A performance comparison of networks generated from learning corresponding biclustering...
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Báo cáo hóa học:

Báo cáo hóa học: " Probabilistic polynomial dynamical systems for reverse engineering of gene regulatory networks" docx

... introduce a stochastic generalization of polynomial dynamical systems, namely, probabilistic polynomial dynamical systems, which is also a generalization of the above-mentioned probabilistic Boolean ... models In the next section, we present our method for the reverse engineering of gene regulatory networks as probabilistic polynomial dynamical systems Then we demonstrate this method using the ... provide a systematic method for the reverse engineering of gene regulatory networks as probabilistic Boolean nested canalyzing networks Appendices Polynomial dynamical systems Definition 1.1 Let...
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Báo cáo hóa học:

Báo cáo hóa học: " Research Article A Cross-Layer Approach in Sensing and Resource Allocation for Multimedia Transmission over Cognitive UWB Networks" docx

... the sensing and data transmission in accordance with the PRR based time slot allocation, while the PHY layer performs adaptive modulation and coding to allow data transmission rate adaptation At ... action can be taken Sensing information can be a consideration for QoS requirements especially in multimedia application as it can assist C -UWB to dynamically allocate appropriate resources in ... MAC Dynamics of queue due to packet arrival Queue status and time slot allocation PRR based resource allocation and packet scheduling SNR and sensing time Adaptive modulation and channel coding...
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Báo cáo hóa học:

Báo cáo hóa học: " Research Article Inference of Gene Regulatory Networks Based on a Universal Minimum Description Length" pot

... Inference, Morgan Kaufmann, San Francisco, Calif, USA, 1988 [2] N Friedman, M Linial, I Nachman, and D Pe’er, “Using Bayesian networks to analyze expression data,” Journal of Computational Biology, ... O Yli-Harja, and J Astola, Inference of genetic regulatory networks via best-fit extensions,” in Computational and Statistical Approaches to Genomics, pp 197–210, chapter 11, Kluwer Academic ... 147–167, 2003 [15] A A Margolin, I Nemenman, K Basso, et al., “ARACNE: An algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context,” BMC Bioinformatics, vol 7,...
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Báo cáo hóa học:

Báo cáo hóa học: " Research Article Reverse Engineering of Gene Regulatory Networks: A Comparative Study" ppt

... Island of Hawaii, Hawaii, USA, January 1999 [6] K Basso, A A Margolin, G Stolovitzky, U Klein, R DallaFavera, and A Califano, Reverse engineering of regulatory networks in human B cells,” Nature ... Unfortunately, there are not enough gold standard networks and appropriate experimental data available for a large comparative study For such a study one needs a sufficiently large amount of data of different ... simulated data and presented a framework for testing microarray data analysis tools An artificial data generator has to be independent of the reverse engineering algorithms to avoid a bias in the test...
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Báo cáo hóa học:

Báo cáo hóa học: " Research Article Uncovering Gene Regulatory Networks from Time-Series Microarray Data with Variational Bayesian Structural Expectation Maximization" doc

... dynamic Bayesian networks formulation, our work has two objectives First, given a set of time-series data from a single experiment, we aim at uncovering the underlying gene regulatory networks ... inferring genetic regulatory interactions from microarray experiments with dynamic Bayesian networks, ” Bioinformatics, vol 19, no 17, pp 2271–2282, 2003 [23] K P Murphy, Dynamic Bayesian networks: ... e Bayesian networks, ” Bioinformatics, vol 19, supplement 2, pp ii138–ii148, 2003 [18] S Y Kim, S Imoto, and S Miyano, “Inferring gene networks from time series microarray data using dynamic Bayesian...
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Báo cáo hóa học:

Báo cáo hóa học: " Research Article Comparison of Gene Regulatory Networks via Steady-State Trajectories" pdf

... concentrations of mRNA and proteins induced by gene i, respectively, ci (t) is the fraction of DNA fragments committed to transcription of gene i, κi is the transcription rate of gene i, and τ ... transcriptional regulatory system (tRS) We generate networks using this model and a fixed set θ of parameters We call these networks reference networks A reference network is identified by its set θ of parameters, ... straightforward simulation consists of the design of a reference network, the design of a projected network (for some value of Δx ), the generation of several trajectories for both networks from randomly...
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báo cáo khoa học:

báo cáo khoa học: " Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines" pps

... Prediction of mammalian microRNA targets Cell 2003, 115:787-798 doi:10.1186/gm144 Cite this article as: Sarachana T, et al.: Investigation of post-transcriptional gene regulatory networks associated with ... post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines Genome Medicine 2010, 2:23 ... levels of target genes that, in turn, may be associated with the underlying pathophysiology of ASD, and to provide a better understanding of the role of miRNAs as a post-transcriptional gene regulatory...
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Báo cáo khoa học:

Báo cáo khoa học: "Using Language Resources in an Intelligent Tutoring System for French" pptx

... Issue Introduction, JAI-ED, 5/4, pp 417-428 Hamburger, H.& Hashim, R.(1992) Foreign Language Tutoring and Learning Environment, In " Intelligent Tutoring Systems for Foreign Language Learning, ... System, Proc Language Teaching and Language Technology, Univ of Groningen Swartz, M.L & Yazdani, M (eds.) (19992) Intelligent Tutoring Systems for Foreign Language Learning: The Bridge to International ... Collins: Student Modeling in Intelligent Computer Assisted Language Learning, Instructional Science, 23, pp.65-87 Burton, R R & Brown, J.S (1976) A tutoring and student modeling paradigm for gaming...
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Identification and characterization of CIS regulatory elements for vertebrate developmental control genes

Identification and characterization of CIS regulatory elements for vertebrate developmental control genes

... locate and validate candidate cis- regulatory elements for developmental control genes that are ancient in origin and conserved in evolution 1.1 Cis- Regulatory Elements Cis- regulatory elements ... methods to locate and validate cis- regulatory elements 17 1.5 Genomics era methods to locate and validate cis- regulatory elements ……20 1.6 In silico predictions of cis- regulatory elements ……………………………23 ... [7] and separates genes with discordant expression patterns [8] Locus control regions are made up of multiple cis- regulatory elements and are capable of directing expression of one or more genes...
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Studying Aesthetics in Photographic Images Using a Computational Approach pot

Studying Aesthetics in Photographic Images Using a Computational Approach pot

... aesthetics and originality ratings for a given image A plot of 3581 unique photograph ratings can be seen in Fig As can be seen, aesthetics and originality ratings have approximately linear correlation ... Approach A classic treatise on psychological theories for understanding human perception can be found in [2] Here, we take the first step in using a computational approach to understand what aspects ... between various visual properties of photographic images and their aesthetics ratings We have shown, through using a community-based database and ratings, that certain visual properties tend to...
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Báo cáo sinh học:

Báo cáo sinh học: "Refining transcriptional regulatory networks using network evolutionary models and gene historie" docx

... Zhang and Moret: Refining transcriptional regulatory networks using network evolutionary models and gene histories Algorithms for Molecular Biology 2010 5:1 Publish with Bio Med Central and every ... ancestral networks once we have the genes of these networks We this using a revised version of FastML Refine the leaf networks with new versions of RefineFast and RefineML Repeat steps and as needed ... correlation between generation and reconstruction of networks, we use the leaf networks to create simulated expression data and use our preferred network inference method to reconstruct networks from...
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Using PIX Firewall in SOHO Networks

Using PIX Firewall in SOHO Networks

... on a single outside interface Cisco PIX Firewall and VPN Configuration Guide 5-6 78-13943-01 Chapter Using PIX Firewall in SOHO Networks Using the PIX Firewall DCHP Server Using the PIX Firewall ... Chapter Using PIX Firewall in SOHO Networks Using the PIX Firewall PPPoE Client Enabling PPPoE on the PIX Firewall Note You must complete the configuration using the vpdn command, described in “Configuring ... to the inside (higher security) interface of the PIX Firewall Cisco PIX Firewall and VPN Configuration Guide 5-2 78-13943-01 Chapter Using PIX Firewall in SOHO Networks Using the PIX Firewall...
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