... Given the differences in chromatin conformation and transcriptional activity of GC- and AT-rich chromatin domains, we hypothesized that these domains may also display differences in histone modification ... that out of 11 modifications (histone H4 Lys8 (H4K8) and Lys12 (H4K12), and histone H3 Lys9 (H3K9) and Lys18 (H3K18)) are enriched in GC-rich chromatin and depleted in AT-rich chromatin The levels ... AT-rich chromatin in rpd3Δ cells; rpd3Δ-GC, GC-rich chromatin in rpd3Δ cells; WT-AT, AT-rich chromatin in wild-type cells; WT-GC, GC-rich chromatin in wild-type cells obtain a good fit, implying...