... Marginal Zone B cells 11 1. 4 Humoral Immunity in Atherosclerosis 12 1. 4 .1 Localization of < /b> B cells in Atherosclerosis 12 1. 4.2 Association of < /b> oxLDL-specific antibodies with Atherosclerosis ... further delineates the < /b> B1 population into B1 a (CD5+) and B1 b (CD5-) sub-populations B1 cell populations, unlike B2 cells, are not maintained thro...
... plasma cells in the < /b> bone marrow of < /b> apoE-/- mice Because we maintained the < /b> mice on BrdU in drinking water for one month, the < /b> result is also indicative that these plasma cells accumulated in the < /b> bone ... and/or increased bioavailability of < /b> 7α, 25 -OHC 3.4.1 Increased ch25h mRNA expression in the < /b> spleen of < /b> apoE-/- mice We exami...
... observed in the < /b> spleen of < /b> apoE-/- mice may be due to the < /b> inability of < /b> B cells to fall into the < /b> state of < /b> anergy However, it remains to be determined if APOE protein is crucial in maintaining the < /b> ... observed an increased frequency of < /b> oxLDL-specific oxLDL ASCs in the < /b> bone marrow in apoE-/- mice, indicative of < /b> thei...
... detected in this study The most notable findings were increased < /b> percentage < /b> with < /b> an absolute numbers of < /b> NK and < /b> B cells while reduced percentage < /b> with < /b> an absolute numbers of < /b> CD4 + lymphocytes in the peripheral ... the comparison of < /b> the absolute number < /b> of < /b> various peripheral blood lymphocyte subsets...
... reduced peripheral < /b> blood < /b> pre-switch IgD+CD27+ memory < /b> B cell population The frequencies of B cell subsets defined by the expression of IgD and CD27 in < /b> the peripheral < /b> blood < /b> of patients with longstanding ... synovium, they are also generated in < /b> increased numbers in < /b> patients with RA [19] As a result, post-switch me...
... rituximab therapy < /b> preceded by a decrease in CD19+CD27+ memory B cells in peripheral blood and bone marrow of RA patients We next examined the effect of rituximab therapy < /b> on memory (CD19+CD27+) B cells, ... CD19+CD27+ memory B cells Clinical response to rituximab correlates with depletion of CD19+CD27+ memory B cells in pe...
... Chapter Introduction 22 determines their effector functions The < /b> influence of < /b> cytokines in the < /b> differentiation of < /b> CD4+ T cell subsets and the < /b> effect of < /b> CD4+ T cell subsets with the < /b> emphasis on Tr1 ... When they encounter antigen, T cells are induced to proliferate and differentiate into cells capable of < /b> contributing to th...
... of glycogen in the intact liver in vivo Second, during infusion of [1-1 3C ]glucose, label incorporation was observed not only into the C1 of glycogen but also the C6 , which can only occur by label ... a mechanism can lead to increases in labeling of glycogen C6 even in the presence of decreased activity of the indirect pathway, provided that the increas...
... Rhee SG (20 01) Inactivation of human FEBS Journal 27 5 (20 08) 29 42 29 55 ª 20 08 The Authors Journal compilation ª 20 08 FEBS 29 53 Cysteinyl-based modification of the 20 S proteasome 10 11 12 13 14 15 ... investigating whether that common feature is related to their easy entry into the latent 20 S particle Cysteinyl-based modification of the 20 S proteasome...
... article as: Hughes-Fulford and Li: The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization Journal of Orthopaedic Surgery and Research 2011 6:8 Submit ... Figure FGF-2 and BMP-2, the yin and yang of mineralization: Contrast of effect of 24 hours of treatment with FGF-2 or BMP2 on fold increase in...
... article as: Hughes-Fulford and Li: The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization Journal of Orthopaedic Surgery and Research 2011 6:8 Submit ... Figure FGF-2 and BMP-2, the yin and yang of mineralization: Contrast of effect of 24 hours of treatment with FGF-2 or BMP2 on fold increase in...
... bone fracture healing J Bone Miner Res 2002, 17:963-976 Einhorn TA Do inhibitors of cyclooxygenase-2 impair bone healing? J Bone Miner Res 2002, 17:977-978 Zhang X, Schwarz EM, Young DA, Puzas ... activity of a glucocorticoid-regulated inflammatory cyclooxygenase Proc Natl Acad Sci USA 1992, 89:4888-4892 Raskin JB: Gastrointestinal effects of nonsteroidal anti-inflammatory the...
... Leader peptide domain 5'-CAACACUCGCAAUAUU-3'(sense) 3'-GUUGUGAGCGACGUUAUAA-5'(antisense) α3 domain 5'-AGGUCUUAUGGUGCUGUCAUU-3'(sense) 3'-UUUCCAGAAUACCACGACAGU5'(antisense) Transmembrane domain ... Qa-2 domains for 24 hrs, and the expression of Qa-2 was then determined by reverse transcriptase-PCR and FACS analysis Lanes 4, and (α3 domain, transmembrane domain, and cytoplasmic domain, re...
... 28 2. 1 Fish Spawning and Maintenance 28 2. 2 Molecular Biology Techniques 28 2. 2.1 RT-PCR Molecular Cloning 28 2. 2 .2 Polymerase Chain Reaction (PCR) 29 2. 2.3 Agarose Gel Electrophoresis 29 2. 2.4 ... prior finding of possibly interacting proteins of BNIP- 2 led to the formation of research questions: Does the physical interaction of BNIP- 2 with these prote...