Toxicology and pharmacology investigation of 2 phenylaminophenylacetic acid derived NSAIDs implication of chemical structure on biological outcomes

... 23 2. 2.1 Extraction of diclofenac (3) from Voltaren tablets 24 2. 2 .2 Synthesis of compounds 1, and 25 2. 2 .2. 1 Synthesis of 2- iodophenyl-N, N-dimethylacetamide (25 ) 25 2. 2 .2. 2 General ... Statement of purpose 19 Chapter Design and Synthesis of 2- Phenylaminophenylacetic Acid Derived Compounds 22 2. 1 Introduction 22 2. 2 Experimental methods 23 2. 2.1 ... 72 4 .2. 2.1 Cell harvesting and lysis 72 4 .2. 2 .2 SDS-PAGE and Transfer 72 4 .2. 2.3 Detection 73 4 .2. 3 Cell-based COX-1 inhibition assay 73 4 .2. 4 Cell-based COX-2...

Tài liệu Investigating the Role of Poultry in Livelihoods and the Impact of Avian Flu on Livelihoods Outcomes in Africa docx

... 2008; Aning, Turkson, and Asuming-Brempong 2008; Obi, Oparinde, and Maina 2008; Omiti and Okuthe 2008) Therefore, information regarding the role of poultry in the livelihoods of small-scale poultryproducing ... Birol, and D Roy 2010 Investigating the role of poultry in livelihoods and the livelihoods impact of HPAI in Nigeria DFID-funded project for Controlling Avian Flu and Protecting People’s Livelihoods ... No information is available on the costs of culling, diagnostic testing of samples, cleaning and disinfection, and other administrative costs (Obi, Oparinde, and Maina 2008) Regarding the impacts...

The Impact of Social Structure on Economic Outcomes pptx

... “structural holes” in the network 4) The Interpenetration of Economic and Non -Economic Action Much social life revolves around a non -economic focus Therefore, when economic and noneconomic activity ... economic and noneconomic costs of severing a long-time tie and the available social alternatives Thus, the economic ﬂexibility of the system depends on the social structure of the trade relation” (p ... of the situation The theoretical issue is often not one of economic and sociological arguments conﬂicting, but rather of the weakness of both in understanding how actors with simultaneous economic...

Spectroscopic and Microscopic Investigation of Gold NanoparticleFormation: Ligand and Temperature Effects on Rate and Particle Size

... migration of thiolated ligands would lead to less particle organization Correlation of Particle Size and Size Dispersion with Rate of Nucleation and Growth Time We have discussed the nanoparticle ... nucleation and growth processes The temperature eﬀects on particle size and size dispersion also can be interpreted based on the rate of nucleation and growth processes At lower temperatures of 25 and ... formation process dependence on concentration of stabilizing ligand (ODT) present and solution temperature In this section, we discuss the correlation of these reaction parameters with the size and...

Experimental and numerical investigation of heat transferand phase change phenomena during excimer laser interactionwith nickel

... explosive phase change occurs at a laser ~uence of about 4[1 J cm−1[ 2[ Numerical modeling Numerical modeling is carried out to compute the heat transfer and phase change processes during excimer laser ... 2[ Velocity of the plume front and laser energy scattered by the laser! evaporated plume as a function of laser ~uence[ plume\ the percentage of laser energy scattered from the plume and the transmissivity ... of laser energy by the laser! evaporated plume is accounted for by using the measured transient trans! missivity of the excimer laser beam through the laser! evaporated plume[ Results of the numerical...

Báo cáo hóa học: "Investigation of electrical and magnetic properties of ferro-nanofluid on transformers" pptx

... same trend Conclusions In this study, different concentrations of ferro-nanofluids were applied to the magnetic cores of transformers The performance of transformers with magnetic cores of air Figure ... with the MEMS process Authors’ contributions TH performed experimental investigations of electric and magnetic properties of ferro-nanofluids on transformers and prepared the draft, PH proposed ... phases of Fe3O4 nanoparticles Figure The magnetized curve of the Fe O nanofluid measured by a VSM Results and discussion Different magnetic cores, air, and Fe3O4 nanofluids of 0.25, 0.5, 0.75, and...

Regulatory Toxicology and Pharmacology potx

... States for Bt-protected cotton, corn, and potato exceeded 16 million acres in 1998 (Gianessi and Carpenter, 1999), comprising 17 and 18% of the total corn and cotton acreage, respectively (Table ... and kernel rot and producing increased levels of the fumonisin family of mycotoxins Fumonisins are fungal toxins that produce death and morbidity in horses and swine (Norred, 1993) and have been ... Practically nontoxic: fed at 1,700ϫ and 10,000ϫ level in cotton pollen and nectar NOEC Ͼ 200 ppm d Practically nontoxic: fed at 1,700ϫ and 10,000ϫ level in cotton pollen and nectar — Practically nontoxic...

Báo cáo y học: " Explicit and implicit information needs of people with depression: a qualitative investigation of problems reported on an online depression support forum" ppt

... enabling anonymous interaction and mutual support The board was established and hosted by the Depression and Anxiety Consumer Research Unit at The Australian National University It was moderated by academic ... family and community levels, commitment by health professionals and the media, and change to legislation and policy (refer to [35]) Finally, it appears that many people with depression are dealing ... help My family and psychiatrist are as stumped as I am Any clues at all about what I can do? Any suggestions at all would be appreciated” Lack of knowledge about the mental health system may also...

Báo cáo y học: "Non invasive in vivo investigation of hepatobiliary structure and function in STII medaka (Oryzias latipes): methodology and applications" ppsx

... development and application of non invasive in vivo methodologies to the study of biological structure, function and xenobiotic response in STII medaka The development of this in vivo investigatory "system" ... study of piscine biliary transport Collectively these findings demonstrate the ability to study, with high resolution, normalcy and disease/toxicity in vivo in the hepatobiliary system of living ... hepatobiliary architecture Non invasive in vivo imaging in STII medaka allowed the generation of 3D models of the hepatobiliary system (Movies – 9), under conditions of normalcy and toxicity Using LSCM,...

BEYOND THE PALISADE: A GEOPHYSICAL AND ARCHAEOLOGICAL INVESTIGATION OF THE 3RD TERRACE AT ANGEL MOUNDS STATE HISTORIC SITE

... cultural modification of the landscape stops at these walls The mere fact that there are several manifestations of the palisade wall at Angel Mounds (Black 1967; ... research today At Angel Mounds, a large portion of material that was excavated during the era of Works Project Administration (WPA) archaeology in the late ... and a reanalysis of the 3rd Terrace legacy collection from an area that was excavated by Black, the goal was to identify the significance of the 3rd Terrace...

Ab initio and DFT investigation of the mechanism and hydration pattern of sialidase and its inhibitor

... AB INITIO AND DFT INVESTIGATION OF THE MECHANISM AND HYDRATION PATTERN OF SIALIDASE AND ITS INHIBITORS KRISHNAN CHANDRASEKARAN M.S (By Research) Chemistry National University of Singapore A THESIS ... substituents of tamiflu 170-172 Figure 40-44, C6 substituents of tamiflu 174-175 xi SUMMARY This research study addresses the ab initio and DFT investigation of sialidase enzyme mechanism and hydration pattern ... development of sialidase inhibitors Chapter 7, deals with the effect of substituents on the binding affinity of the sialidase inhibitors The substituents were introduced at the C4 and C7 position of DANA...

Experimental and numerical investigation of novel pine oil biofuel in a diesel engine

... Vallinayagam R, Vedharaj S, Yang WM, Raghavan V, Saravanan CG, Lee PS, Chua KJE, Chou SK Investigation of evaporation and engine characteristics of pine oil biofuel fumigated in the inlet manifold ... 131 OPERATION OF PINE OIL IN DUAL FUEL MODE 133 5.1 Investigation of evaporation and engine characteristics of pine oil biofuel fumigated in the inlet manifold of a diesel engine 133 5.1.1 ... kumar Raju, Sankaranarayanan and Karthik Raja for motivating me in all research endeavors and other aspects of my life Last but not least, my fellow confederate and close pal, Dr.Vedharaj Sivasankaralingam...

Numerical and experimental investigation of single and two phase impinging jet heat transfer

... NUMERICAL AND EXPERIMENTAL INVESTIGATION OF SINGLE AND TWO- PHASE IMPINGING JET HEAT TRANSFER ZHENGQUAN LOU (Bachelor, SJTU) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... Micro -Impinging Jet Heat Transfer" , International Journal of Thermal Sciences, Submitted, 2005 Z.Q Lou, C Yap and A.S Mujumdar, "Numerical Investigation of Two- phase Impinging Jet Heat Transfer" , Journal of ... current investigation, the study was mainly focused on the single and twophase impinging jet heat transfer Both numerical and experimental investigations were carried out For the single phase problem,...

The triumph of tagalog and the dominance of the discourse on english language politics in the philippines during the american colonial period 2

... curt and rather humorous description of the language of instruction in the Philippines: The curriculum on the theoretical and academic side is simple in all the courses of study The note of it ... fervor and with a steadfast and sincere belief in the honesty and integrity of their mission.78 The civilizing mission is of course a customary feature of all colonial projects American colonial discourse ... on the U.S Colonial State” in The American Colonial State in the Philippines: Global Perspectives and Michael Adas’ “Improving on the Civilizing Mission? Assumptions of United States Exceptionalism...

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