Investigations on rab31s role in EGFR trafficking and neural progenitor cell differentiation towards astroglia

... pool containing Rab5 and its effector APPL1 (Adaptor protein, phosphotyrosine binding (PTB) 19 Introduction domain, pleckstrin homology (PH) domain, leucine zipper-containing protein 1) is ... 87 The role of Rab31-interacting proteins in Rab31-mediated EGFR trafficking 89 5.1 Chapter Introduction: Potential Rab31-interacting proteins in an EGFRtrafficking complex ... GFAP-positive cells obtained This suggests that Rab31 plays a role in the differentiation of neural progenitor cells of the brain This may be, in part, due to its role in EGFR trafficking Results...

Báo cáo y học: "Expression of CD147 on monocytes/macrophages in rheumatoid arthritis: its potential role in monocyte accumulation and matrix metalloproteinase production" ppt

... those in the cultures of human monocytes or HFC alone (b) Gel zymography detection of MMP-2 and MMP-9 in human CD14+ monocytes of normal control monocytes, in HFC, and in a co-culture of the ... expression on monocytes is possibly associated with the pathogenesis of RA and CD147 may play an important role in the cartilage and bone destruction of RA To confirm the expression of CD147 in synovium ... elucidated Conclusion We conclude in this study that the increased expression of CD147 on monocytes/macrophages in RA may be responsible for elevated MMP secretion, cell invasion and the CyPA-mediated...

Tài liệu LIVESTOCK''''S ROLE IN CLIMATE CHANGE AND AIR POLLUTION ppt

... acidity, integrated pest management, double-cropping, and crop Livestock’s role in climate change and air pollution rotations including green manure and cover crops Increasing crop yields result in ... 2000) Overgrazing is the greatest cause of degradation of grasslands and the overriding humaninfluenced factor in determining their soil carbon Livestock’s role in climate change and air pollution ... the decline of ruminant livestock in relative terms, and the overall trend towards higher productivity in ruminant production, it is unlikely Livestock’s role in climate change and air pollution...

Tài liệu Báo cáo khoa học: Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites doc

... that the hypodermis of the body wall, which synthesizes components of the cuticle, may offer a useful target for studies into the mechanism of the development and molting process in the roundworms ... presence of increasing concentrations of inhibitors for 10 days, and the number of molting larvae was determined Molting was manifested by shedding of the L3 cuticle Results Identiﬁcation of cDNA ... involved in the molting process, we examined the effects of two PPase speciﬁc inhibitors, imidodiphosphate (IDP, 1-0631; Sigma) and NaF on development and molting of A suum lungstage L3 to fourth-stage...

Báo cáo khoa học: Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis doc

... postinfection, we observed a marked difference between the number of CFUs of the wild-type strain and that of the PMM56 mutant strain in lungs and in the spleen (Fig 7A) Indeed, both strains ... cell envelope of M tuberculosis and to virulence [3–6] Nevertheless, their precise molecular mechanisms of action are still unknown, and the speciﬁc roles of the various members of the DIM family, ... DIM A and DIM B, in these functions have never been investigated The recent developments in our understanding of the biosynthetic pathway of DIMs have provided the means to investigate the contribution...

Guidance on Responsible business in conflict-affected and HiGH-Risk aReas: a ResouRce foR companies and investoRs potx

... Guidance on Responsible Business in Conflict-Affected and High-risk Areas: A Resource for Companies and Investors aims to assist companies in implementing responsible business practices in conflict-affected ... international laws and standards for guidance on financial transactions regarding interactions with groups listed on international terrorist lists Take a broad and inclusive approach to providing ... Make reasonable efforts to disclose information that will enhance investors understanding of business activity in a timely manner and taking account of legal and commercial considerations As...

Báo cáo hóa học: " Targeting the inflammation in HCV-associated hepatocellular carcinoma: a role in the prevention and treatment" pptx

... (TIRdomain-containing adapter-inducing interferon-b) joining the RIG-I/MDA5 pathway In the other pathway, TLR7 senses single-strand HCV RNA and via the MyD88 adaptor protein activates IRAK4/IRAK1 These kinases ... increased levels of aspartate transaminase, alanine transaminase, alkaline phosphatase, acid phosphatase, lactate dehydrogenase, gamma-glutamyltransferase, 5’-nucleotidase, bilirubin, alpha-fetoprotein, ... The role of cytokines in hepatocellular carcinoma J Leukoc Biol 2006, 80(6):1197-213 51 Nakagawa H, Maeda S, Yoshida H, Tateishi R, Masuzaki R, Ohki T, Hayakawa Y, Kinoshita H, Yamakado M, Kato...

báo cáo hóa học: " Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Aβ immunotherapy" pot

... of IL -1 signaling on microglial activation, on IL -1- mediated inflammatory responses following Aβ vaccination, and on Aβ deposition during normal aging, we used interleukin -1 receptor 1- knockout ... inflammatory responses following Aβ vaccination and on Aβ deposition during normal aging using interleukin -1 receptor 1- knockout (IL -1 R1-/-) mice [40-42] that were crossed to APP Tg2576 transgenic mice ... transgenic mice J Clin Invest 2005, 11 5(2):428-433 Page 11 of 13 (page number not for citation purposes) Journal of Neuroinflammation 2006, 3 :17 10 11 12 13 14 15 16 17 18 19 20 21 Pfeifer M, Boncristiano...

Báo cáo hóa học: " A review of experimental investigations on thermal phenomena in nanofluids" ppt

... effects of the particle concentration, the material of the particles, and the geometry of the containing cavity on natural convection were investigated A systematic and definite deterioration of natural ... enhancement in metal nanoparticle suspensions Int Commun Heat Mass Transf 2008, 35:867-872 Pantzali MN, Kanaris AG, Antoniadis KD, Mouza AA, Paras SV: Effect of nanofluids on the performance of a miniature ... Thomas and Balakrishna Panicker Sobhan: A review of experimental investigations on thermal phenomena in nanofluids Nanoscale Research Letters 2011 6:377 Submit your manuscript to a journal and...

Báo cáo sinh học: " Regulators of kinesin involved in polarized trafficking and axon outgrowth" potx

... protein Kinesin light chain Kinesin heavy chain Microtubules Figure Schematic diagram of a kinesin- cargo complex The cargo vesicles are thought to be associated with kinesins through the interactions ... the defects of Drosophila kinesin mutants in axonal transport, suggesting that UNC-76 coordinates with kinesin to regulate cargo trafficking in axons [23] The similarity of the unc-69 and unc-76 ... complexities of protein trafficking and targeting in developing axons References Tang BL: Protein trafficking mechanisms associated with neurite outgrowth and polarized sorting in neurons J Neurochem...

Báo cáo sinh học: "Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy" pptx

... repeats (ANK), a transactivation domain (TAD) and a PEST domain (P) TM, transmembrane domain (b,c) Two models for the roles of Ofut1 in Notch trafficking Each model is illustrated in a schematic ... (green) adapted from [19] The S2 cleavage site is indicated by an arrow The intracellular domain (NICD) contains various elements involved in transcriptional activation: a RAM domain, seven ankyrin ... Figure 1c) in which Ofut1 regulates the endocytic trafficking of Notch at a post-internalization step so that Notch accumulates in an undefined endocytic compartment in the absence of ofut1 activity...

Báo cáo y học: "Dynamic activation of bone morphogenetic protein signaling in collagen-induced arthritis supports their role in joint homeostasis and disease" ppsx

... Results Activation of bone morphogenetic protein signaling in collagen-induced arthritis Activation of BMP signaling during the course of CIA was visualized at different time points by immunohistochemistry ... likely to be influenced by the decreased number of cells in the cartilage, due to chondrocyte cell death during collagen-induced arthritis Activation of bone morphogenetic protein signaling in ... studied the role of BMP signaling in joint homeostasis and repair by modulating the BMP signaling pathway in different mouse models of chronic arthritis [23] NOG haploinsufficiency provided protection...

Báo cáo y học: "Endogenous and exogenous stem cells: a role in lung repair and use in airway tissue engineering and transplantation" pdf

... Kawashima H, Hatanaka A, Hoshi K, Ikada Y, Tabata Y, Iwanaka T: An animal model study for tissue- engineered trachea fabricated from a biodegradable scaffold using chondrocytes to augment repair ... 82 Omori K, Tada Y, Suzuki T, Nomoto Y, Matsuzuka T, Kobayashi K, Nakamura T, Kanemaru S, Yamashita M, Asato R: Clinical application of in situ tissue engineering using a scaffolding technique ... tissue engineering techniques and their careful evaluation in animal models of lung diseases and induced airway injury, have yielded the first successful clinical applications in lung repair The...

Báo cáo y học: " Effect of Ankaferd Blood Stopper on air leakage in the lung and prevention of bleeding: an experimental study" ppsx

... second In the standard surgery group (Group II), after having created an equal injury, the injury was sutured using 6-0 polyglactin (vicryl) Then the air leakage and bleeding were controlled and the ... investigating the effect of Ankaferd Blood Stopper on air leakage in the lung In our study, we investigated the air leakage repressive effect of ABS It prevents air leakage significantly compared to the ... parenchymal injury and a compress was applied and continuation of the air leakage and bleeding was monitored every seconds These durations were recorded The procedure was terminated at the 100 second...

Xem thêm

Từ khóa: the circuitry of the human spinal cord its role in motor control and movement disorders the role of oxidative stress in diabetic vascular and neural disease us air force views on arms control in the 1950s and early 1960s server s role in desktop control and management its role in pressure control and in hypertension potential role in human health and disease prevention the role of pro inflammatory cytokines in memory processes and neural plasticity selenoproteins in skeletal development and disease lessons from trsp deletion in murine bone and cartilage progenitor cells activity lags ligands for their ability in inhibit rat and human hsc trans differentiation proliferation into myofibroblasts b and naïve t cell differentiation the role of veterinary pharmacovigilance in risk analysis and the influence of risk perception on veterinary pharmacovigilance a european perspective on the role of information technology in genetic counselling ruth chadwick and kim petrie a new opinion on its nature parentage histogenesis cytomorphogenesis morphofunctional potency role in pathogenesis and morphogenesis of tuberculous process on the role of context and prosody the role of the courts in patent law and policy Nghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt nam Một số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTP Nghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THz Nghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt nam Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDE Phối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọ Nghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùng Nghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chế Nghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000 Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tin Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khí Tổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật Chiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015 QUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ