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Surface functionalization of superparamagnetic iron oxide nanoparticles for potential cell targeting, imaging, and cancer therapy applications

Surface functionalization of superparamagnetic iron oxide nanoparticles for potential cell targeting, imaging, and cancer therapy applications

Surface functionalization of superparamagnetic iron oxide nanoparticles for potential cell targeting, imaging, and cancer therapy applications

...     SURFACE FUNCTIONALIZATION OF SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES FOR POTENTIAL CELL TARGETING, IMAGING, AND CANCER THERAPY APPLICATIONS HUANG CHAO (B.ENG., ... Objectives and Scopes The overall aim of this thesis is to develop various functional polymers as surface coatings of SPIONs for potential cell targeting, MRI, and cancer therapy applications ... nanomaterials, magnetic iron oxide nanoparticles are of intense current interest and have been successfully used for clinical applications, for example, molecular imaging Magnetic iron oxide nanoparticles...
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báo cáo khoa học:

báo cáo khoa học: "Optimized labeling of bone marrow mesenchymal cells with superparamagnetic iron oxide nanoparticles and in vivo visualization by magnetic resonance imaging" ppsx

... as: Jasmin et al.: Optimized labeling of bone marrow mesenchymal cells with superparamagnetic iron oxide nanoparticles and in vivo visualization by magnetic resonance imaging Journal of Nanobiotechnology ... MSC Labeling and Proliferation Presence of iron nanoparticles within the cells was confirmed by staining with Prussian Blue (Figure 1A) or Figure Representative images demonstrating labeling of ... Bulte JW: Clinically applicable labeling of mammalian and stem cells by combining superparamagnetic iron oxides and transfection agents Radiology 2003, 228:480-487 Jasmin et al Journal of Nanobiotechnology...
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Microgel iron oxide nanoparticles for tracking of stem cells through magnetic resonance imaging

Microgel iron oxide nanoparticles for tracking of stem cells through magnetic resonance imaging

... Monocrystalline iron oxide nanoparticle MNC Mononuclear cells MMP Metalloproteinases MRI Magnetic resonance imaging MSC Mesenchymal stem cells PB Prussian blue PIO Primary iron oxide nanoparticle ... cells The aim of this thesis is to investigate the development of particulate cellular markers that will improve the tracking of stem cells in an animal model through MRI Current markers for cellular ... development of a high contrast MRI cellular label with superior performance over commericially-available iron particles, with possible applications for in vivo tracking of transplanted stem cells Acknowledgements...
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Báo cáo hóa học:

Báo cáo hóa học: " Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications" pdf

... first part of this work, we report fabrication of arrays of micro test tubes and microbeakers formed on p-type Si substrate with varying pore and particle sizes For the micro test tubes, the ... the micro test tubes and microbeakers on p-Si and analyses of the results SEM imaging was performed by AJ and MR SOR and ADG concentrated on the synthesis of SPIONs, magnetic characterization, and ... microbeakers and micro test tubes Based on the observations reported above we synthesized array of micro test tubes and microbeakers on p-Si substrate by suitably choosing the formation parameters...
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Báo cáo hóa học:

Báo cáo hóa học: " Iron Oxide Nanoparticles Employed as Seeds for the Induction of Microcrystalline Diamond Synthesis" pdf

... surfaces for the adsorption and decomposition of the incoming carboncontaining species, and thus for the formation of nanoscale The iron oxide nanoparticles were employed to induce the formation of diamond ... nanoparticles act as nucleation and aggregation sites for carbon and the impending formation of diamond- type bonds The formation of a dense, mixed C phase around the Fe nanoparticles leading to the precipitation ... that these serve as nucleation centers for subsequent growth [31] Thus the formation of a dense amorphous carbon phase is a plausible route for nucleating diamond The iron nanoparticle may act as...
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Formulation of superparamagnetic iron oxides by nanoparticles of biodegradable polymer for magnetic resonance imaging (MRI)

Formulation of superparamagnetic iron oxides by nanoparticles of biodegradable polymer for magnetic resonance imaging (MRI)

... some suggestions for future directions of this research are given Chapter Literature Review 2.1 Nanoparticles of Biodegradable Polymers 2.1.1 Basic information of Biodegradable Polymers Recently, ... of iron loading (% w/w) was calculated as the ratio of the mass of iron (mg) that can be detected using ICP analysis to the sum of the mass of iron (mg) and the mass of polymer (mg) 3.3.7 Magnetic ... are termed superparamagnetic iron oxides (SPIOs) where nanoparticles have a size greater than 50 nm (coating included) and the second type termed ultrasmall superparamagnetic iron oxides (USPIOs)...
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Báo cáo hóa học:

Báo cáo hóa học: " Synthesis of Organic Dye-Impregnated Silica Shell-Coated Iron Oxide Nanoparticles by a New Metho" doc

... preparing organic dye-impregnated silica shell-coated iron oxide nanoparticles based on the hydrolysis of HTMOS and TEOS Iron oxide nanoparticles were first coated with a dye-impregnated silica ... representative TEM images of iron oxide nanoparticles and FS6 nanoparticles prepared under different conditions As shown in Fig 2a, the majority of the iron oxide nanoparticles were spherical with an ... FS6 nanoparticles Figure gives the FT-IR spectra of neat Rhodamine 6G, silica- coated magnetic particles (denoted as FS nanoparticles) , and FS6 nanoparticles The absorption bands for neat Rhodamine...
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In vitro study of surface functionalization of titanium substrates for potential enhancement of osseointegration and reduction of bacterial infection

In vitro study of surface functionalization of titanium substrates for potential enhancement of osseointegration and reduction of bacterial infection

... IN VITRO STUDY OF SURFACE FUNCTIONALIZATION OF TITANIUM SUBSTRATES FOR POTENTIAL ENHANCEMENT OF OSSEOINTEGRATION AND REDUCTION OF BACTERIAL INFECTION HU XUEFENG (B.Eng., ... 2007).Therefore, new strategies of surface functionalization of titanium implants have been investigated with the aim of improving osseointegration 2.4.1 Enhancement of osseointegration by surface ... 2.4.1 Enhancement of osseointegration by surface topography 15 2.4.2 Enhancement of osseointegration by surface chemistry 16 2.5 Surface modification of Ti to reduce infections 22 2.5.1 Surface...
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Surface functionalization of titanium for biomedical applications

Surface functionalization of titanium for biomedical applications

... SURFACE FUNCTIONALIZATION OF TITANIUM FOR BIOMEDICAL APPLICATIONS ZHANG FAN (B.Eng.(Hons.), NUS) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF CHEMICAL AND ... initiator on titanium substrates This PhD project aims to modify titanium surfaces with a series of biologically active molecules to improve the performance of titanium substrates for biomedical applications ... solution of pH =2 at 37 °C for weeks 77 Figure 4-1 Schematic diagram illustrating the processes of silanization of the Ti-OH surface to give rise to the Ti-Cl surface, surface- initiated ATRP of HEMA...
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preparation and properties of magnetic iron oxide nanotubes

preparation and properties of magnetic iron oxide nanotubes

... sample S2 (c and d) and ␥-Fe2 O3 nanotubes in sample S3 (e and f) B Lv et al / Particuology (2008) 334–339 and outer and inner diameters of 70–120 nm and 45–80 nm, respectively Fig 3(c) and (d) show ... loop of ␥-Fe2 O3 nanotubes shows ferromagnetic behavior with a Ms of 42.71 emu/g, a Mr of 338 B Lv et al / Particuology (2008) 334–339 Fig M–H loops of Fe3 O4 nanotubes (a) and ␥-Fe2 O3 nanotubes ... López-Urías, and Mu˜ oz-Sandoval (2005) n simulated the micromagnetic property of iron nanorings, and they found large coercive fields for din /dout > 0.5 (din and dout are the inner and outer diameters of...
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Báo cáo hóa học:

Báo cáo hóa học: " Carbon-coated iron oxide nanoparticles as contrast agents in magnetic resonance imaging" potx

... the ferromagnetic iron oxide materials generally used for magnetic data storage as magnetic toners in xerography, and on the ferrofluids, used as contrast agents in magnetic resonance imaging [MRI] ... Carbon-coated iron oxide nanoparticles as contrast agents in magnetic resonance imaging Hongsub Bae1, Tanveer Ahmad1, Ilsu Rhee*1, Yongmin Chang2, Seong-Uk Jin2, and Sungwook ... iron oxide nanoparticles are applicable as both T1 and T2 contrast agents in magnetic resonance imaging Keywords: iron oxide nanoparticles; carbon-coated nanoparticles; relaxivity; MRI PACS: 81.05.y;...
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báo cáo hóa học:

báo cáo hóa học: " Beyond platinum: synthesis, characterization, and in vitro toxicity of Cu(II)-releasing polymer nanoparticles for potential use as a drug delivery vector" ppt

... the rate of Cu release (see Discussion) In vitro toxicity of CuCNPs in HeLa cells The in vitro toxicity of CuCNPs in HeLa cells (a cervical adenocarcinoma) was investigated via an assay based ... platinum: synthesis, characterization, and in vitro toxicity of Cu(II)-releasing polymer nanoparticles for potential use as a drug delivery vector Nanoscale Research Letters 2011 6:445 Submit your manuscript ... metal binding properties of our Cu-binding particles, as well as preliminary in vitro toxicity in cancer cells Page of 10 Results Synthesis and characterization of Cu-loaded polymeric nanoparticles...
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Engineering of binary metal oxide nanostructures for highly efficient and stable excitonic solar cells

Engineering of binary metal oxide nanostructures for highly efficient and stable excitonic solar cells

... bands of SnO2 flowers and fibers 137   6.1.7   Proposed growth model of nanoflowers 139   6.1.8   Fabrication of solar cells and evaluation of photovoltaic properties 142   6.2   Estimation of ... Outlook and Recommendations 162     Bibliography 164   vii SUMMARY Excitonic solar cells (ESCs) such as Dye Sensitized Solar Cells (DSCs) and Organic Solar Cells (OSCs) are promising candidates of ... energies of some of the organic components used in OSCs.[52] 23   Figure 1.14 Band energies of conduction band (CB) and valence band (VB) of different metal oxides.[75] 28   Figure 1.15 Schematic of...
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