... through an axon Most materials like tubulin, actin and neurofilamentous proteins are transported anterogradely from the perikaryon to the axon terminal at a fast and a slow rate In mammals, fast transport ... physiological and pathological processes In general, they are crucial participants in receptor-mediated intercellular signaling that regulate cells engaged in innate and adaptive immunity, inflammation, cell ... Watanabe, 1997), and activation of caspases, the final death pathway, to mediate apoptosis (Nishio and Watanabe, 1998) Through these mechanisms, NO appears to play a major role in the pathophysiology...