... injury model.Introduction Lung collapse is an important cause of deteriorated oxygena-tion and gas exchange after major surgery, in acute lung injury (ALI) and in acute respiratory distress syndrome ... wall elastance, as in this experiment,it should generate an adequate transpulmonary pressure forobtaining accurate TLC also after lung injury. Induction of lung injury Each animal was subjected ... [11,12,14,27].Our study has several limitations. First, it is an experiment in young previously healthy animals. Second, the lung collapseand lung injury are induced by surfactant deficiency andmechanical...