... resin by treatment with 1.5 mL of anisole,0.25 mL of dimethyl sulfide, and 10 mL of anhydrous HFper gram of peptide-resin for 1 h at 0 °C. After lyophiliza-tion of the extract, the crude peptide ... concentration of agonist A, in the presence of the antagonist B, which is equiactive to [A], the concentration of agonist in the absence of antagonist. Values presented are the mean ± SE of at least ... coupled manually to the resin. In order to obtain alower degree of substitution of the resin, 0.5 mmol of Na-Boc-Met per gram of resin was used for Na-Boc-Metcoupling, yielding after acetylation...