... autoantigen- presenting and stimulatory functions of the APCs necessary for activation and expansion of autoreactive Th1 and Th17 cells and B cells in lupus Apigenin also causes apoptosis of the hyperactive lupus APCs, ... stimulatory functions of the APCs necessary for activation and expansion of autoreactive Th and B cells, but it causes apoptosis of the hyperactive lupus APCs (this study), probably by inhibiting ... of various amounts of apigenin or vehicle solution After days of culture, supernatants were collected and assayed by ELISA for IgG antibodies against dsDNA, ssDNA, histones, and nucleosomes as...