... JournalOpen AccessResearch Involvement of PKR and RNase L in translational control and induction of apoptosis after Hepatitis C polyprotein expression from a Vaccinia virus recombinantCarmen ... Gómez, Andrée Marie Vandermeeren, Mar a Angel Garc a, Elena Domingo-Gil and Mariano Esteban*Address: Department of Molecular and Cellular Biology, Centro Nacional de Biotecnolog a, CSIC, Campus ... 8).Although the apoptotic levels induced by HCV proteinsremain invariable in PKR+ /+, PKR- /-, and RL+/+ cells, thelevels are significantly decreased in RL-/- cells, indicatingthat inducible expression...