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characterisation of the acto-myoa motor complex in toxoplasma gondii

Báo cáo khoa học: DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond pptx

Báo cáo khoa học: DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond pptx

... Fitz-gerald MC & Hendrickson WA (2007) Structural and thermodynamic characterization of a cytoplasmic dynein light chain intermediate chain complex. ProcNatl Acad Sci USA 104, 10028–10033.16 Hall ... and mediatesDNA damage-induced p53 nuclear accumulation.J Biol Chem 280, 8172–8179.11 Navarro C, Puthalakath H, Adams JM, Strasser A &Lehmann R (2004) Egalitarian binds dynein light chain to ... on the dynein motor complex Originally it was suggested that LC8 acts as a cargoadapter that links the cargo to the motor complex. However, DIC and Swallow, a cargo protein, occupy the very same...
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Báo cáo khoa học: Crystal structure of the parasite inhibitor chagasin in complex with papain allows identification of structural requirements for broad reactivity and specificity determinants for target proteases pptx

Báo cáo khoa học: Crystal structure of the parasite inhibitor chagasin in complex with papain allows identification of structural requirements for broad reactivity and specificity determinants for target proteases pptx

... FEBS Crystal structure of the parasite inhibitor chagasin in complex with papain allows identification of structural requirements for broad reactivity and specificity determinants for target proteases Izabela ... cystatin B N-terminus). (B) Zoom -in view of the interactions of papain with loop L6 of chagasin and loop L2 of cysta-tin B. (C) Zoom -in view of the interactions of papain with loop L4 of chagasin ... chagasin and the N-terminal segment of cystatin B. (D) Zoom -in view of the interactions of papain with loop L2 of chagasin and loop L1 of cystatin B.I. Redzynia et al. Chagasinpapain complex structure FEBS...
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Báo cáo khoa học: LIN54 is an essential core subunit of the DREAM / LINC complex that binds to the cdc2 promoter in a sequence-specific manner ppt

Báo cáo khoa học: LIN54 is an essential core subunit of the DREAM / LINC complex that binds to the cdc2 promoter in a sequence-specific manner ppt

... MYB1ATTTGAACTAGACCAATGCTGGGAGAAAAAATTTAAGATCTMut A ATTTGAACTGTGAAGATGCTGGGAGAAAAAATTTAAGATCTMut BMut CMut DATTTGAACTGTGCCAGGACTGGGAGAAAAAATTTAAGATCTATTTGAACTGTGCCAATGAGAGGAGAAAAAATTTAAGATCTATTTGAACTGTGCCAATGCTGAAGGAAAAAATTTAAGATCTATTTGAACTGTGCCAATGCTGGGAAGGAAAATTTAAGATCTATTTGAACTGTGCCAATGCTGGGAGAAGGGATTTAAGATCTATTTGAACTGTGCCAATGCTGGGAGAAAAAGGGTAAGATCTATTTGAACTGTGCCAATGCTGGGAGAAAAAATTGGGGATCTMut ... DATTTGAACTGTGCCAGGACTGGGAGAAAAAATTTAAGATCTATTTGAACTGTGCCAATGAGAGGAGAAAAAATTTAAGATCTATTTGAACTGTGCCAATGCTGAAGGAAAAAATTTAAGATCTATTTGAACTGTGCCAATGCTGGGAAGGAAAATTTAAGATCTATTTGAACTGTGCCAATGCTGGGAGAAGGGATTTAAGATCTATTTGAACTGTGCCAATGCTGGGAGAAAAAGGGTAAGATCTATTTGAACTGTGCCAATGCTGGGAGAAAAAATTGGGGATCTMut ... compilation ê 2009 FEBS LIN54 is an essential core subunit of the DREAM / LINC complex that binds to the cdc2 promoter in a sequence-specific manner Fabienne Schmit, Sarah Cremer and Stefan GaubatzDepartment...
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Báo cáo khoa học: Characterization of mutations in crucial residues around the Qo binding site of the cytochrome bc1 complex from Paracoccus denitrificans pdf

Báo cáo khoa học: Characterization of mutations in crucial residues around the Qo binding site of the cytochrome bc1 complex from Paracoccus denitrificans pdf

... despite the close prox-imity of the tyrosines to the Qo binding site. Most of the mutants studied here alter the spectral features of the quinone, indicating a variation of the hydrogen-bonding ... bc1complexes from other organisms. The mutated residues are highlighted in Fig. 1.Results Site- directed mutations in the Qo binding site Mutations in conserved positions of cytochrome b at the Qo site ... excess of stigmatellin.Upon binding of stigmatellin, shifts reflecting the changes within the binding site and the immediate envi-ronment are expected, together with signals for the inhibitor...
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Báo cáo khoa học: Analysis of the RNA degradosome complex in Vibrio angustum S14 potx

Báo cáo khoa học: Analysis of the RNA degradosome complex in Vibrio angustum S14 potx

... itsrole in mRNA degradation, the degradosome is alsoresponsible for the processing of 5S ribosomal RNA and tRNAs, as well as the degradation of tmRNAs [4–8]. The principal proteins comprising the degradosome include ... microdomains in the C-terminal half of Vibrio angustum S14 RNase E, and have shown through two-hybrid analy-sis that the PNPase and enolase-binding microdomains have protein-bind-ing function. ... for the V. angustum S14 RNA degradosome. We discuss the benefits of using Blue Native-PAGE as a toolto analyse the RNA degradosome, and the implications of microdomain-mediated RNase E interaction...
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Báo cáo khoa học: Interactions of the peripheral subunit-binding domain of the dihydrolipoyl acetyltransferase component in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus pot

Báo cáo khoa học: Interactions of the peripheral subunit-binding domain of the dihydrolipoyl acetyltransferase component in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus pot

... 2003 Thermodynamics of protein complex assembly (Eur. J. Biochem. 270) 4493 Interactions of the peripheral subunit-binding domain of the dihydrolipoyl acetyltransferase component in the assembly of ... Perham, R.N. (2002)Thermodynamic analysis of the binding of component enzymes in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus. Protein Sci. 11, 1091–1100.13. ... Competitiveinteraction of component enzymes with the peripheral subunit-binding domain of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus: kinetic analysis usingsurface...
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Báo cáo khoa học: Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides pptx

Báo cáo khoa học: Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides pptx

... between the RC and the cytbc1 in the presence of mutated PufX protein The role of the PufX protein in facilitating the ubiquinone/ubiquinol exchange between the QBsite of the RC and the ubiquinone ... important role in the structure of the core complex [12], we decided to investigate the possible structural role of the N-terminus and the C-terminus of PufX. To this aim, nine strains of Rb. sphaeroides ... residues and does not affect the photosynthetic growth of the bacterium. Overall, the resultspoint to a complex role of the N and C domains in the structural organization of the core complex; the N-terminusis...
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Báo cáo hóa học:

Báo cáo hóa học: " Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke" ppt

... this article as: Sun et al.: Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke. Journal of Translational ... Tracking of BrdU-labeled neural stem cells at passage six in the ischemic brain of rat having undergone cell therapy for fourweeks. A: a representative coronal section of a transplanted rat ... both the NSCcultures and the CSF of the rats. The immunochemical staining for MHC in brain sections and the enzyme-linkedimmunosorbent assay of CSF were carried out in sham-operated rats and rats...
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báo cáo hóa học:

báo cáo hóa học:" Function of anterior talofibular and calcaneofibular ligaments during in-vivo motion of the ankle joint complex" docx

... purposes)Journal of Orthopaedic Surgery and ResearchOpen AccessResearch article Function of anterior talofibular and calcaneofibular ligaments during in-vivo motion of the ankle joint complexRichard ... the position of the AJC was reproduced in the modeling soft-ware, the length of the ATFL and CFL was measured foreach testing position of AJC motion. There was no bonyinterference with the path of the ... However, the in-vivo behavior of the lateral ankle ligaments during the range of motion has not been well studied.Data in this study demonstrate that the ATFL lengthensmore in plantarflexion and...
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Báo cáo y học:

Báo cáo y học: "Critical role of the major histocompatibility complex and IL-10 in matrilin-1-induced relapsing polychondritis in mice" doc

... MIRPinduction, and IL-10 plays a major suppressive role in cartilageinflammation of the respiratory tract.Keywords: IL-10, matrilin-1, matrilin-1-induced relapsing polychondritis, major histocompatibility ... reported on the role of cytokines in RP,either in patients or in the corresponding animal models. In the CIA model, several cytokines have been shown to play major roles in the inflammatory process, ... articleCritical role of the major histocompatibility complex and IL-10 in matrilin-1-induced relapsing polychondritis in miceAnn-Sofie Hansson1, Åsa CM Johansson2 and Rikard Holmdahl21Department of...
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Báo cáo y học:

Báo cáo y học: " Characterisation of the immune response to type I collagen in scleroderma" pps

... 13-acetate)/ionomycin activated T cells. (a) We detected interferon (IFN)-γ staining but no interleukin (IL)-4 staining. Mul-tiplex cytokine assay was used to analyse the cytokine profile of three ... (CI)-responsive T-cell linesTh1 polarisation of type I collagen (CI)-responsive T-cell lines. Cytokine expression of T-cell lines was determined by intracellular (IC) staining of PMA (phorbol 12-myristate ... importance of immunity to CI is emphasised by the finding that oral administration of CI to patients with SScmodulates T-cell responses and may ameliorate the disease[15]. Similar findings have...
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Báo cáo y học:

Báo cáo y học: "Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis" pdf

... simply reflect the level of synthesis/release and catabolism of endocannabinoids and entourage compounds in the synovium. The source of the endocannabinoids present in the synovium and synovial fluid ... Representativemicrographs of this grading system are presented in Figure 1.Quantification of inflammatory cytokines in synovial fluid Cytokine profiles in synovial fluid were determined using aBD™ cytometric ... 1. Patients were told to stop taking aspirin and all cytokine inhibitors 10to 14 days prior to surgery.Histology of synovial biopsies and levels of cytokinesHaematoxylin and eosin histology...
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Báo cáo khoa học:

Báo cáo khoa học: "Characterisation of the Repeat Breeding Syndrome in Swedish Dairy Cattle" ppt

... lactation. In conclusion our results show that the repeat breeding syndrome is a multifactorial problem involving a number of extrinsicfactors as well as intrinsic factors coupled to the individual ... re-flected in the present study showing that ani-mals getting their first insemination during Jan-uary have higher risk of becoming RB animals. In agreement with our findings, Hewett (1968)found the ... frequency of RB is graphically exemplified in Fig. 1, show-ing that the frequency of RB is increasing by in- creased SCC and the increase is greater in larger herds than in smaller. As shown in Fig....
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Báo cáo sinh học:

Báo cáo sinh học: " Genetic and morphological characterisation of the Ankole Longhorn cattle in the African Great Lakes region" pptx

... 0.01, and ***P < 0.001. Genetic and morphological characterisation of the Ankole cattle 471 Original article Genetic and morphological characterisation of the Ankole Longhorn cattle in the African ... disease and other stresses in improvement of ruminant livestock in the tropics, in: Proceedings of the 5th Genetic and morphological characterisation of the Ankole cattle 487 at TGLA122 , while the ... corresponding to the square root of the sum of the squared dis-tances between the centroid (i.e. centre of gravity of the landmarks) and each of the c onfigured landmarks. Then, the centroids of all...
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characterisation of the acto-myoa motor complex in toxoplasma gondii

characterisation of the acto-myoa motor complex in toxoplasma gondii

... referring to this work, full bibliographic details including the author, title, awarding institution and date of the thesis must be given Characterisation of the Acto-MyoA motor complex ... Myosin A motor complex. This complex consists of the myosin heavy chain A (MyoA), the myosin light chain 1 (MLC1), the essential light chain 1 (ELC1) and three gliding-associated proteins (GAP40, ... assembly of the cytoskeleton 191.7 Myosin motor complexes 211.7.1 Motor proteins in general 211.7.2 General overview and structure of myosins 221.7.3 Myosins in Apicomplexa 221.7.4 Myosin A motor...
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