... initial and final anisotropy signals. For all reactions tested, full saturation was achieved at a 1 : 1 molar ratio of titrant,indicating a 1 : 1 stoichiometry, which validates the use of a 1 ... large T antigen (SV40LT) and adenovirus E 1A (AdE 1A) also target the Rb protein and sharesequence and functional conservation with the HPVE7 protein [21,22]. E7, AdE 1A and SV40LT each con-tain ... increased amount of disorder in E6 and E7oncoproteins from high risk HPVs. J Proteome Res 5,1829–1842.32 Alonso LG, Garcia-Alai MM, Nadra AD, Lapena AN,Almeida FL, Gualfetti P & Prat-Gay...