TARGETING ACUTE PHOSPHATASE PTEN INHIBITION AND INVESTIGATION OF A NOVEL COMBINATION TREATMENT WITH SCHWANN CELL TRANSPLANTATION TO PROMOTE SPINAL CORD INJURY REPAIR IN RATS
TARGETING ACUTE PHOSPHATASE PTEN INHIBITION AND INVESTIGATION OF A NOVEL COMBINATION TREATMENT WITH SCHWANN CELL TRANSPLANTATION TO PROMOTE SPINAL CORD INJURY REPAIR IN RATS
... Microtubule-associated protein light chain 3 II. iv ABSTRACT Chandler L. Walker TARGETING ACUTE PHOSPHATASE PTEN INHIBITION AND INVESTIGATION OF A NOVEL COMBINATION TREATMENT WITH SCHWANN ... SCHWANN CELL TRANSPLANTATION TO PROMOTE SPINAL CORD INJURY REPAIR IN RATS Human traumatic spinal cord injuries (SCI) are primarily incomplete contusion or compression injuries at the cervical ... through delayed cell death mechanisms such as apoptosis and autophagy. As such, understanding the dynamics of cervical SCI and related intracellular signaling and death mechanisms is essential. ...
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Báo cáo khoa học: cDNA cloning and characterization of a novel calmodulinlike protein from pearl oyster Pinctada fucata potx
... using a pair of specific primersP3 (5¢-GGAAGAATACAGACACGGACAG-3¢) and P4(5¢-ATAACAACAGTTTATACATCGCTTC-3¢) correspon-ding to the 5¢-untranslated and 3¢-untranslated regions of oyster CaLP mRNA, ... CaLP and CaM appeared as a single band with an apparentmolecular weight of approximately 18 kDa and 14 kDa, respectively, whereas in the absence of cal-cium, the apparent molecular mass was ... Comparison of the amino-acid composition of the calcium-binding domains in canonical EF-hands [30] with that in the EF-hands in oyster CaLP, reveals a good correlation of Ca2+-bind-ing ligand...
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Báo cáo khoa học: Detection and characterization of a novel extracellular fungal enzyme that catalyzes the specific and hydrolytic cleavage of lignin guaiacylglycerol b-aryl ether linkages pdf
... Ikeda1, Shinya Kajita1, Masaya Nakamura2 and Yoshihiro Katayama11Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo,Japan;2Forestry ... notattack b-aryl ether linkages in high-molecular mass mate-rials in vivo because it acts at the intramolecular level and cannot gain access to the b-aryl ether linkages in high-molecular mass ... other aromatic side chains to form free radicals.Although this acts to cleave Ca-Cb linkages and b-O-4linkages in the lignin structure, the free radicals causerandom depolymerization of lignin....
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Báo cáo khoa học: Cloning, characterization and localization of a novel basic peroxidase gene from Catharanthus roseus potx
... 1297Cloning, characterization and localization of a novel basicperoxidase gene from Catharanthus roseusSantosh Kumar, Ajaswrata Dutta, Alok K. Sinha and Jayanti SenNational Centre for Plant Genome ... (AAD33072), cotton (COTPROXDS) (AAA99868), barley grain (BP1) (AAA32973),Ar. thaliana (ATP 2A) A2 (Q42578) and HRP-C (AAA33377). Residue numbers start at the putative mature proteins by analogy with HRP-C.Preprotein ... paren-chymatous and stomatal guard cells, CrPrx–GUS–GFP was found to be accumulated mostly in the cell walls, outer cell membranes and associated structures(Figs 8A, B and 9A, B). On detailed examination,CrPrx–GFP...
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Báo cáo Y học: Identification and characterization of a novel activated RhoB binding protein containing a PDZ domain whose expression is specifically modulated in thyroid cells by cAMP pot
... cubical epithe-lial morphology correlated with a profound redistribution of both actin microfilaments and cytokeratin intermediatefilaments, and with the appearance of a marked cytokeratin and actin ... Fujisawa, K., Okawa, K., Iwamatsu, A. ,Fujita ,A. ,Watanabe,N.,Saito,Y.,Kakizuka ,A. ,Morii,N.&Narumiya, S. (1996) The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein ... obtained a light diffuse cytoplasmicstaining with a clear perinuclear accumulation (Fig. 4B).Moreover p76RBEis, at least partially, located in the cell plasma membrane as indicated by arrows...
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Báo cáo khoa học: Proteome analysis of a rat liver nuclear insoluble protein fraction and localization of a novel protein, ISP36, to compartments in the interchromatin space pptx
... 635–644.10 Jagatheesan G, Thanumalayan S, Muralikrishna B,Rangaraj N, Karande AA & Parnaik VK (1999) Colo-calization of intranuclear lamin foci with RNA splicingfactors. J Cell Sci 112 ... pro-tein that associates with nuclear matrix. DNA Cell Biol17, 849–858.24 Lee JY, Nakane Y, Koshikawa N, Nakayama K,Hayashi M & Takenaga K (2000) Characterization of a zinc finger protein ZAN75: ... 23 and 25, were lamin A, lamin C, lamin B1, vimentin,keratin type 2, keratin type 1 and actin, respectively,which are all filament proteins. Uricase (band 15 in Fig. 1B) probably represented a...
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báo cáo hóa học: " The design and testing of a novel mechanomyogram-driven switch controlled by small eyebrow movements" docx
... corresponding to thebaseline MMG signals and γ is the threshold-scaling fac-tor.The scaling-factor γ could be varied between 1.2 and 2.5 in increments of 0.2. The value of j was set to 1. CWTanalysis ... quick and sustained eye-brow raises, eye blinks and head move-ment.JNERJOURNAL OF NEUROENGINEERING AND REHABILITATIONAlves and Chau Journal of NeuroEngineering and Rehabilitation 2010, 7:22http://www.jneuroengrehab.com/content/7/1/22Open ... buttons to brain-computer interfaces [2]. Often, individuals who areseverely disabled may retain the ability to contract certainmuscles. For example, individuals with high-level spinal cord...
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báo cáo hóa học: "Initial development and testing of a novel foam-based pressure sensor for wearable sensing" doc
... time. In a garment-inte-grated context, washability of components is important to the preservation of normal user patterns of care and main-tenance of clothing. In the torso integration, the raw ... polymers are attractive for sensing in a gar-ment-integrated context because of their ability to retainthe tactile and mechanical properties of a textile-basedstructure. In the garment integration, ... the foam,it was applied to the wearable environment to explore itsutility in garment systems. It was integrated into a torsogarment in several ways to investigate the ability of thefoam sensor...
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báo cáo hóa học:" Biomechanical investigation of a novel ratcheting arthrodesis nail" ppt
... distinct advantage in the ratchetingmechanism when compared to the currently clinicallyavailable nails. With sufficient axial load, the ratchet willadvance. Therefore, it will always maintain ... further investigated.ConclusionThis data, while preliminary, suggests that a ratchetingdevice may have useful clinical applications. A statisti-cally significant inc rease in the load maintained ... then calculated for each of the three naildesigns (Table 1) and standard deviation was alsocalculated.Stress shielding data were also calculated by recordingthe maximum load applied to the...
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báo cáo hóa học:" Biomechanical investigation of a novel ratcheting arthrodesis nail" pot
... average percent of initial load was then calculated for each of the three naildesigns (Table 1) and standard deviation was alsocalculated.Stress shielding data were also calculated by recordingthe ... novel ratcheting nail was designed and mechanically tested in comparison to a solid nail and a threaded nail using sawbones models (Pacific Research Laboratories, Inc.). Intramedullary nails (IM) ... contributed to the data collection/interpretation,mechanical testing and drafting/revising of the manuscript. DW and KB havecontributed to the mechanical testing and mechanical evaluation of thefusion...
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