... synthase 2 promoterpolymorphisms and systemic lupus erythematosus in African-Americans.J Rheumatol 2003, 30:6 0-6 7.40. Martin-Donaire T, Losada-Fernandez I, Perez-Chacon G, Rua-Figueroa I,Erausquin ... 58:338 8-3 393.42. Khani-Hanjani A, Lacaille D, Hoar D, Chalmers A, Horsman D, Anderson M,Balshaw R, Keown PA: Association between dinucleotide repeat in non-coding region of interferon-gamma gene and susceptibility ... mostprominent being the kidneys, joints, skin and brain [1].The major determinant of morbidity and mortality isrenal involvement, although infection and cardiovasculardisease are leading causes...