Báo cáo y học: "Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues" ppt
Báo cáo y học: "Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues" ppt
... withdetailed expression profiles for 17,330 genes across all the 9,783 annotated healthy and pathological human samples. We provide the possibility to analyze the levels of gene expression across all ... Biology 2008, 9:R139Open Access2008Kilpinenet al.Volume 9, Issue 9, Article R139MethodSystematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 ... meth-odology is that it provides an integrated view of human gene expression levels across thousands of samples representinghundreds of different tissue and disease types. GeneSapiensoffers unprecedented...
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Báo cáo y học: " C-reactive protein does not opsonize early apoptotic human neutrophils, but binds only membrane-permeable late apoptotic cells and has no effect on their phagocytosis by macrophages" pot
... Dransfield I:Phagocytosis of apoptotic cells by human macrophages: Analysis by multiparameter flow cytometry. Cytometry 2003,51A:7-15.16. Hebert MJ, Takano T, Holthofer H, Brady HR: Sequential morpho-logic ... detection of ligand binding to neutrophils by using a preparation of directly labelled CRP that we have shown was essentiallyfree of contaminating IgG, but which was structurally and functionally intact. ... SanFrancisco, USA [13]. Surface phenotyping using indirectimmunofluorescence and flow cytometry confirmed expression of FcγRIIA by the transfected cells, but no expression of FcγRI or FcγRIII was detected....
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Báo cáo y học: "Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis" pdf
... studies.Materials and methodsQUOROM (quality of reporting of meta-analyses) and MOOSE (meta -analysis of observational studies in epidemiol-ogy) guidelines were followed where applicable [19,20]. Stud-ies of ... http://arthritis-research.com/content/8/6/R182Page 1 of 10(page number not for citation purposes)Vol 8 No 6Research articleSystematic review and meta -analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus ... remission of lupusnephritis in systemic lupus erythematosus. Evidence about itsuse was sought from full publications and abstracts of randomised trials and cohort studies by using a variety of searchstrategies....
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Báo cáo y học: "Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action" pot
... Snyder M, Oliver SG, Cyert M, Hughes TR, Boone C, Andrews B: Mapping pathways and phenotypes by systematic gene overexpression. Mol Cell 2006, 21:319-330.Hillenmeyer et al. Genome Biology ... struc-tural similarity (295 and 37 pairs in the heterozygous and homozygous datasets, respectively). Of these pairs, 74% and 90% in the heterozygous and homozygous datasets,respectively, did not share ... 126:611-625.7. Dudley AM, Janse DM, Tanay A, Shamir R, Church GM: A global view of pleiotropy and phenotypically derived gene function in yeast. Mol Syst Biol 2005, 1:. 2005.00018. Fry RC, Begley TJ, Samson...
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Báo cáo y học: "Systematic analysis of transcribed loci in ENCODE regions using RACE sequencing reveals extensive transcription in the human genome" pptx
... tiling arrays. It isthus likely that many (and possibly the majority) of known genes are expressed and spliced in human tissues and celllines, and that multiple transcripts are produced from mostgene ... namely SYN3 and TIMP3, in cells in which their expression was notdetected by tiling microarray analysis. SYN3 and TIMP3 areencoded on opposite strands from one another on chromo-some 22. SYN3 ... RNA isoforms suggeststhat additional messages are probably produced from eachgene locus.To gain a better understanding of why the SYN3 and TIMP3 genes were not detected by microarray analysis, ...
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Báo cáo y học: "Systematic analysis of gene expression in human brains before and after death" docx
... postmortem human brains. Study of expression levels of 14 genes in human brain autopsy and biopsy samples found significant change in one of the genes, indicating that asubstantial proportion of all ... expressed genes could beaffected by death [10].We surveyed gene expression in 10 postmortem human brain samples (autopsy samples) and 12 samples obtained from brain surgery (resection samples) ... duration of postmortem interval and themagnitude of expression differences between autopsy and postmortem samples. This suggests that expression changesoccur quickly in the process of dying and...
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Báo cáo y học: "Segment-orientated analysis of two-dimensional strain and strain rate as assessed by velocity vector imaging in patients with acute myocardial infarction"
... strain analysis of the global and regional myocardial function for the differentiation of pathologic and physiologic left ventricular hypertrophy: A study in athletes and in patients with hyper-trophic ... superiority of a combined assessment of the systolic and early diastolic mitral annular velocities by tissue Doppler imaging for the differenti-ation of restrictive cardiomyopathy from constrictive ... A cut-off value of –10.34% resulted in a sensitivity of 54 % and specificity of 59 % (see Table 6). The intra- and inter-observer variation of our data is congruent with the data of Jarnert...
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Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"
... (Affymetrix). DNA microarray analysis Data analyses were performed using the GeneChip Expression Analysis Software (version 3.2, Affymetrix). First, single array analysis was performed [11] ... Additionally, we evaluated the functional pathways in which the ethanol-regulated genes were involved using KEGG (Kyoto Encyclopedia of Genes and Genomes) [36] and GenMAPP (Gene Microarray Pathway ... by cDNA microarray analysis. Hepatology 2001;33:676-91. 14. Okabe H, Satoh S, Kato T, et al. Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray:...
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Báo cáo y học: "A comparative analysis of antibody repertoire against Staphylococcus aureus antigens in Patients with Deep-Seated versus Superficial staphylococcal Infections"
... measurement of IgG antibodies to peptidoglycan and teichoic acid in sera from patients and healthy controls was checked by ELISA. The sera obtained from both patients and healthy controls ... cell lysate of Staphylococcus aureus during infection was examined qualitatively by immunoblot analysis of sera from patients of both the group. Figure 2 shows the IgG immunoblot profile of ... Figures Table 1. IgG antibody levels against PG and TA in sera from healthy individuals and patients with deep-seated and superficial staphylococcal infections. Healthy Individuals (n = 15)...
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Báo cáo Y học: Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN Design of a potent endozepine antagonist pot
... residue[38,39]. Analysis of hydrogen bonds and dihedral angles(F, C) for the average structures generated from members of cis and trans family of cyclo128[D-Leu5]OP showed thatthe residues of the cis and ... N,N-diiso-propylethylamine (DIEA) were purchased from AppliedBiosystems (St Quentin en Yvelines, France). Preloaded poly(ethylene glycol)–polystyrene resin [Fmoc-Asp(PEG-PS)-OAl] was obtained from ... of experiments [25].RESULTSSynthesis of cyclic peptidesThe two cyclic peptides cyclo128OPandcyclo128[D-Leu5]OPwere synthesized directly on solid support and the head-to-tail cyclization was achieved...
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