Báo cáo y học: "Crops in all shapes and sizes " ppt
Báo cáo y học: "Crops in all shapes and sizes." ppt
... copy, culminating in an elongated fruit shape. Thisdiscovery shows that retrotransposons may be a majordriving force in genome evolution and gene duplication,resulting in phenotypic changes in ... ttoommaattoo ffrruuiitt mmoorrpphhoollooggyyEdible fruits are markedly diverse in size and shape.Breeding and mutation analysis in tomato have resulted in adiverse collection of germplasm, which ... regulation ofmetabolism during fruit ripening have been found. Candi-date genes are being evaluated by a combination of virus-induced gene silencing and transgenesis. An integrated viewof tomato...
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Báo cáo y học: "Drugs in development: bisphosphonates and metalloproteinase inhibitors" potx
... is being directedtowards the role of cytokines and signalling pathways in the regulation of the MMPs in disease. Blocking of certaincytokines or inhibiting the inflammatory cell signalling path-ways ... tissues bybinding to hydroxapatite but that orally administeredpyrophosphates are hydrolysed in the gut. Bisphospho-nates are resistant to hydrolysis and so could be adminis-tered orally [12]. ... the cytokine signalling pathways[130]. Finally, there is interest in the synthesis of modifiedTIMPs that are specifically targeted to inhibit specificenzymes [131–133].It is interesting that,...
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Báo cáo y học: "Developments in the scientific and clinical understanding of the spondyloarthritides" pptx
... respectively) ofclinical symptoms. Andrei Calin, of Bath, UK, had started thiskind of work in the early 90s with the definition of the BathAnkylosing Spondylitis Disease Activity Index (BASDAI) ... Ankylosing Spondylitis Functional Index (BASFI), and the Bath Ankylosing Spondylitis Metrology Index (BASMI) (all on a scale between 0 = no change and 10 = worstchange), which are all still in ... last 10 years both in the clinical and scientific understanding of the spondyloarthritides(SpA), which can be separated in predominantly axial and predominantly peripheral SpA. The clinical progress...
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Báo cáo y học: "Developments in the scientific and clinical understanding of autoinflammatory disorders" doc
... generically as a pyrin domain (PYD) in other proteins that have homology with pyrin’s N-terminalsequence [12]. Members of the death domain superfamily areinvolved in the assembly and activation ... exceptionally rare autosomal dominant disease is causedby mutations in the proline serine threonine phosphatase-interacting protein-1 (PTSTPIP) gene encoding a protein alsoknown as CD2-binding ... expression and thereby increases IL-1 gene expression. IL-1 is a majorproinflammatory cytokine that mediates a multitude of local and systemic responses to infection and tissue injury and, asproved by...
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Báo cáo y học: "Developments in the scientific and clinical understanding of inflammatory myopathies" pps
... polymyositis or dermatomyositis,which makes IFN-α a potential specific target for therapy in these patients.Cytokines, chemokines, and prostaglandinsProinflammatory cytokines, chemokines, and ... cells in myositis are insufficient and this needsfurther investigations.Dendritic cell expression and the type Iinterferon systemRecently, DCs were reported in muscle tissue of polymyositis and ... idiopathic inflammatory myopathies, collectively calledmyositis, constitute a heterogeneous group of chronic dis-orders sharing the predominating clinical symptom of muscleweakness and, in classical...
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Báo cáo y học: "Developments in the scientific and clinical understanding of gout" docx
... Research & Therapy Vol 10 No 5 Sotions for these findings include lifestyle and dietary changesbrought about by increasing prosperity and increased lifeexpectancy and age of the population.Uric ... mediators.Experimentally, the uptake of MSU crystals by monocytes involvesinteractions with components of the innate immune system, namelyToll-like receptor (TLR)-2, TLR-4, and CD14. Intracellularly, MSUcrystals ... asHGPRT (hypoxanthine-guanine phosphoribosyl transferase)deficiency and PRPP (phosphoribosylpyrophosphate) synthe-tase overactivity, account for but a small fraction of cases ofhyperuricemia and...
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Báo cáo y học: "Developments in the scientific and clinical understanding of fibromyalgia" pdf
... provides clinicallymeaningful benefit to patients with FM. In another study Mease and colleagues evaluated the safely and efficacy of milnacipran, a dual norepinephrine and serotonin reuptake inhibitor ... through the activity of inhibitory neurotransmitters, whichinclude serotonin, norepinephrine, enkephalins, γ-aminobutyric acid and adenosine. A decrease in this pain inhibitoryloop is an important ... duloxetine60 mg twice daily had significantly greater improvement in remaining Brief Pain Inventory pain severity and interferencescores, Fibromyalgia Impact Questionnaire scores, ClinicalGlobal Impression...
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Báo cáo y học: " Alterations in hippocampal serotonergic and INSR function in streptozotocin induced diabetic rats exposed to stress: neuroprotective role of pyridoxine and Aegle marmelose" doc
... Receptor Binding Studies Using [3H]5-Hydroxytryptamine5-HT receptor assay was done using [3H] 5-hydroxy-tryptamine binding in crude synaptic membrane pre-parations of hippocampus by the modified ... potentiating of insulin effect ofplasma by increasing the pancreatic secretion of insulinfrom existing b-cell or its release from bound insulinintercede by increase in t he insulin receptor. ... marmelose and Syzygium cumini by activation of Glut-4, PI3 kinase and PPARγ in L6myotubes. Phytomedicine 2006, 13:434-441.47. Panda S, Kar A: Evaluation of the antithyroid, antioxidative and antihyperglycemic...
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Báo cáo y học: "Contraception in HIV-positive female adolescents." ppt
... therapy (HAART), an increas-ing number of children, infected perinatally, are survivinginto adolescence. Adolescents with perinatally acquiredHIVinfectionsarebecomingsexually active and are in need ... administered RTV, as a single PI in healthyvolunteers, in gradually increasing doses for 30 daysfrom 300 mg to 500 mg twice daily. At the same timeon da y 1 and day 29, 0.05 mg of EE was administered.The ... notsubstantially different from that of HIV-uninfected peers. Because of highly active antiretroviral therapy, increasingnumber of children, infected perinatally, are surviving into adolescence and...
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Báo cáo y học: "Variations in brachial plexus and the relationship of median nerve with the axillary artery: a case report." pps
... artery anteriorly may cause compression syn-dromes producing ischemia.The subclavian and axillary system of arteries is derivedfrom the seventh cervical intersegmental artery. Hence,the artery ... [12]. In a study doneby Pandey and Shukla on 172 cadavers, in 8 cadavers, themedian nerve was formed medial to the artery and traveled as such [13]. Anomalous branches of lateral cordcrossing ... is innervated directly from the bra-chial plexus, from the upper and middle trunks. Normallyit is supplied by the axillary nerve.The relationship of the axillary artery is not normal. In ourcase,...
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