Báo cáo y học: "Deafblindness in French Canadians from Quebec: a predominant founder mutation in the USH1C gene provides the first genetic link with the Acadian population" ppsx

... the Acadians and French Canadians from Quebec are descended from French ancestors, they havealways been considered genetically distinct. The genetic conditions common in Quebec aregenerally ... Mustapha M, Kikkawa Y, Laine S,Delmaghani S, Adato A, Nadifi S, Zina ZB, et al.: Usher syndrometype I G (USH1G) is caused by mutations in the gene encod-ing SANS, a protein that associates with ... mutation in the USH1C gene provides the first genetic link with the Acadian populationInga Ebermann*, Irma Lopez†, Maria Bitner-Glindzicz‡, Carolyn Brown†, Robert Karel Koenekoop† and...

Báo cáo y học: "Renal impairment after switching from stavudine/ lamivudine to tenofovir/lamivudine in NNRTIbased antiretroviral regimens" docx

... of the renal impairment in tenofovir-containing backboneNRTI plus nevirapine on this aspect are warranted. In addition, a pharmacogenetic study revealed that poly-morphisms in the ABCC2 gene ... demographicsand genetics may play role on the frequency of theseTable 3 Univariate and multivariate analysis of possible factors associated with low eGFR at week 24 afterswitching NRTIParameters ... common in HIV-infected patients, other secondary causes ofincrease in urinary loss in these stable patients with nor-mal renal function are unlikely.Tenofovir-associated renal dysfunction can...

Báo cáo y học: "Wound trauma mediated inflammatory signaling attenuates a tissue regenerative response in MRL/MpJ mice" pot

... The mechanism(s) involved areunclear, but it appears that the anatomical site of the injury, the severity of the injury, and the milieu of pro- oranti-inflammatory cytokines are all critical ... and infiltra-tion of macrophage and neutrophils. These observationslead us to speculate that macrophage hyperactivity afterthermal injury may play a critical role in altered ear-holehealing ... excluded from the study. Typically, in non-injuredmice, the circular wounds healed in a circular fashionwhereby the mean hole diameter was calculated by taking the average of the longest and the...

Báo cáo y học: " Wound trauma mediated inflammatory signaling attenuates a tissue regenerative response in MRL/MpJ mice" ppsx

... The mechanism(s) involved areunclear, but it appears that the anatomical site of the injury, the severity of the injury, and the milieu of pro- oranti-inflammatory cytokines are all critical ... attenuated early ear wound healing in the thermally injured mouse resulted in incomplete tissue regeneration in addition to a marked inflammatory response, as evidenced by the histological appearance ... placedalone in separate cages and maintained under standardconditions in the animal facility (as described above).Zins et al. Journal of Inflammation 2010, 7:25http://www.journal-inflammation.com/content/7/1/25Page...

Báo cáo y học: "Cancer risks of dermatomyositis and polymyositis: a nationwide cohort study in Taiwan" pps

... study was based on data from the NationalHealth Insurance Research Database released by the National Health Research Institute. Taiwan began itsNational Health Insurance program in 1995 to financehealthcare ... obtained from the Registry of Cata-strophic Illness Database, a subpart of the NationalHealth Insurance Research Database. The insured whosuffer from major diseases can apply for a catastrophic ... Personal information, including family history,lifestyle and habits such as smoking and alcohol use, wasnot available from the National Health InsuranceResearch Database.Study subjectsAll...

Báo cáo y học: " Mixed infection and clonal representativeness of a single sputum sample in tuberculosis patients from a " docx

... strain at anygiven time, and (ii) that an isolate from a single sputumspecimen is representative of the total bacillary popula-tion in a patient. Therefore, we systematically compared the genetic ... latter case was based on the fact that one of the isolates from the latter patient hadidentical DNA fingerprinting patterns with an isolate from another patient processed on the same day. Thus, ... that if only the first pre-treatment sample was analysed by standard IS6110 finger-printing or by MIRU-VNTR typing, none or only abouthalf of the mixed infection cases detected by analysis ofmultiple...

Báo cáo y học: " Cardiovascular stability during arteriovenous extracorporeal therapy: a randomized controlled study in lambs with acute lung injury" docx

... safety and efficacy of AV-ECMOtherapy in a phase I clinical study. They treated eight patients(five males and three females, aged 21–67 years), who hadacute respiratory failure and hypercapnia, ... may a short recovery period after ALI affect hemody-namic stability during an AV-ECMO operation? ALI leads to the release of a variety of bioactive materials, includingproinflammatory cytokines ... separate lavages and intratracheal instillation of 2.5 ml/kg of 0.1 N HCl (fractional inspired oxygen 0.6)Changes in the average alveolar–arterial oxygen (A- a O2) gradient, pul-monary artery...

Báo cáo y học: " Keratin 19 marks poor differentiation and a more aggressive behaviour in canine and human hepatocellular tumours" pptx

... Early hepatocellularcarcinoma as an entity with a high rate of surgical cure. Hepatology1998, 28:1241-1246.6. Imamura H, Matsuyama Y, Tanaka E, Ohkubo T, Hasegawa K, Miyagawa S,Sugawara Y, ... study paraffin m aterial of a wide variety of pri-mary liver tumours was available from the paraffinmaterial archive present at the department of Patho-biology, Faculty of V eterinary Medicine, ... finally counterstained with Maye r’shema-toxylin (Mayer’s haematoxylin, Klinipath B .V. Duiven, The Netherlands). Negative controls were perfor med byreplacing the primary antibody with washing...

Báo cáo y học: "Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute" potx

... present.On the other hand, MSCs may also actively participate in initiating AD [3], they have the potential to favour spread ofmelanoma metastases [4] and, although mostly immuneprivileged, they may ... modulatedsuccessfully in case reports and small series, with apparentlylow acute toxicity [57,63]. Long-term safety data are needed.Scanty and sometimes contradictory AD animal data areavailable. Although the ... workers in the fields of MSCbiology and AD in order to define areas of potential synergyand interdisciplinary collaboration. As pointed out by the director of the institute, Marc Feldmann, following...

Báo cáo y học: "Characterization of Human Erythrocytes as Potential Carrier for Pravastatin: An In Vitro Study"

... of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia  Corresponding author: Fars K. Alanazi, Kayyali Chair for Pharmaceutical Industry. afars@ksu.edu.sa ... morphology[13]. Pravastatin release Figure 4 shows that the pravastatin release pat-tern from loaded erythrocytes in PBS, plasma and PBS after using glutaraldehyde as a membrane stabilizer. Also the figure ... SEM. The re-sults revealed that pravastatin was loaded success-fully on human erythrocytes with acceptable loading parameters. Pravastatin releases from loaded eryth-rocytes obeying first...

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