Báo cáo y học: "Kappa-alpha plot derived structural alphabet and BLOSUM-like substitution matrix for rapid search of protein structure database" ppsx
Báo cáo y học: "Kappa-alpha plot derived structural alphabet and BLOSUM-like substitution matrix for rapid search of protein structure database" ppsx
... improve the ability of BLAST to search for structural homology of a query sequence to a known protein structure or a family of proteins. This tool searches for the structural alphabet high-scoring ... basis, and effective and reliable search capabilities) and employs a kappa-alpha (κ, α) plot derived structural alphabet and a new substitution matrix. 3D-BLAST searchesmore than 12,000 protein structures ... structural alphabet and BLOSUM-like substitution matrix for rapid search of protein structure databaseChi-Hua Tung¤*, Jhang-Wei Huang* and Jinn-Moon Yang¤*†‡Addresses: *Institute of Bioinformatics,...
- 16
- 267
- 0
Báo cáo y học: " Inflammatory parameters predict etiologic patterns but do not allow for individual prediction of etiology in patients " ppsx
... Thestudy monitor of the LCC includes the patient in CAP-NETZ by applying the following criteria: age ³ 18 years, apulmonary infiltrate diagnosed by chest x-ray, clinicalsymptoms consisting of ... study. The study was approved by the local eth-ical committee. Our study was not an intervention studywith implementation of standardized criteria for the diag-nosis and therapy of CAP according ... diagnosticsAt the point of inclusion into the study blood sampleswere taken for the determination of PCT, CRP and WBC,blood culture and serological testing for Chlamydia pneu-moniae and Mycoplasma pneumoniae....
- 10
- 325
- 0
Báo cáo y học: "Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model" ppsx
... fyingthe phosphorylation of protei ns of the cytoskeleton [44].As well as decreasing pro-inflammatory cytotrafficking(cytokines and NO synthesis) [10], acidification and phosphorylation and, in consequence, ... analog scale, and electrodermal activity (EDA). At necropsy (Week 8), macroscopic and histomorphological analyses of synovium, cartilage and subchondral bone of the femoral condyles and tibialplateaus ... purposes, data wer eevaluated separately for lateral and medial osteophytes and also summated for the entire condyles.Histological grading of cartilage and synovial membraneCartilageFull thickness...
- 13
- 361
- 0
Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx
... 2002 Cytochrome c structure and stability (Eur. J. Biochem. 269) 3361 and structure analyses of bacterial cytochromes c, includingHT c-552 and PA c-551.MUTAGENESIS STUDIES FOR STABILITYIn general, ... Yamazaki, K., Kyogoku, Y. &Kobayashi, Y. (1998) Solution structure of thermostable cyto-chrome c-552 from Hydrogenobacter thermophilus determined by1H-NMR spectroscopy. Biochemistry 37, 9641–9649.7. ... the mechanisms of protein maturation, folding, and stabilityYoshihiro Sambongi1, Susumu Uchiyama2,*, Yuji Kobayashi2, Yasuo Igarashi3 and Jun Hasegawa41Graduate School of Biosphere Sciences,...
- 7
- 369
- 0
Báo cáo y học: "Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity" pps
... L. Juliano Structural Bioinformatics Core Facility, University of North Carolina, Chapel Hill, NC 27599, USA3Division of Rheumatology, University of Pennsylvania School of Medicine and Philadelphia ... extremely disordered proteins: implications for the etiology of systemic autoimmunityPhilip L Carl1, Brenda RS Temple2 and Philip L Cohen31Department of Pharmacology, University of North Carolina, ... by Dunker et al. [6,7]. Excellentrecent reviews of protein disorder are provided by Uversky,Gillespie and Fink [8], Fink [9], and Dyson and Wright [10],who call such proteins 'natively...
- 15
- 413
- 0
Báo cáo y học: "Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis" ppsx
... inducinganti-inflammatory cytokines or neutralizing pro-inflammatorycytokines should be critically evaluated before consideringthis form of therapy.Depletion of neutrophils significantly reduced the severity of CAIA ... multicellularinflammatory process, including infiltration of lymphocytes and granulocytes into the articular cartilage, proliferation of synovial fibroblasts and macrophages and neovascularization of the synovial ... by an agalactosylglycoform of anti-CII antibodies [27]. Recent studies alsodemonstrate the impact of differential Fc sialylation on pro- oranti-inflammatory activities of IgG [28].Need for...
- 11
- 457
- 0
Báo cáo y học: "Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects" pot
... of Groups A and B at study days 14 and 28, for Group C subjects at study days28 and 42, and for Group D subjects at study days 70 and 84.Healthy male or female subjects (aged 18–65 years inclusive)with ... serotypes, and approximately 25% of subjectsresponded to at least six different serotypes by day 14 (Figure5a) and by day 28 (Figure 5b).Table 3Geometric means (percentage of the coefficient of ... on study day 14 and on study day 28. This is reflected in serum concentrationsbelow the lower limit of quantification on day 14, and a meanserum concentration of 28.6 μg/ml on study day 28.Subjects...
- 11
- 415
- 0
Báo cáo y học: "Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis" ppsx
... (HMFN0839)* 1-Acylglycerol-3-phosphate O-acyltransferase 9 [GenBank:NM_032717.3]34 MTHFD2 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase[GenBank:NM_006636.3]35 ... Diseases (NIAID), Cooperative Center for Translational Research on Human Immunology and Biodefense, Baylor Institute for Immunology Research and Baylor Research Institute, 3434 Live Oak St, Dallas, ... summary of class prediction analysis.Click here for fileAcknowledgementsThis work was funded by the Baylor Health Care System foundation and the National Institutes of Health (U19 AIO57234-02 and...
- 22
- 395
- 0
Báo cáo y học: " b-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryo" docx
... morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafishembryosYi-Ting Wu1, Che Yi Lin1, Ming-Yuan Tsai2, Yi-Hua Chen3, Yu-Fen Lu3, ... induction of apoptosis of endocardium and erythrocytes. In addition, this study further demonstratesthe importance of endocardium and hemodynamic forces on heart morphogenesis and contractile performance.Keywords: ... causesdeath of the endocardium and erythrocytes in zebrafishembryos resulting in defects i n heart-looping, valve for- mation, and cardiac output. The induction of apoptosis of the endocardium and erythrocytes...
- 13
- 371
- 0
Báo cáo y học: "Computerized tomography myelography with coronal and oblique coronal view for diagnosis of nerve root avulsion in brachial plexus injury" potx
... tomography myelography visual-izing only a part of the rootletsFigure 3Axial view of computerized tomography myelography visual-izing only a part of the rootlets.Publish with BioMed Central and ... visualization of therootlets and orientation of the exact level of the root. Sensitivity and specificity for coronal and oblique coronal views of unrecognition of intradural ventral and dorsal ... conceived the study and performed sur-geries. YH reviewed the images, performed myelography, and helped perform surgeries. SS helped perform surger-ies. All authors read and approved the final...
- 5
- 357
- 0
Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngchuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Định tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀM