Báo cáo y học: "The Heterochromatin Protein 1 family" ppt

... H3 HP1, HP1Mm␣, HP1Mm␤, HP1Mm␥ CD [57,58]Methyl K9 Histone H3 Swi6, HP1, HP1␣, HP1␤, HP1␥ CD [15 ,16 ,18 ]Histone H4 HP1, HP1Mm␣ CSD [ 51, 58]SUV39H1 HP1, HP1␣, HP1␤, HP1␥ CSD [59]Polycomb ... [59]Polycomb HP1Hs␣, HP1Hs␥ CSD [38,60]Dnmt3a HP1Mm␣ ND [42, 61] Dnmt3b HP1␣, HP1␤ ND [ 61] Kap -1/ Tif1␤ HP1␣, HP1␤, HP1␥ CSD [25,62,63]Rb HP1Hs␥ ND [37]MITR HP1Mm␣ Linker [64]BRG1 HP1Mm␣ ... [65]ATRx HP1Mm␣, HP1Mm␤ CSD [66]TAFII 13 0 HP1Hs␣, HP1Hs␥ CSD [67]PIM1 HP1Hs␥ CSD [30]RNA HP1Mm␣, HP1Mm␥ Linker [68]DNA replication and repair proteinsCAF-1p150 HP1␣, HP1␤ CSD...

... receptor/IL-1Rrp.Cytokine 20 01, 13 :1- 7. 10 . Smith DE, Renshaw BR, Ketchem RR, Kubin M, Garka KE, SimsJE: Four new members expand the interleukin -1 superfamily.J Biol Chem 2000, 275 :11 69 -11 75. 11 . Sims ... chondrocytesDavid Magne 1 *, Gaby Palmer 1 *, Jenny L Barton3, Francoise Mézin 1 , Dominique Talabot-Ayer 1 , Sylvette Bas 1 , Trevor Duffy 1 , Marcus Noger3, Pierre-Andre Guerne 1 , Martin ... IL -1 receptor accessory protein (IL-1RAcP), which is necessary for signal transduction.IL-1Ra negatively regulates IL -1 activity by competing with IL- 1 for binding to IL-1RI. Binding of IL-1Ra...

... ratioNC-p1C15S-YFPYFPNC-p1-YFPNC-p1C49S-YFPNC-p1C15-49S-YFPNC-p1R7-YFP0.02Į*)3NC-p1C15S-YFPNC-p1C49S-YFP NC-p1C15-49S-YFP % of specific BRET for wt0%20%40%60%80% 10 0% 12 0% 14 0%wt ... 0.6Total YFP/5 luc rat ioBRET ratioStau1-YFP wtStau1-YFP delta2Stau1-YFP delta3Stau155-YFPStau1'Nt88-YFPStau1'dsRBD3-YFP204060080 10 0 12 00%20%40%60%80% 1 00% 12 0%YFP ... 2.ABĮ<)3503575 10 5 16 0250MockStau155-YFPStau'Nt88-YFPkDaStau155-YFPBRETStau1'Nt88-YFPStau1F135A-YFPCA-p2-NC-p1-5lucStau1'dsRBD3-YFPAC0.000.050 .10 0 .15 0.0 0.2...

... and Vpx in the yeast Schizosaccharomycespombe. Virology 19 97, 230 :10 3 -11 2. 10 8. Zhao Y, Cao J, O'Gorman MR, Yu M, Yogev R: Effect of humanimmunodeficiency virus type 1 protein R (vpr) ... Checkpoint pathways come of age. Cell 19 97, 91: 865-867. 11 5. Smits VA, Medema RH: Checking out the G(2)/M transition. Bio-chim Biophys Acta 20 01, 15 19 :1- 12. 11 6. Mahalingam S, Ayyavoo V, Patel ... immunodeficiency virus type 1 Vpr is a positive regulator of viral transcription and infectiv-ity in primary human macrophages. J Exp Med 19 98, 18 7 :11 03 -11 11. 16 6. Hrimech M, Yao XJ, Bachand...

... receptors. J Neurosci 19 99, 19 :4938-4947.9. Yin Y, Sanes JR, Miner JH: Identification and expression of mouse netrin-4. Mech Dev 2000, 96 :11 5 -11 9. 10 . Yurchenco PD, Wadsworth WG: Assembly and tissue ... Proc Natl Acad Sci USA 2006, 10 3 :11 195 -11 200.5. Nakashiba T, Ikeda T, Nishimura S, Tashiro K, Honjo T, Culotti JG, Itohara S: Netrin-G1: a novel glycosyl phosphatidyli-nositol-linked mammalian ... 32:383- 412 .Published: 29 September 2009 doi :10 .11 86/gb-2009 -10 -9-239 © 2009 BioMed Central Ltd239.7http://genomebiology.com/2009 /10 /9/239 Rajasekharan and Kennedy: Genome Biology 2009, 10 :23927....

... SRp75 1p35.3 Q0 817 0SFRS5 SRp40 14 q24.2 Q13243SFRS6 SRp55 20q13 .11 Q13247SFRS7 9G8 2p22 .1 Q16629SFRS9 SRp30c 12 q24.23 Q13242SFRS 11 SRp54 1p 31. 1 Q05 519 Figure 1 The human SR protein family. The ... Table 1 Human genes encoding SR proteinsGene name SR protein Chromosomal location UniProtSFRS1 SF2/ASF/SRp30a 17 q 21. 3-q22 Q07955SFRS2 SC35/SRp30b 17 q25 .1 Q 011 30SFRS3 SRp20 6p 21. 31 P8 410 3SFRS4 ... for SR proteins. J Cell Biol 19 99, 14 5: 11 45- 11 52.28. Lai MC, Lin RI, Huang SY, Tsai CW, Tarn WY: A human impor-tin-beta family protein, transportin-SR2, interacts with the phosphorylated...

... membrane protein 1 (LMP1). Oncogene 19 98, 16 :17 31- 1742. 11 . Eliopoulos AG, Gallagher NJ, Blake SM, Dawson CW, Young LS: Activationof the p38 mitogen-activated protein kinase pathway by Epstein-Barrvirus-encoded ... and RSK asinventors.Received: 9 February 2 011 Accepted: 18 May 2 011 Published: 18 May 2 011 References 1. Tripp CS, Wolf SF, Unanue ER: Interleukin 12 and tumor necrosis factoralpha are costimulators ... of LMP1 forGupta et al. Retrovirology 2 011 , 8:39http://www.retrovirology.com/content/8 /1/ 39Page 8 of 12 cytokines and b-chemokines is enhanced by singlecycle SIV expressing LMP1 or LMP1-CD40.SIV-LMP1...

... [8 -10 ], human papillomavirus E1 [11 ], and her-pesvirus K8 [12 ] as well as cellular factors c-MYC [13 ],ALL1 (MLL) [14 ], GADD34 [15 ], and p53 [16 ]. Duringthe early phase of the HIV -1 life cycle, ... immunodeficiency virus type 1 (HIV -1) into the host genome is catalyzed bythe viral integrase (IN) and preferentially occurs within transcriptionally active genes. During theearly phase of HIV -1 infection, ... activityHIV -1- LTR-LucTat:IN I- 1 :----++ 10 00++ 1. 2 1. 00. 80. 60. 40. 20A570integ ra te d HIV -1- LTR-ββββ-galTat:IN I1 :---++-++a.b.40 030 020 0 10 00HIV -1- LTR-LucRelative...

... hHs_SHHDr_shhaDr_shhb 10 084Mm_DhhHs_DHH86 10 0Mm_IhhHs_IHH 61 100Dr_ihhaDr_ihhb5793Tr_fhh 10 0Dh_HhDm_HhAg_Hh 10 0At_Hh97Cap_Hh42Dr_dhhXC_HhTs_hhNv_HH2Nv_Hint3Acm_DY57 918 5Cap_ 213 608Lg_236 513 9757Nv_Hint1Nv_Hint284 1 Nv_HH1aKm_HogaAt_HogTs_Xhog3aAc_Hog 10 0aCp_HogaCm_HogHm_CO905822cBn_Hog 10 040XC_Shog1XC_Shog1bXC_XHog4 10 0XC_Thog50XC_Xhog5 91 Ts_Xhog245Ts_Xhog152Cb_qua -1 Cr_qua -1 Ce_qua -1 95Bm_qua -1 100XC_Xhog1Ts_qua -1 10089XC_Xhog2XC_Xhog3 51 100Ce_grd -1 Cb_grd -1 Ce_grd-2 10 0Ce_grd -11 Ce_hog -1 Cb_hog -1 100 10 0Ce_wrt -1 Cb_wrt -1 Ce_wrt-6Cb_wrt-6Bm_wrt-6 10 0Ce_wrt-4Cb_wrt-4Ce_wrt-7Ce_wrt-898 10 0 10 0 10 0 10 040 10 073679248 10 0SpongeHhWRTGRDQUAVint0.05ChromadoreaEnopleaProtistCnidariaLophotrochozoaDeuterostomesArthropodaLophohogwhich ... Parasitol 19 50, 3366:: 10 7 -11 2.http://genomebiology.com/2008/9 /11 /2 41 GenomeBBiioollooggyy2008, Volume 9, Issue 11 , Article 2 41 Bürglin 2 41. 9Genome BBiioollooggyy 2008, 99::2 41 http://genomebiology.com/2008/9 /11 /2 41 GenomeBBiioollooggyy2008, ... Dev2004, 11 88::6 41- 659.http://genomebiology.com/2008/9 /11 /2 41 GenomeBBiioollooggyy2008, Volume 9, Issue 11 , Article 2 41 Bürglin 2 41. 8Genome BBiioollooggyy 2008, 99::2 41 Very recent findings...

... November 2009 doi :10 .11 86/gb-2009 -10 -10 -11 2 © 2009 BioMed Central Ltd 11 2.3http://genomebiology.com/2009 /10 /10 /11 2 Petsko: Genome Biology 2009, 10 :11 2Mink: Exactly the same way they found the genes ... chops. 11 2.4http://genomebiology.com/2009 /10 /10 /11 2 Petsko: Genome Biology 2009, 10 :11 2Clifford: That’s because we’re a superior species.Mink: Obviously. After all, who lies around all day and ... http://genomebiology.com/2009 /10 /10 /11 2 Petsko: Genome Biology 2009, 10 :11 2In the world which we know, among the different and primitive geniuses...