... Article R113
Method
A novel approach to identifying regulatory motifs in distantly
related genomes
Ruth Van Hellemont
*
, Pieter Monsieurs
*
, Gert Thijs
*
, Bart De Moor
*
,
Yves Van de Peer
†
... successful in the identification of regulatory motifs, phylogenetic footprinting
methods still show some shortcomings. To assess these difficulties, most apparent when ap...
... other factors may
explain the failure of MMP inhibitors in clinical trials. For
instance, some members of the MMP family were recently
shown to exert an anti-inflammatory activity in some physiolog-
ical ... stimulated by inflammatory
cytokines [21,22]. To assess whether inflammation does cor-
relate with the proteolytic activity in arthritic joints, we first
compared the NPA with t...
... later
complaining that the pain in his left calf area persisted
and could be further aggravated by tiptoeing and weight
bearing maneuvers. Again, US examination in the prone
position did n ot reveal any ... sonographic findings. However, he still complained of persistent pain in his left calf area. A
different ultrasound examination approach was then performed with the patient lying...
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Considering the mass flux of fluid into an REV, and by further d efining R* Δx y z
to be the volumetric inflow rate (with R* > 0 referring to ... soaking in excess water. However , swelli ng does
not hint to any permeability property, but simply means that corneocytes contain pro-
teins that can bind water mol...
... used to obtain DNA-microarray data of improved
quality.
A novel scheme to assess factors involved in the reproducibility of DNA-microarray
data
Running title: a novel scheme to assess ... due to hybridization
and sampling.
Some factors are confounded
Due to the fact that in our DNA-microarray laboratory validation experiments are only
performed when necessary...
...
Symptoms in HCV infection do not appear to be
linked to disease activity; neither do appear to be
correlated with serum aminotransferase levels or liver
histological findings [15,16]. In ... A phase II study indicated
a lower rate of anemia induced by viramidine than
ribavirin. However, its efficacy remains to be determined
by ongoing clinical trials. Several types of HCV-s...
... hepatic inflammation carry a significantly higher risk of
disease progression. Histological staging of HBV disease is clinically very valuable in assessing degree of fibrosis and predicting
disease ... liver biopsy may not be necessary. As it will be discussed below, histological assessment is very valuable in determining HBV
treatment in patients with persistently normal transaminas...
... basic indexing
methods by presenting a novel approach using a con-
cept vector space model for extracting and weighting
indexes. Our experiment for semantic indexing sup-
ports the validity of ... index term extraction
based on the concept vector space, which will be ex-
plained in the next section.
3.2 Lexical Chains and Concept Vector Space
Model
Lexical chains are employed to link...
... behavior can only yield partial insight
into circadian entrainment. It is presently impossible to
directly measure SCN activity in vivo, and thus it is impos-
sible to measure entrainment in the purest ... they
returned the device for data analyses. In addition to wear-
ing the Daysimeter, participating nurses provided urine
samples, obtained every four hours, for subsequent mela-...
... mixture of baits.
For example, intravenously administered phage display
library has been successfully used for in vivo bio-panning
in certain animal model systems to identify tissue-specific
peptide ... synthetic biotinylated TMG
peptide (Fig. 1C, TMG). Conversely, phages displaying the
TMG peptide bind to a synthetic biotinylated DSP peptide
(Fig. 1C, DSP). In the absence of biotin...