... was analyzed for plasma renin activity (PRA) and angiotensin II concentration (Ang II). Using near-infrared spectroscopy, wemeasured the rate of increase in the oxygen saturation of thenar microvascular ... fulfilled enrollment criteria,including 1) severe sepsis, defined as signs of systemicinflammation in the setting of probable or confirmedinfection, as originally described in a consensus state-ment ... vasoconstrictors include Dopamine > 15 mcg/kg/min or Norepinephrine > 0.1 mcg/kg/min. Since th evalidation of SOFA scores, arginine vasopressin infusionshave been shown to decrease the need for additionalvasopressors...