Báo cáo y học: "All motifs are not created equal: structural properties of transcription factor - dna interactions and the inference of sequence specificity" doc
... to
DNA had been determined by x-ray crystallography, and computed the number of
contacts between each base in the bound DNA and the protein. For each factor they
assembled collections of sequences ... factor given its amino acid sequence (reviewed in [6]). In a second
All Motifs are NOT Created Equal:
Structural Properties of Transcription Facto...
... quantify the similarity of
their molecular functions. By studying the distributions of
semantic distances for each class of duplicate, their propen-
sity to share functional annotations was compared ... over-repre-
sentation of these classes among SSD genes). Thus, the phe-
notypic asymmetry between the two classes of duplicate is not
because they encode proteins that have...
... http://ccforum.com/content/13/6/430
Page 1 of 2
(page number not for citation purposes)
Following the publication of our article [1] we noticed that
three of the figures were incorrectly numbered and positioned
with respect to the ... Bakker J and Gommers
D: End-expiratory lung volume during mechanical ventilation:
a comparison with reference values and the effect of p...
... binding site. These
were: Asp-Ala-His-NH
2
(DAHam) and Asp-Ala-His-Lys-
NH
2
(DAHKam), which represent the native HSA
sequence and Val-Ile-H is-Asn ( VIHN), t he N-terminal
peptide o f another blood ... Szewczuk
1
and Wojciech Bal
1,2
1
Faculty of Chemistry, University of Wroclaw, Poland;
2
Institute of Biochemistry and Biophysics, Polish Academy of Sciences,
Warsaw, Polan...
... C-terminal regions did not acti-
vate CA promoter and strongly repressed the c-fos promoter,
independently of the origin of the N-terminal region.
The lack of activity of the A. franciscana C-terminal
region ... coded for the N-terminal region, including the
MADS box, from one species and the C-terminal region
from another. The consequences of the co-expres...
... explained how
knowledge of the biosynthetic pathways of glycans is critical
for interpreting MS data and used the altered glycosylation
status of haptoglobin in the sera of patients with prostate
cancer ... help
improve analysis of protein structure and function. Using
X-ray crystallography to understand protein function can
lead to the discovery of new therapeutic age...
... the phosphorylation of ERK
1/2
and the activation of
AP-1 and NF-IL-6 pathways, but not of NF-κB. These effects
were reproduced by the MEK1 inhibitor PD-98059, suggest-
ing that inhibition of ... mitogen-activated protein extracellularly regulated kinase kinase 1; MMP: matrix metallopro-
tease; MTT: 3-( 4,5-dimethylthiazol-2-yl )-2 ,5-diphenyl-2H-tetrazolium bromide; N...
... using age stra ta
(namely, 1 5-1 9, 2 0-2 4, 2 5-2 9, 3 0-3 4, 3 5-3 9, 4 0-4 4, 4 5-4 9,
5 0-5 4, 5 5-5 9, 6 0-6 4, 6 5-6 9, 7 0-7 4, 7 5-7 9, 8 0-8 4, 8 5-8 9,
and 90+) and also by gender and ethnicity strata for
speci fic ... individuals
with SMI are higher than that of the general community
[ 6-8 ]. A previous longitudinal register-based study w...
... synthesize the published RCTs, evaluate safety, assess
short-term efficacy and long-term sequel of LVRS by systemic review
and meta-analysis.
Meta-analysis suggested that postoperative mortality of ... compare the efficacy and safety of LVRS vs conservative
medical therapy. One RCT was obtained regarding comparison of
median sternotomy (MS) and video-assisted thoracosc...