Báo cáo y học: "A non-random walk through the genome" pdf

Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot

... C-terminally to the CBM that play speciﬁc roles in activation of the receptor by these two cytokines. The ligand independent activation of the D5-GCSFR chimera occurs in both the absence and the presence ... antibody 10B2 (LIFR) followed by phycoerythrin-conjugated secondary antibody (black histograms). As a negative control, mock-transfected cells were treated in the same way (...

Ngày tải lên : 18/03/2014, 01:20

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Báo cáo Y học: Activation of transcription through the ligand-binding pocket of the orphan nuclear receptor ultraspiracle docx

... binding of methyl epoxyfar- nesoate, then the change in the local environment of the two added tryptophan residues on a-helix 12 may change their ﬂuorescence in a way that yields a markedly different ... methyl epoxyfarnesoic acid (yellow carbon backbone and blue terminal carboxylate oxygens) lain manually in the dUSP ligand-binding pocket with the carboxy and distal (epoxy) ends, r...

Ngày tải lên : 23/03/2014, 21:20

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Báo cáo y học: "A case study evaluating the use of clozapine in depression with psychotic feature" docx

... limited. The only evidence specific for the question is limited to low-level evidence with only case study/series evidence. The higher quality evidence is limited by being non-specific, especially ... ideation. There was no history of alcohol/substance misuse or any medical prob- lems. She had been receiving ECT treatment twice weekly in the community for the 4 months preceding t...

Ngày tải lên : 08/08/2014, 21:20

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Báo cáo y học: "Transfers to psychiatry through the consultation-liaison psychiatry service: 11 years of experience" pdf

... than on the treatment of their somatic illness, their transfer to psychiatry often appears the only way to deal with them. In addition, the negative feelings of the doctors, the staff, and the rest ... rehabilitation psychiatric services but also by pressure from physicians and, of course, by the understanding on the psychiatrist's side of the stress the physicians an...

Ngày tải lên : 08/08/2014, 23:20

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Báo cáo y học: "A short review on the aetiology and pathophysiology of alcoholism" ppt

... Hesselbrock V, Meyer RE, Dolin- sky ZS, Rounsaville B: Types of alcoholics. I: evidence for an empirically derived typology based on indicators of vulnerability and severity. Arch Gen Psychiatry 1992, ... individuals with a family vulnerability to alcoholism. Am J Psychiatry 2004, 161(10):1776-1782. 27. Yudofsky SC, Hales RH: The American Psychiatric Publishing textbook of neuropsychiatry...

Ngày tải lên : 08/08/2014, 23:21

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Báo cáo y học: "γ A novel mechanism for the regulation of IFN-γ inducible protein-10 expression in rheumatoid arthritis" ppsx

... primary antibody, and biotinylated polyclonal goat anti-IP-10 (0.1 µg/ml) served as the secondary antibody. The sensi- tivity limit for the IP-10 enzyme-linked immunosorbent assay was approximately ... regulated not only by inflammatory cytokines but also by the physical interaction of activated leukocytes with fibroblast-like synoviocytes, and that IP-10 may contribute to the recru...

Ngày tải lên : 09/08/2014, 01:21

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Báo cáo y học: "A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer." pps

... lacking glycosylation [26]. In the first part of the present study similar end-point levels of transgenic and recombinant IL-1Ra were necessary to inhibit fully the response of synoviocytes to ... methionine, the native molecule may have greater bio- logic potency than the recombinant one. The present study was designed to compare quantitatively the relative effectiveness of the...

Ngày tải lên : 09/08/2014, 01:23

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Báo cáo y học: " A promoter haplotype of the interleukin-18 gene is associated with juvenile idiopathic arthritis in the Japanese population" pps

... polyarthritis and systemic subgroups, the frequency of haplotype S01 did not differ statistically from that of healthy controls. The frequency of haplotype S01 was also significantly higher in the patients ... participated in the design and coordination of the study, and recruited a subset of the patients. ST conceived the study together with Y Kawano and participated in the...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: "A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis" doc

... when interpreting the data. The primary limitation is the heterogeneity among studies in terms of the data sources, populations examined, and study designs. The diversity of study methodologies ... between rheumatology and oncology departments. Uncertainty regarding the size of the RA population evaluated may account for their very high reported relative risk of 7.4 for Hodgki...

Ngày tải lên : 09/08/2014, 10:23

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Báo cáo y học: "A meta-analysis of the efficacy of fibromyalgia treatment according to level of care" pptx

... although both of these are biased by the heterogeneity of the studies. Other variables that also improve out- come, which are not biased by the heterogeneity of the studies, are younger patient ... summarised the results of the most fre- quently used in the studies revised: global function, pain and FIQ. The quality of the studies was rather low with only one- third of the...

Ngày tải lên : 09/08/2014, 10:23

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